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WormBase Tree Display for Gene: WBGene00000063

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Name Class

WBGene00000063SMapS_parentSequenceT04C12
IdentityVersion1
NameCGC_nameact-1Person_evidenceWBPerson259
Sequence_nameT04C12.6
Molecular_nameT04C12.6
T04C12.6.1
CE13148
Other_nameCELE_T04C12.6Accession_evidenceNDBBX284605
Public_nameact-1
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:19WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classact
Allele (13)
StrainWBStrain00033488
In_clusteract-123
RNASeq_FPKM (74)
GO_annotation (17)
Ortholog (46)
ParalogWBGene00000064Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
WBGene00000065Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00000066Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00022774Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00000067Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00000199Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00016793Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00013168Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00007434Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00018349Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00000200Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionact-1 encodes an actin isoform that is required for proper body wall muscle and pharyngeal muscle structures and the motility of animals; actins have highly similar amino acid sequences; ACT-1 is identical to ACT-3; act-1 functions redundantly with two other actin isoforms, act-2 and act-3, to control cytoplasmic microfilament function in the early embryo.Paper_evidenceWBPaper00001178
WBPaper00014413
WBPaper00027028
Curator_confirmedWBPerson324
Date_last_updated29 Mar 2007 00:00:00
Automated_descriptionPredicted to be a structural constituent of cytoskeleton. Involved in cortical actin cytoskeleton organization; embryo development; and mitotic cytokinesis. Located in striated muscle thin filament. Expressed in body wall musculature and gonad. Human ortholog(s) of this gene implicated in several diseases, including Baraitser-Winter syndrome 1; Baraitser-Winter syndrome 2; and autosomal dominant nonsyndromic deafness 20. Is an ortholog of human ACTB (actin beta).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:1588Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:132)
DOID:0081113Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:144)
DOID:10881Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:132)
DOID:0081112Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:132)
DOID:0110550Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:144)
Molecular_infoCorresponding_CDST04C12.6
Corresponding_transcriptT04C12.6.1
Other_sequence (456)
Associated_featureWBsf647226
WBsf647227
WBsf661678
WBsf661679
WBsf1001264
WBsf1001265
WBsf1020400
WBsf232452
WBsf232453
WBsf232454
Experimental_infoRNAi_result (55)
Expr_patternExpr558
Expr2793
Expr4555
Expr9252
Expr1030024
Expr1156000
Expr2009221
Expr2027458
Drives_constructWBCnstr00006031
WBCnstr00006032
WBCnstr00013852
WBCnstr00037760
Construct_productWBCnstr00015675
WBCnstr00015678
WBCnstr00037760
WBCnstr00038658
AntibodyWBAntibody00001783
Microarray_resultsSMD_T04C12.6
GPL19516_CGZ0033111
GPL19516_CGZ0033112
GPL19516_CGZ0033113
GPL19516_CGZ0033114
GPL21109_T04C12.6.1
GPL8304_CE_WBGene00000063_B
GPL9450_T04C12.6
cea2.c.38095
Expression_cluster (171)
Interaction (326)
WBProcessWBbiopr:00000096
Map_infoMapVPosition2.94475Error0.000513
PositivePositive_cloneT04C12Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00000608
WBPaper00000611
WBPaper00000741
WBPaper00000742
WBPaper00000785
WBPaper00000798
WBPaper00000801
WBPaper00000969
WBPaper00001090
WBPaper00001178
WBPaper00001230
WBPaper00001262
WBPaper00001401
WBPaper00001412
WBPaper00001521
WBPaper00001560
WBPaper00001567
WBPaper00001571
WBPaper00001642
WBPaper00001667
WBPaper00001671
WBPaper00001686
WBPaper00001692
WBPaper00001709
WBPaper00001744
WBPaper00001761
WBPaper00001813
WBPaper00001824
WBPaper00001895
WBPaper00001912
WBPaper00002044
WBPaper00002305
WBPaper00002748
WBPaper00003410
WBPaper00004326
WBPaper00005055
WBPaper00005943
WBPaper00006387
WBPaper00006429
WBPaper00013773
WBPaper00013841
WBPaper00013842
WBPaper00013855
WBPaper00013992
WBPaper00014087
WBPaper00014145
WBPaper00014204
WBPaper00014205
WBPaper00014218
WBPaper00014311
WBPaper00014413
WBPaper00014490
WBPaper00014646
WBPaper00014753
WBPaper00014851
WBPaper00015604
WBPaper00016019
WBPaper00016417
WBPaper00016420
WBPaper00020963
WBPaper00022040
WBPaper00024200
WBPaper00025088
WBPaper00025171
WBPaper00025227
WBPaper00027028
WBPaper00029197
WBPaper00029334
WBPaper00031353
WBPaper00031448
WBPaper00032009
WBPaper00032287
WBPaper00035956
WBPaper00038491
WBPaper00039517
WBPaper00040301
WBPaper00040903
WBPaper00042178
WBPaper00042592
WBPaper00049531
WBPaper00049595
WBPaper00049828
WBPaper00050403
WBPaper00054920
WBPaper00055090
WBPaper00056474
WBPaper00056595
WBPaper00057312
WBPaper00059765
WBPaper00060487
WBPaper00060797
WBPaper00060896
WBPaper00061939
WBPaper00061940
WBPaper00062110
WBPaper00062405
WBPaper00064306
WBPaper00064804
WBPaper00064904
WBPaper00064917
WBPaper00064942
WBPaper00065201
WBPaper00065636
WBPaper00065667
WBPaper00065712
WBPaper00066025
RemarkT04C12.4 changed to T04C12.6. email from JAH 0109
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene