WormBase Tree Display for Variation: WBVar00088809
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WBVar00088809 | Name | Public_name | md176 | |||||
---|---|---|---|---|---|---|---|---|
Sequence_details | SeqStatus | Pending_curation | ||||||
Variation_type | Allele | |||||||
Origin | Species | Caenorhabditis elegans | ||||||
Strain (2) | ||||||||
Laboratory | RM | |||||||
Status | Live | |||||||
Affects | Gene | WBGene00001179 | ||||||
Interactor | WBInteraction000524571 | |||||||
WBInteraction000524572 | ||||||||
WBInteraction000524575 | ||||||||
Description | Phenotype (26) | |||||||
Phenotype_not_observed | WBPhenotype:0000017 | Paper_evidence | WBPaper00004721 | |||||
Curator_confirmed | WBPerson712 | |||||||
Remark | Fraction of animals moving after exposure to 0.5mM aldicarb is ~0.026 compared to N2 ~0.03. | Paper_evidence | WBPaper00004721 | |||||
Curator_confirmed | WBPerson712 | |||||||
Affected_by | Molecule | WBMol:00003650 | Paper_evidence | WBPaper00004721 | ||||
Curator_confirmed | WBPerson712 | |||||||
WBPhenotype:0000315 | Paper_evidence | WBPaper00037778 | ||||||
Curator_confirmed | WBPerson2987 | |||||||
Remark | egl-10(md176) mutants exhibited a wild type avoidance response to anterior body touch (Figure 1c) | Paper_evidence | WBPaper00037778 | |||||
Curator_confirmed | WBPerson2987 | |||||||
WBPhenotype:0001618 | Paper_evidence | WBPaper00004721 | ||||||
Curator_confirmed | WBPerson712 | |||||||
Remark | Animals exhibit an EC50 for halothane statistically insignificant from that of N2 as determined by a concentration-response curve based on animal dispersal indexes. | Paper_evidence | WBPaper00004721 | |||||
Curator_confirmed | WBPerson712 | |||||||
Variation_effect | Hypomorph_reduction_of_function | Paper_evidence | WBPaper00004721 | |||||
Curator_confirmed | WBPerson712 | |||||||
Affected_by | Molecule | WBMol:00001705 | Paper_evidence | WBPaper00004721 | ||||
Curator_confirmed | WBPerson712 | |||||||
WBPhenotype:0001619 | Paper_evidence | WBPaper00004721 | ||||||
Curator_confirmed | WBPerson712 | |||||||
Remark | Animals exhibit an EC50 for isoflurane statistically insignificant from that of N2 as determined by a concentration-response curve based on animal dispersal indexes. | Paper_evidence | WBPaper00004721 | |||||
Curator_confirmed | WBPerson712 | |||||||
Variation_effect | Hypomorph_reduction_of_function | Paper_evidence | WBPaper00004721 | |||||
Curator_confirmed | WBPerson712 | |||||||
Affected_by | Molecule | WBMol:00004563 | Paper_evidence | WBPaper00004721 | ||||
Curator_confirmed | WBPerson712 | |||||||
WBPhenotype:0002077 | Paper_evidence | WBPaper00041132 | ||||||
Curator_confirmed | WBPerson557 | |||||||
Remark | egl-10(md176) mutants are hypersensitive to the effects of exogenous dopamine on locomotion rate. | Paper_evidence | WBPaper00041132 | |||||
Curator_confirmed | WBPerson557 | |||||||
WBPhenotype:0002199 | Paper_evidence | WBPaper00037778 | ||||||
Curator_confirmed | WBPerson2987 | |||||||
Remark | The egl-10(md176) mutation did not affect the calcium transients in ASH neurons in response to high osmolarity (1M glycerol) (Figure 4a), 10 millimolar quinine (Figure 4b), or 1 millimolar copper (Figure 4c) | Paper_evidence | WBPaper00037778 | |||||
Curator_confirmed | WBPerson2987 | |||||||
Reference (8) | ||||||||
Method | Allele |