WormBase Tree Display for Gene: WBGene00001072

WBGene00001072 SMap: S_parent: Sequence: T14B4
  Identity: Version: 2
    Name: CGC_name: dpy-10 Person_evidence: WBPerson261
      Sequence_name: T14B4.7
      Molecular_name: T14B4.7
        T14B4.7.1
        CE51880
      Other_name: rol-7
        CELE_T14B4.7 Accession_evidence: NDB BX284602
      Public_name: dpy-10
    DB_info: Database: AceView gene 2H0
        WormQTL gene WBGene00001072
        WormFlux gene WBGene00001072
        NDB locus_tag CELE_T14B4.7
        Panther gene CAEEL|WormBase=WBGene00001072|UniProtKB=P35800
          family PTHR24637
        NCBI gene 36805042
        RefSeq protein NM_001348636.5
        SwissProt UniProtAcc P35800
        UniProt_GCRP UniProtAcc P35800
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:22 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 06 Mar 2018 14:35:46 WBPerson4025 Event: Split_into: WBGene00302993
      Split_into: WBGene00302993
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: dpy
    Reference_allele: WBVar00142982
    Allele (51)
    Possibly_affected_by: WBVar02152815
      WBVar02152872
      WBVar02157712
      WBVar02158431
      WBVar02158465
      WBVar02158466
      WBVar02158831
    Legacy_information: e128 : small dumpy (non-roller); sometimes poor freezing. ES3 (all stages) ME1. NA > 10 (e223 sc48 (left roller dumpy) sc30ts (left roller dumpy at 25x) sc? (pka rol-7) etc.).
      [C.elegansII] e128 : small dumpy (non-roller); sometimes poor survival from freezing; non-null. Suppresses some alleles of glp-1, emb-5.ES3 (all stages) ME1. OA>10: e223, sc48 (left roller dumpy), sc30ts (pka rol-7, left roller dumpy at 25C),cn64 (dominant left roller), q291, s364fdi etc.Cloned: encodes collagen 41% identical to DPY-2. e128 is splicing defect, cg36 (left roller dumpy, ochre, probable null). [Brenner 1974; Levy et al. 1993; CH]
    Strain (668)
    RNASeq_FPKM (74)
    GO_annotation (12)
    Contained_in_operon: CEOP5607
    Ortholog (22)
    Paralog (161)
    Structured_description: Concise_description: A cuticle collagen protein that afffects body morphology and movement and genetically interacts with the sqt-1 collagen gene. Paper_evidence: WBPaper00001792
          Curator_confirmed: WBPerson324
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to be a structural constituent of collagen and cuticulin-based cuticle. Involved in several processes, including cuticle development involved in collagen and cuticulin-based cuticle molting cycle; locomotion; and post-embryonic body morphogenesis. Predicted to be part of collagen trimer. Used to study skin disease. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Experimental_model: DOID:37 Homo sapiens Paper_evidence: WBPaper00061220
          Curator_confirmed: WBPerson324
          Date_last_updated: 02 May 2022 00:00:00
  Models_disease_asserted: WBDOannot00001178
  Molecular_info: Corresponding_CDS: T14B4.7
    Corresponding_CDS_history: T14B4.7:wp86
      T14B4.7a:wp257
      T14B4.7a:wp264
      T14B4.7b:wp97
      T14B4.7b:wp257
      T14B4.7c:wp264
    Corresponding_transcript: T14B4.7.1
    Corresponding_transcript_history: T14B4.7b:wp264
    Other_sequence: MHC07417_1
      MH05682
      PPC08679_1
    Associated_feature: WBsf650168
      WBsf650169
      WBsf665638
      WBsf223225
  Experimental_info: RNAi_result (35)
    Expr_pattern: Expr1022469
      Expr1030680
      Expr1156899
      Expr2011055
      Expr2029292
    Drives_construct: WBCnstr00037099
    Construct_product: WBCnstr00037099
    Regulate_expr_cluster: WBPaper00035873:dpy-10_regulated
    Microarray_results (26)
    Expression_cluster (274)
    Interaction: WBInteraction000000081
      WBInteraction000000202
      WBInteraction000000703
      WBInteraction000001621
      WBInteraction000001622
      WBInteraction000002683
      WBInteraction000003694
      WBInteraction000003697
      WBInteraction000004825
      WBInteraction000004826
      WBInteraction000007080
      WBInteraction000007470
      WBInteraction000008102
      WBInteraction000008103
