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WormBase Tree Display for Gene: WBGene00000509

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Name Class

WBGene00000509EvidencePaper_evidenceWBPaper00005916
SMapS_parentSequenceC28D4
IdentityVersion1
NameCGC_namecka-1
Sequence_nameC28D4.2
Molecular_nameC28D4.2a
C28D4.2a.1
CE20533
C28D4.2b
CE08431
C28D4.2c
CE49764
C28D4.2b.1
C28D4.2c.1
Other_nameCELE_C28D4.2Accession_evidenceNDBBX284604
Public_namecka-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcka
Allele (53)
RNASeq_FPKM (74)
GO_annotation (11)
Ortholog (38)
ParalogWBGene00000515Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00000510Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00000512Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00000513Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00000511Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00000514Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
Structured_descriptionConcise_descriptioncka-1 encodes an isoform of choline kinase whose activity has beenverified in vitro, and that has a strong preference for choline overethanolamine; CKA-1 and CKA-2 comprise a related group ('A') of cholinekinases.Paper_evidenceWBPaper00005916
Curator_confirmedWBPerson567
Date_last_updated11 Aug 2006 00:00:00
Automated_descriptionEnables choline kinase activity. Involved in CDP-choline pathway. Located in cell cortex. Human ortholog(s) of this gene implicated in several diseases, including colon adenoma; megaconial type congenital muscular dystrophy; narcolepsy; and recurrent hypersomnia. Is an ortholog of human CHKA (choline kinase alpha) and CHKB (choline kinase beta).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:8619Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:1938)
DOID:8986Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:1938)
DOID:0050912Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:1937)
DOID:9884Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:1938)
DOID:0110632Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:1938)
DOID:1059Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:1938)
Molecular_infoCorresponding_CDSC28D4.2a
C28D4.2b
C28D4.2c
Corresponding_transcriptC28D4.2a.1
C28D4.2b.1
C28D4.2c.1
Other_sequence (59)
Associated_featureWBsf652081
WBsf668182
WBsf668183
WBsf668184
WBsf668185
WBsf997468
WBsf1017993
WBsf230606
Experimental_infoRNAi_resultWBRNAi00083992Inferred_automaticallyRNAi_primary
WBRNAi00102564Inferred_automaticallyRNAi_primary
WBRNAi00041408Inferred_automaticallyRNAi_primary
WBRNAi00084001Inferred_automaticallyRNAi_primary
WBRNAi00084002Inferred_automaticallyRNAi_primary
WBRNAi00029298Inferred_automaticallyRNAi_primary
WBRNAi00011298Inferred_automaticallyRNAi_primary
Expr_patternExpr1024344
Expr1030302
Expr1145439
Expr2010024
Expr2028265
Drives_constructWBCnstr00013306
WBCnstr00037489
Construct_productWBCnstr00013306
WBCnstr00037489
AntibodyWBAntibody00000358
Microarray_results (21)
Expression_cluster (105)
Interaction (24)
Map_infoMapIVPosition4.39455Error0.001437
PositivePositive_cloneC28D4Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point5022
Pseudo_map_position
ReferenceWBPaper00005493
WBPaper00005916
WBPaper00034497
WBPaper00038491
WBPaper00040386
WBPaper00042257
WBPaper00055090
WBPaper00064661
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene