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WormBase Tree Display for Variation: WBVar02157822

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Name Class

WBVar02157822Possibly_affectsWBGene00020142
DescriptionPhenotypeWBPhenotype:0000306Paper_evidenceWBPaper00064230
Curator_confirmedWBPerson712
Remarkwe pre-treated animals for 10-minutes with paraquat and metformin solution and immobilized them with a solution of sodium azide, while in the presence of paraquat and metformin. Following treatment, wild-type animals displayed a significant increase in normalized FRET ratios over time, compared to untreated controls (Fig.1E), while aak-2(T243A) and aak-2(S244G) showed no change in normalized ratios between the treatment and control groups (Fig.1F).Paper_evidenceWBPaper00064230
Curator_confirmedWBPerson712
Phenotype_assayTreatmentpre-treatment with paraquat and metformin solutionPaper_evidenceWBPaper00064230
Curator_confirmedWBPerson712
GenotypestjEx216[nhx-2p::ceAMPKAR-EV; myo-2p::mCherry]Paper_evidenceWBPaper00064230
Curator_confirmedWBPerson712
WBPhenotype:0000523Paper_evidenceWBPaper00064230
Curator_confirmedWBPerson712
Remarkwe pre-treated animals for 10-minutes with paraquat and metformin solution and immobilized them with a solution of sodium azide, while in the presence of paraquat and metformin. Following treatment, wild-type animals displayed a significant increase in normalized FRET ratios over time, compared to untreated controls (Fig.1E), while aak-2(T243A) and aak-2(S244G) showed no change in normalized ratios between the treatment and control groups (Fig.1F).Paper_evidenceWBPaper00064230
Curator_confirmedWBPerson712
Phenotype_assayTreatmentpre-treatment with paraquat and metformin solutionPaper_evidenceWBPaper00064230
Curator_confirmedWBPerson712
GenotypestjEx216[nhx-2p::ceAMPKAR-EV; myo-2p::mCherry]Paper_evidenceWBPaper00064230
Curator_confirmedWBPerson712
ReferenceWBPaper00064230