      WBInteraction000008104
      WBInteraction000008105
      WBInteraction000008106
      WBInteraction000029578
      WBInteraction000029579
      WBInteraction000029580
      WBInteraction000029767
      WBInteraction000030341
      WBInteraction000052498
      WBInteraction000052505
      WBInteraction000052521
      WBInteraction000052522
      WBInteraction000052527
      WBInteraction000052528
      WBInteraction000052547
      WBInteraction000052548
      WBInteraction000052550
      WBInteraction000103404
      WBInteraction000103947
      WBInteraction000104493
      WBInteraction000104906
      WBInteraction000105012
      WBInteraction000105278
      WBInteraction000105975
      WBInteraction000106569
      WBInteraction000109601
      WBInteraction000110487
      WBInteraction000112818
      WBInteraction000115291
      WBInteraction000117932
      WBInteraction000118007
      WBInteraction000118309
      WBInteraction000119136
      WBInteraction000120114
      WBInteraction000121140
      WBInteraction000133915
      WBInteraction000135873
      WBInteraction000142422
      WBInteraction000142999
      WBInteraction000143439
      WBInteraction000143908
      WBInteraction000144486
      WBInteraction000148543
      WBInteraction000151735
      WBInteraction000152757
      WBInteraction000152970
      WBInteraction000160602
      WBInteraction000164807
      WBInteraction000165179
      WBInteraction000165781
      WBInteraction000165826
      WBInteraction000166203
      WBInteraction000168686
      WBInteraction000169014
      WBInteraction000172804
      WBInteraction000175195
      WBInteraction000175852
      WBInteraction000176220
      WBInteraction000178064
      WBInteraction000179235
      WBInteraction000182762
      WBInteraction000191305
      WBInteraction000193156
      WBInteraction000193158
      WBInteraction000193204
      WBInteraction000193441
      WBInteraction000193991
      WBInteraction000198195
      WBInteraction000205452
      WBInteraction000211128
      WBInteraction000211310
      WBInteraction000211734
      WBInteraction000212506
      WBInteraction000220199
      WBInteraction000223014
      WBInteraction000223840
      WBInteraction000226689
      WBInteraction000229267
      WBInteraction000229296
      WBInteraction000230046
      WBInteraction000234707
      WBInteraction000236739
      WBInteraction000240187
      WBInteraction000246281
      WBInteraction000247713
      WBInteraction000249895
      WBInteraction000252699
      WBInteraction000255513
      WBInteraction000256227
      WBInteraction000259767
      WBInteraction000262788
      WBInteraction000264377
      WBInteraction000266317
      WBInteraction000272986
      WBInteraction000282861
      WBInteraction000285345
      WBInteraction000285967
      WBInteraction000286401
      WBInteraction000286590
      WBInteraction000286751
      WBInteraction000291976
      WBInteraction000291987
      WBInteraction000295248
      WBInteraction000297243
      WBInteraction000300344
      WBInteraction000301074
      WBInteraction000303034
      WBInteraction000310538
      WBInteraction000315535
      WBInteraction000315772
      WBInteraction000317074
      WBInteraction000321630
      WBInteraction000322569
      WBInteraction000324987
      WBInteraction000325491
      WBInteraction000329396
      WBInteraction000329719
      WBInteraction000330350
      WBInteraction000333172
      WBInteraction000334986
      WBInteraction000335439
      WBInteraction000339255
      WBInteraction000342928
      WBInteraction000349866
      WBInteraction000353224
      WBInteraction000354094
      WBInteraction000363220
      WBInteraction000366220
      WBInteraction000368776
      WBInteraction000373531
      WBInteraction000373750
      WBInteraction000374079
      WBInteraction000376129
      WBInteraction000379722
      WBInteraction000382870
      WBInteraction000382923
      WBInteraction000389132
      WBInteraction000389573
      WBInteraction000394185
      WBInteraction000394227
