[Jim Thomas] Defecation defective, moderate to severe constipation, expulsion muscle contraction (Exp) missing in about 9 of 10 defecation cycles, anterior body contraction (aBoc) usually missing as well, adult males unaffected and mate well.
See also sa23, sa41, sa42, sa43
[C.elegansII] sa23 : defecation defective, moderate to severe constipation, expulsion muscle contraction (Exp) missing in about 9 of 10 defecation cycles, anterior body contraction (aBoc) usually missing as well, adult males unaffected and mate well. OA3: sa41, sa42, sa43 (all similar) [Thomas 1990; JT]
an ortholog of calcium-dependent serine endoproteinases, the kex2/subtilisin-like proprotein convertase that affects defecation cycle and anterior body contractions; and is expressed in all muscle cells except pharyngeal muscles.
Enables serine-type endopeptidase activity. Involved in several processes, including neuropeptide processing; positive regulation of synaptic assembly at neuromuscular junction; and positive regulation of transport. Located in extracellular space.