WormBase Tree Display for Gene: WBGene00012832
expand all nodes | collapse all nodes | view schema
WBGene00012832 | SMap | S_parent | Sequence | Y43F8C | |||
---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||
Name | CGC_name | dmd-3 | Person_evidence | WBPerson1375 | |||
Sequence_name | Y43F8C.10 | ||||||
Molecular_name | Y43F8C.10a | ||||||
Y43F8C.10a.1 | |||||||
CE39835 | |||||||
Y43F8C.10b | |||||||
CE44151 | |||||||
Y43F8C.10b.1 | |||||||
Other_name | CELE_Y43F8C.10 | Accession_evidence | NDB | BX284605 | |||
Public_name | dmd-3 | ||||||
DB_info | Database | AceView | gene | 5U124 | |||
WormQTL | gene | WBGene00012832 | |||||
WormFlux | gene | WBGene00012832 | |||||
NDB | locus_tag | CELE_Y43F8C.10 | |||||
Panther | gene | CAEEL|WormBase=WBGene00012832|UniProtKB=Q9XWN9 | |||||
family | PTHR12322 | ||||||
NCBI | gene | 189878 | |||||
RefSeq | protein | NM_001269953.2 | |||||
NM_001269954.4 | |||||||
SwissProt | UniProtAcc | Q9XWN9 | |||||
UniProt_GCRP | UniProtAcc | Q9XWN9 | |||||
Species | Caenorhabditis elegans | ||||||
History | Version_change (2) | ||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | dmd | ||||||
Allele (137) | |||||||
Strain | WBStrain00031959 | ||||||
WBStrain00029935 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (30) | |||||||
Ortholog (33) | |||||||
Paralog | WBGene00003100 | Caenorhabditis elegans | From_analysis | Panther | |||
WormBase-Compara | |||||||
WBGene00003114 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00007058 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00007929 | Caenorhabditis elegans | From_analysis | Panther | ||||
WBGene00022060 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00019521 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00020708 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00017326 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00007776 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
Structured_description | Concise_description | dmd-3 encodes a transcription factor with two DNA-binding Zn finger DM domains that is homologous to vertebrate dmrt-1 (OMIM:154230); dmd-3 is necessary for male-specific morphogenesis of the tail tip; dmd-3 acts with mab-3 to coordinate both tail tip cell fusion and retraction; dmd-3::YFP was expressed in a number of sexually dimorphic or sex-specific cells, including the tail tip, hindgut, B lineage, ray RnA neurons and somatic gonad; dmd-3 expression parallels tail tip remodeling, consistent with a cell autonomous, instructive role for dmd-3 in the control of morphogenesis; dmd-3 is a direct target of repression by TRA-1A in hermaphrodite tail tip and hindgut; sexually dimorphic dmd-3 expression determines the sexual specificity of tail tip morphogenesis; tail tip dmd-3 expression is regulated in an initial Wnt-independent induction of dmd-3, followed by Wnt-dependent maintenance and amplification; maintenance phase expression of dmd-3 requires lin-44 and tlp-1. | Paper_evidence | WBPaper00031953 | |||
WBPaper00038232 | |||||||
Curator_confirmed | WBPerson12884 | ||||||
Date_last_updated | 02 Jun 2011 00:00:00 | ||||||
Automated_description | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including nematode male tail tip morphogenesis; neuron differentiation; and regulation of reproductive process. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in neuronal cell body. Expressed in several structures, including PHC; epithelial cell; gonad; ray neuron type A; and tail hypodermis. Is an ortholog of human DMRTB1 (DMRT like family B with proline rich C-terminal 1). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | Y43F8C.10a | |||||
Y43F8C.10b | |||||||
Corresponding_CDS_history | Y43F8C.10:wp154 | ||||||
Corresponding_transcript | Y43F8C.10a.1 | ||||||
Y43F8C.10b.1 | |||||||
Other_sequence (32) | |||||||
Associated_feature | WBsf653584 | ||||||
WBsf978455 | |||||||
WBsf1003327 | |||||||
WBsf1003328 | |||||||
WBsf1003329 | |||||||
WBsf1003330 | |||||||
WBsf1021795 | |||||||
WBsf1021796 | |||||||
WBsf1021797 | |||||||
WBsf1021798 | |||||||
Transcription_factor | WBTranscriptionFactor000791 | ||||||
Experimental_info | RNAi_result | WBRNAi00092994 | Inferred_automatically | RNAi_primary | |||
WBRNAi00019982 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00056519 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00077518 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr8158 | ||||||
Expr14446 | |||||||
Expr14652 | |||||||
Expr1025148 | |||||||
Expr1159992 | |||||||
Expr2010954 | |||||||
Expr2029193 | |||||||
Drives_construct | WBCnstr00000509 | ||||||
WBCnstr00000513 | |||||||
WBCnstr00013145 | |||||||
Construct_product | WBCnstr00000512 | ||||||
WBCnstr00000513 | |||||||
WBCnstr00000515 | |||||||
Microarray_results (21) | |||||||
Expression_cluster (69) | |||||||
Interaction (98) | |||||||
Map_info | Map | V | Position | 22.6873 | Error | 0.033316 | |
Positive | Positive_clone | Y43F8C | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Mapping_data | Multi_point | 5352 | |||||
Pseudo_map_position | |||||||
Reference (33) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |