WormBase Tree Display for Gene: WBGene00003231

WBGene00003231 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: AH6
  Identity: Version: 1
    Name: CGC_name: mex-6 Person_evidence: WBPerson498
      Sequence_name: AH6.5
      Molecular_name: AH6.5
        AH6.5.1
        CE26846
      Other_name: CELE_AH6.5 Accession_evidence: NDB BX284602
      Public_name: mex-6
    DB_info: Database: AceView gene 2J815
        WormQTL gene WBGene00003231
        WormFlux gene WBGene00003231
        NDB locus_tag CELE_AH6.5
        Panther gene CAEEL|WormBase=WBGene00003231|UniProtKB=Q09436
          family PTHR12547
        NCBI gene 174504
        RefSeq protein NM_063642.7
        SwissProt UniProtAcc Q09436
        TREEFAM TREEFAM_ID TF322043
        UniProt_GCRP UniProtAcc Q09436
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:31 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: mex
    Allele (40)
    Legacy_information: [Priess, J./Plasterk,] pk440: Strain is viable, but enhances phenotype of maternal-effect lethal mutation mex-5(zu199). Embryos from mex-6(pk440);mex-5(zu199) hermaphrodites produce only hypodermis and muscle cell types.
    Strain: WBStrain00022453
      WBStrain00022485
      WBStrain00022487
    RNASeq_FPKM (74)
    GO_annotation (16)
    Ortholog (29)
    Paralog (20)
    Structured_description: Concise_description: mex-6 encodes a CCCH zinc-finger protein highly similar to MEX-5 that functions with MEX-5 to affect embryonic viability, establish soma germline asymmetry in embryos and establish PIE-1, MEX-1, and POS-1 asymmetry in embryos, and also affects formation of intestinal cells; MEX-6 and MEX-5 may act downstream of the PAR proteins. Paper_evidence: WBPaper00004540
            WBPaper00005160
            WBPaper00005654
          Curator_confirmed: WBPerson48
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Enables mRNA 3'-UTR binding activity; protein domain specific binding activity; and protein kinase binding activity. Involved in regulation of protein localization. Located in P granule. Expressed in AB; ABa; ABp; and germ line. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: AH6.5
    Corresponding_CDS_history: AH6.5:wp12
      AH6.5:wp43
    Corresponding_transcript: AH6.5.1
    Other_sequence: CGC00109_1
    Associated_feature: WBsf028078
      WBsf976539
      WBsf976540
      WBsf976541
      WBsf976542
      WBsf978799
      WBsf989072
      WBsf221892
      WBsf221893
    Transcription_factor: WBTranscriptionFactor000454
  Experimental_info: RNAi_result (68)
    Expr_pattern: Expr2463
      Expr4100
      Expr10817
      Expr1016913
      Expr1031528
      Expr1142831
      Expr2013544
      Expr2031778
    Drives_construct: WBCnstr00036173
      WBCnstr00039800
    Construct_product: WBCnstr00000077
      WBCnstr00005217
      WBCnstr00036173
      WBCnstr00039800
    Antibody: WBAntibody00000903
    Microarray_results (21)
    Expression_cluster (202)
    Interaction: WBInteraction000001059
      WBInteraction000001617
      WBInteraction000002645
      WBInteraction000002647
      WBInteraction000003836
      WBInteraction000006415
      WBInteraction000006868
      WBInteraction000006951
      WBInteraction000007179
      WBInteraction000007365
      WBInteraction000008554
      WBInteraction000008555
      WBInteraction000009032
      WBInteraction000029019
      WBInteraction000029038
      WBInteraction000029093
      WBInteraction000029094
      WBInteraction000029095
      WBInteraction000029096
      WBInteraction000031225
      WBInteraction000032499
      WBInteraction000052662
      WBInteraction000052810
      WBInteraction000101465
      WBInteraction000103648
      WBInteraction000104134
      WBInteraction000104624
      WBInteraction000104754
      WBInteraction000105004
      WBInteraction000105167
      WBInteraction000105236
      WBInteraction000105442
      WBInteraction000105698
      WBInteraction000105754
      WBInteraction000105853
      WBInteraction000105905
      WBInteraction000110227
      WBInteraction000110794
      WBInteraction000111115
      WBInteraction000112134
      WBInteraction000115018
      WBInteraction000115085
      WBInteraction000115286
      WBInteraction000116072
      WBInteraction000117724
      WBInteraction000118905
      WBInteraction000119290
      WBInteraction000119576
      WBInteraction000119784
      WBInteraction000119838
      WBInteraction000119901
      WBInteraction000122289
      WBInteraction000124207
      WBInteraction000124250
      WBInteraction000124412
      WBInteraction000124761
      WBInteraction000124951