      WBInteraction000396210
      WBInteraction000402901
      WBInteraction000408533
      WBInteraction000409600
      WBInteraction000423433
      WBInteraction000424491
      WBInteraction000425755
      WBInteraction000428105
      WBInteraction000432176
      WBInteraction000434368
      WBInteraction000441615
      WBInteraction000444886
      WBInteraction000446783
      WBInteraction000458175
      WBInteraction000459806
      WBInteraction000466873
      WBInteraction000470071
      WBInteraction000471353
      WBInteraction000474808
      WBInteraction000501295
      WBInteraction000501296
      WBInteraction000501357
      WBInteraction000501360
      WBInteraction000501361
      WBInteraction000501362
      WBInteraction000501363
      WBInteraction000501364
      WBInteraction000501365
      WBInteraction000501370
      WBInteraction000502443
      WBInteraction000517284
      WBInteraction000517285
      WBInteraction000519092
      WBInteraction000519098
      WBInteraction000525269
      WBInteraction000537307
      WBInteraction000571287
      WBInteraction000571289
      WBInteraction000571290
      WBInteraction000571573
      WBInteraction000579000
    WBProcess: WBbiopr:00000124
  Map_info: Map: II Position: 0
    Well_ordered
    Positive: Inside_rearr: mnDf40
        mC6
      Positive_clone: T14B4 Inferred_automatically: From sequence, transcript, pseudogene data
        ZK857
    Mapping_data: 2_point (51)
      Multi_point: 41
        45
        46
        47
        48
        49
        50
        51
        53
        54
        55
        56
        57
        206
        207
        208
        254
        273
        274
        319
        321
        323
        413
        437
        467
        468
        470
        475
        477
        485
        519
        521
        528
        537
        571
        591
        597
        631
        632
        633
        698
        699
        700
        701
        704
        706
        717
        721
        725
        726
        733
        736
        743
        745
        816
        817
        818
        819
        820
        823
        826
        828
        829
        830
        831
        836
        837
        838
        839
        840
        841
        844
        845
        847
        850
        851
        852
        853
        881
        882
        961
        1052
        1055
        1057
        1058
        1061
        1063
        1065
        1066
        1067
        1068
        1070
        1071
        1072
        1296
        1360
        1361
        1384
        1389
        1392
        1394
        1442
        1468
        1471
        1472
        1473
        1474
        1475
        1477
        1478
        1556
        1671
        1676
        1789
        2030
        2031
        2036
        2072
        2073
        2251
        2252
        2253
        2254
        2255
        2310
        2311
        2317
        2321
        2322
        2324
        2335
        2336
        2423
        2424
        2653
        2654
        2655
        2657
        2658
        2659
        2771
        2772
        2793
        2794
        2795
        3047
        3049
        3050
        3051
        3052
        3121
        3136
        3147
        3148
        3149
        3221
        3222
        3292
        3342
        3346
        3348
        3412
        3451
        3459
        3461
        3462
        3463
        3464
        3465
        3466
        3523
        3561
        3568
        3570
        3599
        3604
        3613
        3617
        3636
        3654
        3826
        3847
        3896
        3897
        3942
        3951
        4005
        4011
        4012
        4059
        4072
        4103
        4104
        4122
        4123
        4643
        4771
        5697
        5718
        5719
        5720
        5737
      Pos_neg_data (26)
    Landmark_gene
  Reference (203)
  Method: Gene