WormBase Tree Display for Gene: WBGene00001950
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| WBGene00001950 | SMap | S_parent | Sequence | T24B8 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | hlh-3 | Person_evidence | WBPerson346 | |||||
| Sequence_name | T24B8.6 | ||||||||
| Molecular_name | T24B8.6 | ||||||||
| T24B8.6.1 | |||||||||
| CE42887 | |||||||||
| Other_name | CELE_T24B8.6 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | hlh-3 | ||||||||
| DB_info | Database | AceView | gene | 2J377 | |||||
| WormQTL | gene | WBGene00001950 | |||||||
| WormFlux | gene | WBGene00001950 | |||||||
| NDB | locus_tag | CELE_T24B8.6 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00001950|UniProtKB=Q22717 | |||||||
| family | PTHR13935 | ||||||||
| NCBI | gene | 174447 | |||||||
| RefSeq | protein | NM_063537.9 | |||||||
| SwissProt | UniProtAcc | Q22717 | |||||||
| TREEFAM | TREEFAM_ID | TF322889 | |||||||
| UniProt_GCRP | UniProtAcc | Q22717 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | hlh | ||||||||
| Allele (26) | |||||||||
| Possibly_affected_by | WBVar02153192 | ||||||||
| Strain | WBStrain00029568 | ||||||||
| WBStrain00028725 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (25) | |||||||||
| Ortholog (31) | |||||||||
| Paralog | WBGene00001952 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00001958 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00001951 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | hlh-3 encodes a basic helix-loop-helix transcription factor homologous to Drosophila Achaete-scute; in vitro, HLH-3 can heterodimerize, and bind an E-box-containing probe, with HLH-2, the C. elegans E/daughterless ortholog with which it is coexpressed in the nuclei of embryonic neuronal precursors. | Paper_evidence | WBPaper00002826 | |||||
| WBPaper00011689 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and protein heterodimerization activity. Contributes to RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including regulation of axon extension involved in axon guidance; regulation of egg-laying behavior; and response to food. Located in nucleus. Part of RNA polymerase II transcription regulator complex. Expressed in several structures, including AB lineage cell; ABplapppapp; ABplpapaaa; nerve ring; and neurons. Is an ortholog of human ASCL1 (achaete-scute family bHLH transcription factor 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | T24B8.6 | |||||||
| Corresponding_CDS_history | T24B8.6:wp193 | ||||||||
| Corresponding_transcript | T24B8.6.1 | ||||||||
| Other_sequence | Dviv_isotig09110 | ||||||||
| Dviv_isotig09108 | |||||||||
| CBC06129_1 | |||||||||
| Dviv_isotig09109 | |||||||||
| Associated_feature | WBsf978509 | ||||||||
| WBsf988933 | |||||||||
| WBsf988934 | |||||||||
| WBsf1012801 | |||||||||
| WBsf221847 | |||||||||
| Gene_product_binds | WBsf019110 | ||||||||
| WBsf019111 | |||||||||
| WBsf019112 | |||||||||
| WBsf019113 | |||||||||
| WBsf919547 | |||||||||
| WBsf919549 | |||||||||
| WBsf919551 | |||||||||
| WBsf919553 | |||||||||
| Transcription_factor | WBTranscriptionFactor000064 | ||||||||
| WBTranscriptionFactor000081 | |||||||||
| Experimental_info | RNAi_result (18) | ||||||||
| Expr_pattern (12) | |||||||||
| Drives_construct (11) | |||||||||
| Construct_product | WBCnstr00013153 | ||||||||
| WBCnstr00016007 | |||||||||
| WBCnstr00021047 | |||||||||
| WBCnstr00022538 | |||||||||
| WBCnstr00036568 | |||||||||
| WBCnstr00041174 | |||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (128) | |||||||||
| Interaction (234) | |||||||||
| Map_info | Map | II | Position | 1.00181 | Error | 0.005012 | |||
| Positive | Positive_clone | LG11.1 | |||||||
| T24B8 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||||
| Mapping_data | Multi_point | 5491 | |||||||
| 4337 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (47) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