      WBInteraction000125621
      WBInteraction000126670
      WBInteraction000126924
      WBInteraction000133278
      WBInteraction000134303
      WBInteraction000136577
      WBInteraction000137155
      WBInteraction000137271
      WBInteraction000137730
      WBInteraction000138044
      WBInteraction000138137
      WBInteraction000138865
      WBInteraction000139948
      WBInteraction000142981
      WBInteraction000143142
      WBInteraction000143248
      WBInteraction000144077
      WBInteraction000144117
      WBInteraction000147268
      WBInteraction000149178
      WBInteraction000151140
      WBInteraction000152093
      WBInteraction000152638
      WBInteraction000152767
      WBInteraction000156933
      WBInteraction000157311
      WBInteraction000160364
      WBInteraction000163998
      WBInteraction000164571
      WBInteraction000165139
      WBInteraction000165140
      WBInteraction000166103
      WBInteraction000168622
      WBInteraction000170239
      WBInteraction000170496
      WBInteraction000170705
      WBInteraction000171101
      WBInteraction000171422
      WBInteraction000171505
      WBInteraction000172004
      WBInteraction000176133
      WBInteraction000176883
      WBInteraction000177210
      WBInteraction000180416
      WBInteraction000181994
      WBInteraction000182094
      WBInteraction000183413
      WBInteraction000183568
      WBInteraction000183591
      WBInteraction000184291
      WBInteraction000184445
      WBInteraction000184973
      WBInteraction000186821
      WBInteraction000187326
      WBInteraction000190140
      WBInteraction000191099
      WBInteraction000192184
      WBInteraction000192889
      WBInteraction000193700
      WBInteraction000194124
      WBInteraction000194364
      WBInteraction000195803
      WBInteraction000196339
      WBInteraction000197236
      WBInteraction000197690
      WBInteraction000199890
      WBInteraction000200036
      WBInteraction000202892
      WBInteraction000203183
      WBInteraction000203302
      WBInteraction000203499
      WBInteraction000203661
      WBInteraction000205051
      WBInteraction000207079
      WBInteraction000208071
      WBInteraction000211622
      WBInteraction000211710
      WBInteraction000211773
      WBInteraction000214528
      WBInteraction000214970
      WBInteraction000215747
      WBInteraction000217481
      WBInteraction000218577
      WBInteraction000220258
      WBInteraction000223974
      WBInteraction000224006
      WBInteraction000225010
      WBInteraction000226182
      WBInteraction000226409
      WBInteraction000227311
      WBInteraction000227367
      WBInteraction000229709
      WBInteraction000230231
      WBInteraction000231423
      WBInteraction000232232
      WBInteraction000234315
      WBInteraction000235775
      WBInteraction000236997
      WBInteraction000237017
      WBInteraction000237193
      WBInteraction000237789
      WBInteraction000238057
      WBInteraction000240133
      WBInteraction000241223
      WBInteraction000245069
      WBInteraction000245489
      WBInteraction000246035
      WBInteraction000246306
      WBInteraction000246794
      WBInteraction000249783
      WBInteraction000249992
      WBInteraction000251103
      WBInteraction000252115
      WBInteraction000254395
      WBInteraction000256301
      WBInteraction000257867
      WBInteraction000258114
      WBInteraction000259164
      WBInteraction000259677
      WBInteraction000260802
      WBInteraction000262042
      WBInteraction000263322
      WBInteraction000263325
      WBInteraction000264557
      WBInteraction000266065
      WBInteraction000268877
      WBInteraction000270151
      WBInteraction000270468
      WBInteraction000271178
      WBInteraction000272610
      WBInteraction000274392
      WBInteraction000276821
      WBInteraction000276835
      WBInteraction000279942
      WBInteraction000281000
      WBInteraction000281174
      WBInteraction000281271
      WBInteraction000282571
      WBInteraction000283162
      WBInteraction000283443
      WBInteraction000283557
      WBInteraction000283818
      WBInteraction000286073
      WBInteraction000289116
      WBInteraction000291115
      WBInteraction000291612
      WBInteraction000291724
      WBInteraction000293368
      WBInteraction000296113
      WBInteraction000296540
      WBInteraction000297562
      WBInteraction000298160
      WBInteraction000299076
      WBInteraction000303553
      WBInteraction000303999
      WBInteraction000304041
      WBInteraction000307970
      WBInteraction000308003
      WBInteraction000308974
