WormBase Tree Display for Interaction: WBInteraction000517843
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| WBInteraction000517843 | Interaction_type | Regulatory | Change_of_localization | ||
|---|---|---|---|---|---|
| Change_of_expression_level | |||||
| Interactor | Interactor_overlapping_gene | WBGene00004457 | Interactor_type | Trans_regulated | |
| Expr_pattern | Expr5089 | ||||
| Transgene | WBTransgene00000717 | ||||
| Construct | WBCnstr00000713 | ||||
| WBGene00003803 | Interactor_type | Trans_regulator | |||
| Variation_interactor | WBVar00251617 | Interactor_type | Trans_regulator | ||
| Interaction_summary | In wild-type or rae-1+/-animals, RPM-1::GFP is localized to perisynaptic puncta in many neurons, and our analysis specifically focused on the nerve ring, the dorsal cord, and the SAB neurons. In rae-1-/- animals, we observed no change in the punc- tate localization or in the levels of RPM-1::GFP in the nerve ring, dorsal nerve cord, or the SAB neurons. These results demonstrate that rae-1 is not required for localization of RPM-1, and are consistent with rae-1 functioning down- stream of rpm-1. | ||||
| Detection_method | Construct | ||||
| Reporter_gene | [rpm-1::gfp] | ||||
| Transgene | |||||
| Regulation_level | Post_translational | ||||
| Regulation_result | Does_not_regulate | Anatomy_term | WBbt:0006749 | ||
| WBbt:0006750 | |||||
| WBbt:0005396 | |||||
| Subcellular_localization | perisynaptic puncta | ||||
| Paper | WBPaper00040910 |
