WormBase Tree Display for Variation: WBVar00143246

WBVar00143246 Name: Public_name: e491
  Sequence_details: SeqStatus: Pending_curation
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain (12)
    Laboratory: CB
    Status: Live
  Affects: Gene: WBGene00004857
    Interactor: WBInteraction000521783
      WBInteraction000541128
      WBInteraction000555704
  Genetics: Mapping_data: In_2_point: 64
        482
        6038
        6040
      In_multi_point: 87
        377
        501
        522
        866
        867
        1090
        1093
        1094
        1095
        1096
        1099
        1100
        1102
        1110
        1397
        1398
        1400
        1401
        1404
        1415
        1417
        1482
        1483
        1484
        1486
        1488
        1494
        1502
        1665
        1667
        1722
        1725
        1903
        1904
        1906
        1907
        2057
        2058
        2077
        2080
        2130
        2217
        3168
        3170
        3192
        3300
        3301
        3302
        3305
        3306
      In_pos_neg_data: 1613
        1614
        1615
    Marked_rearrangement: eT1[sma-3(e491)]
  Description: Phenotype: WBPhenotype:0000016 Paper_evidence: WBPaper00031872
        Curator_confirmed: WBPerson712
        Remark: % animals paralyzed after 60 min on 1mM aldicarb was significantly higher than % N2 animals paralyzed. Paper_evidence: WBPaper00031872
            Curator_confirmed: WBPerson712
        Affected_by: Molecule: WBMol:00003650 Paper_evidence: WBPaper00031872
              Curator_confirmed: WBPerson712
        EQ_annotations: Anatomy_term: WBbt:0007833 PATO:0001549 Paper_evidence: WBPaper00031872
                Curator_confirmed: WBPerson712
      WBPhenotype:0000070 Paper_evidence: WBPaper00004199
        Curator_confirmed: WBPerson551
      WBPhenotype:0000164 Paper_evidence: WBPaper00043908
        Curator_confirmed: WBPerson2987
      WBPhenotype:0000229 Paper_evidence: WBPaper00000031
          WBPaper00003454
          WBPaper00004199
          WBPaper00002374
        Curator_confirmed: WBPerson48
          WBPerson712
          WBPerson551
      WBPhenotype:0000296 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: males have crumpled spicules Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0000297 Paper_evidence: WBPaper00001328
          WBPaper00002374
        Curator_confirmed: WBPerson712
          WBPerson551
        Remark: Table 1 Paper_evidence: WBPaper00002374
            Curator_confirmed: WBPerson551
        EQ_annotations: Anatomy_term: WBbt:0006941 PATO:0000460 Paper_evidence: WBPaper00001328
                Curator_confirmed: WBPerson712
          Life_stage: WBls:0000056 PATO:0000460 Paper_evidence: WBPaper00001328
                Curator_confirmed: WBPerson712
        Phenotype_assay: Temperature: 20C Paper_evidence: WBPaper00001328
              Curator_confirmed: WBPerson712
          Genotype: him-5(e1490) Paper_evidence: WBPaper00001328
              Curator_confirmed: WBPerson712
      WBPhenotype:0000324 Paper_evidence: WBPaper00032064
          WBPaper00043908
        Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
          WBPerson2987
        Remark: Mean length was 214.3 2.9um (n=25) compared to 252.9 3.1 um for wild type. As determined by high-resolution, lensless, optofluidic microscopy method (OFM)-based on-chip microscopy. Paper_evidence: WBPaper00032064
            Curator_confirmed: WBPerson712
        Ease_of_scoring: ES3_Easy_to_score (2)
      WBPhenotype:0000420 Paper_evidence: WBPaper00031872
        Curator_confirmed: WBPerson712
        Remark: % animals paralyzed after 60 min on 200mM levamisole is significantly higher than % N2 animals paralyzed under same conditions. Paper_evidence: WBPaper00031872
            Curator_confirmed: WBPerson712
        Affected_by: Molecule: WBMol:00004019 Paper_evidence: WBPaper00031872
              Curator_confirmed: WBPerson712