      WBInteraction000313020
      WBInteraction000314662
      WBInteraction000314771
      WBInteraction000315053
      WBInteraction000315271
      WBInteraction000316040
      WBInteraction000316365
      WBInteraction000316405
      WBInteraction000316711
      WBInteraction000317837
      WBInteraction000322910
      WBInteraction000323646
      WBInteraction000324750
      WBInteraction000326174
      WBInteraction000332004
      WBInteraction000334872
      WBInteraction000336501
      WBInteraction000337544
      WBInteraction000337732
      WBInteraction000337986
      WBInteraction000342156
      WBInteraction000343993
      WBInteraction000347038
      WBInteraction000348397
      WBInteraction000351113
      WBInteraction000351715
      WBInteraction000352079
      WBInteraction000354594
      WBInteraction000356143
      WBInteraction000357725
      WBInteraction000357883
      WBInteraction000360050
      WBInteraction000360546
      WBInteraction000360894
      WBInteraction000363142
      WBInteraction000363326
      WBInteraction000363546
      WBInteraction000364795
      WBInteraction000366441
      WBInteraction000367126
      WBInteraction000367938
      WBInteraction000370338
      WBInteraction000372649
      WBInteraction000373804
      WBInteraction000374355
      WBInteraction000374454
      WBInteraction000374586
      WBInteraction000374916
      WBInteraction000379004
      WBInteraction000380110
      WBInteraction000380494
      WBInteraction000381108
      WBInteraction000381348
      WBInteraction000383155
      WBInteraction000383694
      WBInteraction000384225
      WBInteraction000384226
      WBInteraction000384227
      WBInteraction000385176
      WBInteraction000385993
      WBInteraction000386188
      WBInteraction000390779
      WBInteraction000393046
      WBInteraction000398355
      WBInteraction000399237
      WBInteraction000400454
      WBInteraction000404190
      WBInteraction000404581
      WBInteraction000406793
      WBInteraction000411009
      WBInteraction000412878
      WBInteraction000415750
      WBInteraction000416692
      WBInteraction000427288
      WBInteraction000432271
      WBInteraction000435062
      WBInteraction000435283
      WBInteraction000440728
      WBInteraction000442744
      WBInteraction000442867
      WBInteraction000446182
      WBInteraction000446561
      WBInteraction000446599
      WBInteraction000448870
      WBInteraction000449918
      WBInteraction000450127
      WBInteraction000451071
      WBInteraction000451460
      WBInteraction000458911
      WBInteraction000460389
      WBInteraction000460671
      WBInteraction000460817
      WBInteraction000460867
      WBInteraction000461207
      WBInteraction000462291
      WBInteraction000501416
      WBInteraction000501770
      WBInteraction000501774
      WBInteraction000503053
      WBInteraction000503442
      WBInteraction000503529
      WBInteraction000503534
      WBInteraction000513022
      WBInteraction000513032
      WBInteraction000513042
      WBInteraction000513043
      WBInteraction000513044
      WBInteraction000513051
      WBInteraction000513059
      WBInteraction000513060
      WBInteraction000513069
      WBInteraction000513073
      WBInteraction000513075
      WBInteraction000515557
      WBInteraction000515562
      WBInteraction000515613
      WBInteraction000515614
      WBInteraction000515620
      WBInteraction000517471
      WBInteraction000520750
      WBInteraction000522966
      WBInteraction000523102
      WBInteraction000523103
      WBInteraction000523104
      WBInteraction000523105
      WBInteraction000525195
      WBInteraction000526283
      WBInteraction000526667
      WBInteraction000526668
      WBInteraction000527285
      WBInteraction000527615
      WBInteraction000530530
      WBInteraction000531730
      WBInteraction000533656
      WBInteraction000541654
      WBInteraction000541655
      WBInteraction000549118
      WBInteraction000550333
      WBInteraction000551341
      WBInteraction000554919
      WBInteraction000554922
      WBInteraction000554923
      WBInteraction000558174
      WBInteraction000558177
      WBInteraction000559006
      WBInteraction000562868
      WBInteraction000580158
      WBInteraction000582460
      WBInteraction000583047
    WBProcess: WBbiopr:00000017
  Map_info (4)
  Reference (58)
  Remark: Sequence analysis of the mex-6(pk440) allele showed that bases 12737- 15477 corresponding to the AH6 cosmid were deleted. This work was done in the lab of Ron Plasterk.
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene