WormBase Tree Display for Gene: RGD:2661
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| RGD:2661 | Identity | Name | CGC_name | Gapdh | Inferred_automatically | AGR_import |
|---|---|---|---|---|---|---|
| Public_name | Gapdh | |||||
| DB_info | Database | RGD | id | 2661 | ||
| AGR | cURI | RGD:2661 | ||||
| EnsEMBL | ENSEMBL_geneID | ENSRNOG00000018630 | ||||
| UniProt | UniProt_AC | P04797 | ||||
| Species | Rattus norvegicus | |||||
| Status | Live | |||||
| Gene_info | Biotype | SO:0001217 | ||||
| Ortholog | WBGene00001686 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | ||
| Hieranoid | ||||||
| Inparanoid | ||||||
| OMA | ||||||
| OrthoFinder | ||||||
| OrthoInspector | ||||||
| Panther | ||||||
| PhylomeDB | ||||||
| SonicParanoid | ||||||
| WBGene00001683 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | |||
| Hieranoid | ||||||
| Inparanoid | ||||||
| OMA | ||||||
| OrthoFinder | ||||||
| OrthoInspector | ||||||
| Panther | ||||||
| PhylomeDB | ||||||
| SonicParanoid | ||||||
| WBGene00001685 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | |||
| Hieranoid | ||||||
| Inparanoid | ||||||
| OMA | ||||||
| OrthoFinder | ||||||
| OrthoInspector | ||||||
| Panther | ||||||
| PhylomeDB | ||||||
| SonicParanoid | ||||||
| WBGene00001684 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | |||
| Hieranoid | ||||||
| Inparanoid | ||||||
| OMA | ||||||
| OrthoFinder | ||||||
| OrthoInspector | ||||||
| Panther | ||||||
| PhylomeDB | ||||||
| SonicParanoid | ||||||
| Structured_description | Automated_description | Enables several functions, including glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity; identical protein binding activity; and peptidyl-cysteine S-nitrosylase activity. Involved in several processes, including gluconeogenesis; negative regulation of vascular associated smooth muscle cell apoptotic process; and second-messenger-mediated signaling. Located in cytosol; microtubule cytoskeleton; and nucleus. Is active in glutamatergic synapse and postsynaptic density, intracellular component. Used to study Alzheimer's disease and middle cerebral artery infarction. Biomarker of several diseases, including brain glioma; diabetic retinopathy; obesity; oral squamous cell carcinoma; and rheumatic heart disease. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human GAPDH (glyceraldehyde-3-phosphate dehydrogenase); PARTICIPATES IN gluconeogenesis pathway; electron transport chain pathway; Fanconi syndrome pathway; INTERACTS WITH (-)-selegiline; 1,3-dinitrobenzene; 17alpha-ethynylestradiol. | Inferred_automatically | AGR_import |
