WormBase Tree Display for Gene: WBGene00005153

WBGene00005153 SMap: S_parent: Sequence: CHROMOSOME_IV
  Identity: Version: 2
    Name: CGC_name: srf-3 Person_evidence: WBPerson494
      Sequence_name: M02B1.1
      Molecular_name: M02B1.1a
        M02B1.1a.1
        CE43555
        M02B1.1b
        CE37656
        M02B1.1c
        CE45668
        M02B1.1b.1
        M02B1.1c.1
      Other_name: CELE_M02B1.1 Accession_evidence: NDB BX284604
      Public_name: srf-3
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History (2)
    Status: Live
  Gene_info (12)
  Disease_info: Experimental_model: DOID:104 Homo sapiens Paper_evidence: WBPaper00006215
          Curator_confirmed: WBPerson324
          Date_last_updated: 07 Nov 2023 00:00:00
    Potential_model: DOID:0070265 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:11022)
    Disease_relevance: C. elegans is used as a model system to study bacterial adherence via biofilm formation and to identify genes in the infectious agent as well as the host that are required for infection; elegans srf genes are required for cuticle surface properties like binding to antigens, and for the adherence of bacterial pathogens like Yersinia pseduotuberculosis and Yersinia pestis via biofilms. Homo sapiens Paper_evidence: WBPaper00001706
            WBPaper00026735
            WBPaper00029153
          Curator_confirmed: WBPerson324
          Date_last_updated: 06 Mar 2013 00:00:00
  Models_disease_in_annotation: WBDOannot00000015
  Molecular_info: Corresponding_CDS: M02B1.1a
      M02B1.1b
      M02B1.1c
    Corresponding_CDS_history: M02B1.1:wp109
      M02B1.1:wp133
      M02B1.1:wp201
    Corresponding_transcript: M02B1.1a.1
      M02B1.1b.1
      M02B1.1c.1
    Other_sequence: CRC11400_1
      FC815126.1
      PPC11536_1
      JI467852.1
      CR05429
      SRC00576_1
      JO472062.1
      SR01573
      Name_isotig07744
      JI171965.1
    Associated_feature: WBsf646492
      WBsf659850
      WBsf998259
      WBsf1018447
      WBsf229337
  Experimental_info: RNAi_result: WBRNAi00050803 Inferred_automatically: RNAi_primary
      WBRNAi00062589 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr3026
      Expr1013846
      Expr1032513
      Expr1154495
      Expr2016312
      Expr2034539
    Drives_construct: WBCnstr00011081
    Construct_product: WBCnstr00011081
    Microarray_results (19)
    Expression_cluster: WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044736:oscillating_dev_expression
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Spermatogenic
      WBPaper00045774:clk-1_downregulated
      WBPaper00045861:wdr-5(ok1417)_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00048923:Aging_regulated
      WBPaper00048988:daf-2(e1370)_downregulated_neuron
      WBPaper00048988:neuron_expressed
      WBPaper00049545:cco-1(RNAi)_upregulated
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00050370:dpy-21(e428)_L3_downregulated
      WBPaper00050412:cco-1(RNAi)_upregulated_N2
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050686:glp-1(e2141)_upregulated
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053302:alovudine_72h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053388:dauer_regulated_Cluster5
      WBPaper00053599:female_vs_male_downregulated
      WBPaper00053599:oocyte_vs_mitosis_upregulated
      WBPaper00053606:N2_vs_elt-2(ca15)_upregulated
      WBPaper00053810:nuo-6(qm200)_downregulated
      WBPaper00055013:hmg-3(bar24)_downregulated
      WBPaper00055354:Rapamycin_upregulated
      WBPaper00055482:pmt-2(RNAi)_downregulated
      WBPaper00055648:germline_expressed
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
      WBPaper00056290:hsp-6(mg585)_upregulated
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058969:RIS_depleted
      WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
      WBPaper00059567:olrn-1(ums9)_regulated
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:g1A
      WBPaper00061340:g1P
      WBPaper00061340:Seam_cell
      WBPaper00061527:srj-42-srw-113
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062446:nhr-8(hd117)_upregulated
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064532:pals-25(icb98)_downregulated
      WBPaper00064716:paraquat_upregulated
      WBPaper00065373:sek-1(km4)_upregulated_cisplatin
      WBPaper00065746:eat-2(ad1113)_downregulated
      WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2down
      WBPaper00041174:environmental
      WBPaper00041174:genotypic
      WBPaper00041174:genotypic_and_environmental
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00046853:AOBr_M.aeruginosa-batch-culture_downregulated
      WBPaper00047070:N2_starvation_downregulated
      WBPaper00047070:N2_UV_downregulated
      WBPaper00047070:xpa-1_UV_downregulated
    Interaction: WBInteraction000008513
      WBInteraction000008514
      WBInteraction000008515
      WBInteraction000008516
      WBInteraction000052148
      WBInteraction000052751
      WBInteraction000326994
      WBInteraction000425692
    WBProcess: WBbiopr:00000008
      WBbiopr:00000039
  Map_info: Map: IV Position: 6.37339 Error: 0.00679
    Positive: Positive_clone: M02B1 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: 2_point: 4986
        4987
      Multi_point: 1750
        1751
        2656
        4484
      Pos_neg_data: 4985
        7207
  Reference (50)
  Method: Gene