      WBPhenotype:0000505 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: abnormal rays Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0000583 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: somewhat dumpy Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0000709 Paper_evidence: WBPaper00040002
        Curator_confirmed: WBPerson712
        Remark: mean pharynx length is significantly smaller than that of N2 Paper_evidence: WBPaper00040002
            Curator_confirmed: WBPerson712
        EQ_annotations: Anatomy_term: WBbt:0003681 PATO:0000460 Paper_evidence: WBPaper00040002
                Curator_confirmed: WBPerson712
          Life_stage: WBls:0000041 PATO:0000460 Paper_evidence: WBPaper00040002
                Curator_confirmed: WBPerson712
        Temperature_sensitive: Heat_sensitive: 25 Paper_evidence: WBPaper00040002
              Curator_confirmed: WBPerson712
      WBPhenotype:0001005 Paper_evidence: WBPaper00043908
        Curator_confirmed: WBPerson2987
      WBPhenotype:0001183 Paper_evidence: WBPaper00053184
        Curator_confirmed: WBPerson12433
      WBPhenotype:0001639 Paper_evidence: WBPaper00043908
        Curator_confirmed: WBPerson2987
      WBPhenotype:0002284 Paper_evidence: WBPaper00043908
        Curator_confirmed: WBPerson2987
      WBPhenotype:0002290 Paper_evidence: WBPaper00043908
        Curator_confirmed: WBPerson2987
      WBPhenotype:0002292 Paper_evidence: WBPaper00043908
        Curator_confirmed: WBPerson2987
      WBPhenotype:0002295 Paper_evidence: WBPaper00043908
        Curator_confirmed: WBPerson2987
      WBPhenotype:0002298 Paper_evidence: WBPaper00043908
        Curator_confirmed: WBPerson2987
      WBPhenotype:0002301 Paper_evidence: WBPaper00043908
        Curator_confirmed: WBPerson2987
      WBPhenotype:0002308 Paper_evidence: WBPaper00043908
        Curator_confirmed: WBPerson2987
      WBPhenotype:0002312 Paper_evidence: WBPaper00043908
        Curator_confirmed: WBPerson2987
      WBPhenotype:0002321 Paper_evidence: WBPaper00043908
        Curator_confirmed: WBPerson2987
      WBPhenotype:0002324 Paper_evidence: WBPaper00043908
        Curator_confirmed: WBPerson2987
      WBPhenotype:0002336 Paper_evidence: WBPaper00043908
        Curator_confirmed: WBPerson2987
      WBPhenotype:0002347 Paper_evidence: WBPaper00043908
        Curator_confirmed: WBPerson2987
      WBPhenotype:0004022 Paper_evidence: WBPaper00043908
        Curator_confirmed: WBPerson2987
      WBPhenotype:0004023 Paper_evidence: WBPaper00043908
        Curator_confirmed: WBPerson2987
    Phenotype_not_observed: WBPhenotype:0000164 Paper_evidence: WBPaper00032064
        Curator_confirmed: WBPerson712
        Remark: Animals were not significantly different from N2. Mean width was 11.5 0.1um (n=25) compared to 11.7 0.1 um for wild type. As determined by high-resolution, lensless, optofluidic microscopy method (OFM)-based on-chip microscopy. Paper_evidence: WBPaper00032064
            Curator_confirmed: WBPerson712
      WBPhenotype:0000901 Paper_evidence: WBPaper00040002
        Curator_confirmed: WBPerson712
        Remark: animals did not exhibit abnormal gland cell projections Paper_evidence: WBPaper00040002
            Curator_confirmed: WBPerson712
        EQ_annotations: Anatomy_term: WBbt:0005788 PATO:0000460 Paper_evidence: WBPaper00040002
                Curator_confirmed: WBPerson712
          Life_stage: WBls:0000041 PATO:0000460 Paper_evidence: WBPaper00040002
                Curator_confirmed: WBPerson712
        Temperature_sensitive: Heat_sensitive: 25 Paper_evidence: WBPaper00040002
              Curator_confirmed: WBPerson712
      WBPhenotype:0001426 Paper_evidence: WBPaper00004883
        Curator_confirmed: WBPerson712
        Phenotype_assay: Genotype: arIs37 Paper_evidence: WBPaper00004883
              Curator_confirmed: WBPerson712
  Reference (17)
  Remark: Variation stub/paper connection generated from the May 2021 NN VFP dataset.
    Created by WBPerson51134 from the NN_VFP_triage_pipeline
  Method: Allele