WormBase Tree Display for Variation: WBVar00091633

WBVar00091633 Evidence: Paper_evidence: WBPaper00031602
  Name: Public_name: ok335
    HGVSg: CHROMOSOME_I:g.1843615_1844684del
  Sequence_details: SMap: S_parent: Sequence: M01D7
    Flanking_sequences: taccggccacttcaggtagggaacaagaca aatcggcaaattgccgatttgtcgaatttg
    Mapping_target: M01D7
    Type_of_mutation: Deletion
    PCR_product: ok335_external
      ok335_internal
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00031371
    Laboratory: RB
    Person: WBPerson46
    KO_consortium_allele
    Status: Live
  Affects: Gene: WBGene00003750
    Transcript: M01D7.5.1 VEP_consequence: splice_acceptor_variant,coding_sequence_variant,3_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        Intron_number: 3/4
        Exon_number: 4-5/5
  Isolation: Mutagen: UV/TMP
  Genetics: Mapping_data: In_multi_point: 4536
  Description: Phenotype (20)
    Phenotype_not_observed: WBPhenotype:0000124 Paper_evidence: WBPaper00031602
        Curator_confirmed: WBPerson2021
        Remark: Lack of NLP-12 in C. elegans did not affect the in vivo amylase activity Paper_evidence: WBPaper00031602
            Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000038 PATO:0000460 Paper_evidence: WBPaper00031602
                Curator_confirmed: WBPerson2021
        Phenotype_assay: Treatment: Animals were subjected to 100 microM BODIPY FL conjugated DQ corn starch for 35 min in the presence of OP50 Paper_evidence: WBPaper00031602
              Curator_confirmed: WBPerson2021
      WBPhenotype:0000145 Paper_evidence: WBPaper00031602
        Curator_confirmed: WBPerson2021
      WBPhenotype:0000518 Paper_evidence: WBPaper00031602
        Curator_confirmed: WBPerson2021
      WBPhenotype:0000634 Paper_evidence: WBPaper00031602
        Curator_confirmed: WBPerson2021
        Remark: The lack of NLP-12 did not affect the pharyngeal pumping rate Paper_evidence: WBPaper00031602
            Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000038 PATO:0000460 Paper_evidence: WBPaper00031602
                Curator_confirmed: WBPerson2021
      WBPhenotype:0000643 Paper_evidence: WBPaper00031602
        Curator_confirmed: WBPerson2021
      WBPhenotype:0000650 Paper_evidence: WBPaper00031602
        Curator_confirmed: WBPerson2021
        Remark: Lack of NLP-12 did not affect the defecation rate Paper_evidence: WBPaper00031602
            Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000038 PATO:0000460 Paper_evidence: WBPaper00031602
                Curator_confirmed: WBPerson2021
  Reference: WBPaper00043908
    WBPaper00031602
    WBPaper00062141
  Remark: Sequenced by the C. elegans Gene Knockout Consortium Paper_evidence: WBPaper00041807
  Method: KO_consortium_allele