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WormBase Tree Display for Variation: WBVar02125780

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Name Class

WBVar02125780EvidencePaper_evidenceWBPaper00041219
NamePublic_namevt33
Sequence_detailsSeqStatusPending_curation
Variation_typeAllele
OriginSpeciesCaenorhabditis elegans
LaboratoryBY
StatusLive
DescriptionPhenotypeWBPhenotype:0000179Paper_evidenceWBPaper00053894
Curator_confirmedWBPerson557
RemarkDopamine neuron degeneration observed in swip-10(vt33).Paper_evidenceWBPaper00053894
Curator_confirmedWBPerson557
Phenotype_assayGenotypevtIs7 [Pdat-1::gfp]Paper_evidenceWBPaper00053894
Curator_confirmedWBPerson557
WBPhenotype:0000273Paper_evidenceWBPaper00041219
Curator_confirmedWBPerson712
RemarkMutants recovered in the screen demonstrated significantly reduced maximal thrashing frequencies in water.Paper_evidenceWBPaper00041219
Curator_confirmedWBPerson712
WBPhenotype:0000905Paper_evidenceWBPaper00053894
Curator_confirmedWBPerson557
RemarkShrunken or missing CEP cell soma.Paper_evidenceWBPaper00053894
Curator_confirmedWBPerson557
Phenotype_assayGenotypevtIs7 [Pdat-1::gfp]Paper_evidenceWBPaper00053894
Curator_confirmedWBPerson557
WBPhenotype:0001236Paper_evidenceWBPaper00053894
Curator_confirmedWBPerson557
RemarkAnimals have a significant increase in fluorescence of a basal whole body oxidative stress reporter, dvIs19[pgst-4:GFP].Paper_evidenceWBPaper00053894
Curator_confirmedWBPerson557
Phenotype_assayGenotypedvIs19[pgst-4:GFP]Paper_evidenceWBPaper00053894
Curator_confirmedWBPerson557
WBPhenotype:0001398Paper_evidenceWBPaper00053894
Curator_confirmedWBPerson557
RemarkNeurite truncations and breaks in GFP along CEP dendrites.Paper_evidenceWBPaper00053894
Curator_confirmedWBPerson557
Phenotype_assayGenotypevtIs7 [Pdat-1::gfp]Paper_evidenceWBPaper00053894
Curator_confirmedWBPerson557
WBPhenotype:0002114Paper_evidenceWBPaper00041219
Curator_confirmedWBPerson712
RemarkThis mutant demonstrates a stable Swip phenotype and can be rescued by reserpine pretreatment. Phenotype not lost after 3X outcrossing.Paper_evidenceWBPaper00041219
Curator_confirmedWBPerson712
Affected_byMoleculeWBMol:00002955Paper_evidenceWBPaper00041219
Curator_confirmedWBPerson712
ReferenceWBPaper00041219
WBPaper00053894
MethodAllele