WormBase Tree Display for Variation: WBVar00252803

WBVar00252803 Name: Public_name: tm4293
    Other_name: ZK662.4.2:c.1652_2246delinsTT
      CE15381:p.Lys551IlefsTer5
      ZK662.4.1:c.1652_2246delinsTT
    HGVSg: CHROMOSOME_X:g.15728791_15729385delinsTT
  Sequence_details: SMap: S_parent: Sequence: ZK678
    Flanking_sequences: ttgctggaaactatcaaacatttcgtggaa tccttcaactgatccggtgccaaaccgaac
    Mapping_target: ZK678
    Source_location: 7 CHROMOSOME_X 15728790 15729386 Inferred_automatically: National_Bioresource_Project
    Type_of_mutation: Insertion: TT
      Deletion
    PCR_product: tm4293_external
      tm4293_internal
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Laboratory: FX
    Author: Mitani S
    DB_info: Database: National_Bioresource_Project seq 4293
    NBP_allele
    Status: Live
  Affects: Gene: WBGene00023497
    Transcript: ZK662.4.1 VEP_consequence: frameshift_variant
        VEP_impact: HIGH
        HGVSc: ZK662.4.1:c.1652_2246delinsTT
        HGVSp: CE15381:p.Lys551IlefsTer5
        cDNA_position: 1658-2252
        CDS_position: 1652-2246
        Protein_position: 551-749
        Exon_number: 6/10
        Codon_change: aAAGGAGCATCGGTGGATGTCATTTCTCAATCAATGATTGAGACTTTAAATAACACTGCAAGTCGTCTTCAGAAGCAGGTTCACCTTGGTCTTTATGCACACGGAGTTGACAACATCTCTTCTGATCGAGATGTGCAATCCATTGTCGGCCATCACTACCCTCCGATGCCAACAGTTGCAAACTATGACATTCCACACGTGCCGAAAGAAGAAGAGAAGCCTCCAGTGGCTAACCTGCAAAGTACATCTAGCCCAGCGACGTCCTCTCCAACAATCATCCGCCCTCGTGCAGCACCTCCACCGAGAACACTGGCTCAAGGAAGACCAATCCCGTTGAATGGGAAAGAACTCAAGGCTGTTCCAATCAGGCAGATTCCGCTGCAAGTGAGGCCGTTGCCACCGAGACCAGCCAATGTGCCAATTGTGCCAAGGCCAACTGTTCCACAACAGTTTATCAAAGCACCAGCTCCGAAACCTATCACACTTCAAGCTGTTGTTTGCAGTATTCCAGAAAAGGAAATCAAGAAAGAAACTGAAGACGTAGCGCTGCTGGAGAAAATAAAGGATGAACCACTGGATGAAGACGATTTTAATCAt/aTTt
        Amino_acid_change: KGASVDVISQSMIETLNNTASRLQKQVHLGLYAHGVDNISSDRDVQSIVGHHYPPMPTVANYDIPHVPKEEEKPPVANLQSTSSPATSSPTIIRPRAAPPPRTLAQGRPIPLNGKELKAVPIRQIPLQVRPLPPRPANVPIVPRPTVPQQFIKAPAPKPITLQAVVCSIPEKEIKKETEDVALLEKIKDEPLDEDDFNH/IX
      ZK662.4.2 VEP_consequence: frameshift_variant
        VEP_impact: HIGH
        HGVSc: ZK662.4.2:c.1652_2246delinsTT
        HGVSp: CE15381:p.Lys551IlefsTer5
        cDNA_position: 1664-2258
        CDS_position: 1652-2246
        Protein_position: 551-749
        Exon_number: 6/11
        Codon_change: aAAGGAGCATCGGTGGATGTCATTTCTCAATCAATGATTGAGACTTTAAATAACACTGCAAGTCGTCTTCAGAAGCAGGTTCACCTTGGTCTTTATGCACACGGAGTTGACAACATCTCTTCTGATCGAGATGTGCAATCCATTGTCGGCCATCACTACCCTCCGATGCCAACAGTTGCAAACTATGACATTCCACACGTGCCGAAAGAAGAAGAGAAGCCTCCAGTGGCTAACCTGCAAAGTACATCTAGCCCAGCGACGTCCTCTCCAACAATCATCCGCCCTCGTGCAGCACCTCCACCGAGAACACTGGCTCAAGGAAGACCAATCCCGTTGAATGGGAAAGAACTCAAGGCTGTTCCAATCAGGCAGATTCCGCTGCAAGTGAGGCCGTTGCCACCGAGACCAGCCAATGTGCCAATTGTGCCAAGGCCAACTGTTCCACAACAGTTTATCAAAGCACCAGCTCCGAAACCTATCACACTTCAAGCTGTTGTTTGCAGTATTCCAGAAAAGGAAATCAAGAAAGAAACTGAAGACGTAGCGCTGCTGGAGAAAATAAAGGATGAACCACTGGATGAAGACGATTTTAATCAt/aTTt
        Amino_acid_change: KGASVDVISQSMIETLNNTASRLQKQVHLGLYAHGVDNISSDRDVQSIVGHHYPPMPTVANYDIPHVPKEEEKPPVANLQSTSSPATSSPTIIRPRAAPPPRTLAQGRPIPLNGKELKAVPIRQIPLQVRPLPPRPANVPIVPRPTVPQQFIKAPAPKPITLQAVVCSIPEKEIKKETEDVALLEKIKDEPLDEDDFNH/IX
  Isolation: Mutagen: TMP/UV
  Genetics: Map: X
  Description: Phenotype_not_observed: WBPhenotype:0000062 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson2021
        Remark: Classified as homozygous viable by the National Bioresource Project of Japan. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson2021
  Remark: [ZK678] 1299/1300-TT-[ZK678] 1894/1895 (595 bp deletion + 2 bp insertion)
    This knockout was generated by the National Bioresource Project, Tokyo, Japan, which is part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence: WBPaper00041807
  Method: NBP_knockout_allele