WormBase Tree Display for Variation: WBVar00252110

WBVar00252110 Name: Public_name: tm3425
    Other_name: C56C10.12.1:c.474_1139-23del
    HGVSg: CHROMOSOME_II:g.6608000_6608738del
  Sequence_details: SMap: S_parent: Sequence: F54H5
    Flanking_sequences: ggcaattactgaaatacattcatattcaac ggatgttgaagcgcatcagtataggatgga
    Mapping_target: F54H5
    Source_location: 7 CHROMOSOME_II 6607999 6608739 Inferred_automatically: National_Bioresource_Project
    Type_of_mutation: Deletion
    PCR_product: tm3425_external
      tm3425_internal
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00055854
    Laboratory: FX
    Author: Mitani S
    DB_info: Database: National_Bioresource_Project seq 3425
    NBP_allele
    Status: Live
  Affects: Gene: WBGene00016968
    Transcript: C56C10.12.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: C56C10.12.1:c.474_1139-23del
        cDNA_position: 483-?
        CDS_position: 474-?
        Protein_position: 158-?
        Intron_number: 5-6/24
        Exon_number: 5-6/25
    Interactor: WBInteraction000517937
      WBInteraction000521392
      WBInteraction000521394
      WBInteraction000521400
      WBInteraction000521401
      WBInteraction000521408
      WBInteraction000525233
      WBInteraction000525258
  Isolation: Mutagen: TMP/UV
  Genetics: Map: II
  Description: Phenotype (11)
    Phenotype_not_observed: WBPhenotype:0000062 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Classified as homozygous viable by the National Bioresource Project of Japan. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
            Laboratory_evidence: FX
      WBPhenotype:0000590 Paper_evidence: WBPaper00044390
        Curator_confirmed: WBPerson2987
        Remark: epg-5(tm3425) mutants did not exhibit changes in the number of germ cell corpses that were observed in animals 48 hours post-L4 larval stage (Figure S1E) Paper_evidence: WBPaper00044390
            Curator_confirmed: WBPerson2987
      WBPhenotype:0000699 Paper_evidence: WBPaper00042320
        Curator_confirmed: WBPerson712
        Remark: Autophagy mutants did not show defects in vulval development. Paper_evidence: WBPaper00042320
            Curator_confirmed: WBPerson712
      WBPhenotype:0000701 Paper_evidence: WBPaper00042320
        Curator_confirmed: WBPerson712
        Remark: Mutants exhibited normal seam cell development Paper_evidence: WBPaper00042320
            Curator_confirmed: WBPerson712
      WBPhenotype:0001225 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Comments to the National Bioresource Project of Japan: Dr. H. Sawa: not Psa Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
            Laboratory_evidence: FX
  Reference: WBPaper00036384
    WBPaper00042320
    WBPaper00044390
    WBPaper00065712
  Remark: 33713/33714-34452/34453 (739 bp deletion)
    This knockout was generated by the National Bioresource Project, Tokyo, Japan, which is part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence: WBPaper00041807
    Old Mapping_target C56C10 updated based on the VEP analysis pipeline to F54H5.
  Method: NBP_knockout_allele