WormBase Tree Display for Gene: WBGene00000088

WBGene00000088 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: F32A7
  Identity: Version: 1
    Name: CGC_name: aex-5 Person_evidence: WBPerson655
      Sequence_name: F32A7.6
      Molecular_name: F32A7.6
        F32A7.6.1
        CE28554
      Other_name: kpc-3
        kpc-5
        CELE_F32A7.6 Accession_evidence: NDB BX284601
      Public_name: aex-5
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:20 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: aex
    Allele: WBVar00242461 Inferred_automatically: From strain object: JT23
      WBVar00242473
      WBVar00242474
      WBVar00242472
      WBVar00353404
      WBVar00353405
      WBVar00301658
      WBVar00301659
      WBVar00263891
      WBVar00309679
      WBVar00301660
      WBVar00309680
      WBVar00298090
      WBVar00298091
      WBVar00309681
      WBVar01435099
      WBVar01499908
      WBVar00314413
      WBVar00314414
      WBVar00314415
      WBVar01499739
      WBVar00304000
      WBVar00304001
      WBVar02146396
      WBVar02146397
      WBVar00307581
      WBVar00307582
      WBVar02017112
      WBVar00307583
      WBVar02129132
      WBVar02017114
      WBVar02129133
      WBVar01958870
      WBVar02129134
      WBVar01231898
      WBVar01231899
      WBVar01231900
      WBVar00162605
      WBVar00162606
      WBVar00162607
      WBVar00240210
      WBVar00305051
      WBVar00162608
      WBVar01494437
      WBVar00305052
      WBVar00305053
      WBVar00162609
      WBVar00162610
      WBVar00162611
      WBVar00162612
      WBVar00162613
      WBVar00162614
      WBVar00162615
      WBVar01290586
      WBVar01290587
      WBVar00308688
      WBVar01290588
      WBVar00308689
      WBVar00259736
      WBVar01290590
      WBVar00308690
      WBVar01290591
      WBVar01290592
      WBVar01290594
      WBVar01894843
      WBVar01290597
      WBVar01236485
      WBVar01290598
      WBVar01290599
      WBVar01290600
      WBVar01290603
      WBVar01290609
      WBVar01290611
      WBVar00694385
      WBVar02068095
      WBVar01499066
      WBVar00694386
      WBVar00694387
      WBVar00694388
      WBVar00694389
      WBVar00694390
      WBVar00694391
      WBVar00694392
      WBVar01502753
      WBVar00694393
      WBVar00694394
      WBVar00694395
      WBVar01499627
      WBVar01603038
      WBVar01499628
      WBVar00694396
      WBVar00694397
      WBVar00694398
      WBVar01499999
      WBVar00694399
      WBVar00694400
      WBVar00694401
      WBVar00694402
      WBVar00694403
      WBVar00694404
      WBVar00694405
      WBVar00694406
      WBVar00694407
      WBVar01499823
      WBVar00694408
      WBVar00694409
      WBVar00694410
      WBVar00694411
      WBVar00694412
      WBVar00694413
      WBVar00694414
      WBVar00694415
      WBVar00694416
      WBVar00299473
      WBVar00299474
      WBVar00694417
      WBVar00299475
      WBVar00694418
      WBVar00694419
      WBVar00299476
      WBVar00694420
      WBVar00694421
      WBVar00694422
      WBVar00694423
      WBVar00694424
      WBVar00694425
      WBVar00694426
      WBVar01499298
      WBVar00296975
      WBVar00296976
      WBVar00276464
      WBVar00296977
      WBVar00296978
      WBVar00303040
      WBVar00303041
      WBVar00303042
      WBVar00310866
      WBVar00316139
      WBVar01498939
      WBVar00310867
      WBVar00316140
      WBVar00316141
      WBVar00310868
      WBVar00310869
      WBVar00316142
      WBVar00310870
      WBVar00316143
      WBVar01412338
      WBVar00310871
      WBVar02076734
      WBVar00300765
      WBVar00300766
      WBVar00300767
      WBVar01948654
      WBVar00264053
      WBVar00306234
      WBVar00306235
      WBVar00353395
      WBVar00306236
      WBVar00353396
      WBVar00306237
      WBVar00353397
      WBVar00353398
      WBVar00353399
      WBVar00265901
      WBVar00353400
      WBVar00353401
      WBVar00353402
      WBVar01911944
      WBVar00353403
    Legacy_information: [Jim Thomas] Defecation defective, moderate to severe constipation, expulsion muscle contraction (Exp) missing in about 9 of 10 defecation cycles, anterior body contraction (aBoc) usually missing as well, adult males unaffected and mate well.
      See also sa23, sa41, sa42, sa43
      [C.elegansII] sa23 : defecation defective, moderate to severe constipation, expulsion muscle contraction (Exp) missing in about 9 of 10 defecation cycles, anterior body contraction (aBoc) usually missing as well, adult males unaffected and mate well. OA3: sa41, sa42, sa43 (all similar) [Thomas 1990; JT]
    Strain: WBStrain00022773
    RNASeq_FPKM (74)
    GO_annotation (29)
    Ortholog (47)
    Paralog: WBGene00001172 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00000254 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00002232 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00017686 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: an ortholog of calcium-dependent serine endoproteinases, the kex2/subtilisin-like proprotein convertase that affects defecation cycle and anterior body contractions; and is expressed in all muscle cells except pharyngeal muscles. Paper_evidence: WBPaper00004142
          Curator_confirmed: WBPerson480
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Enables serine-type endopeptidase activity. Involved in several processes, including neuropeptide processing; positive regulation of synaptic assembly at neuromuscular junction; and positive regulation of transport. Located in extracellular space. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F32A7.6
    Corresponding_CDS_history: F32A7.6:wp56
    Corresponding_transcript: F32A7.6.1
    Other_sequence: Oden_isotig22904
      Acan_isotig14016
      Tcir_isotig22927
      CJC17003_1
    Associated_feature: WBsf649782
      WBsf220659
      WBsf220660
  Experimental_info: RNAi_result (36)
    Expr_pattern: Expr1010377
      Expr1149978
      Expr2009250
      Expr2027487
    Drives_construct: WBCnstr00037741
    Construct_product: WBCnstr00005315
      WBCnstr00007723
      WBCnstr00037741
    Microarray_results (19)
    Expression_cluster (145)
    Interaction: WBInteraction000001570
      WBInteraction000028975
      WBInteraction000165455
      WBInteraction000519683
      WBInteraction000524187
      WBInteraction000557476
      WBInteraction000557477
      WBInteraction000557478
    WBProcess: WBbiopr:00000010
  Map_info (4)
  Reference (34)
  Remark: Sequence connection from [Thacker C]
    old_name kpc-5 becomes new_name aex-5 from [Thacker C].
  Method: Gene