WormBase Tree Display for Variation: WBVar00094987
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| WBVar00094987 | Evidence | Paper_evidence | WBPaper00031426 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Name | Public_name | ox4 | |||||||
| Sequence_details | Mapping_target | Y44A6E | |||||||
| SeqStatus | Pending_curation | ||||||||
| Variation_type | Allele | ||||||||
| Origin | Species | Caenorhabditis elegans | |||||||
| Strain | WBStrain00006657 | ||||||||
| Laboratory | EG | ||||||||
| Status | Live | ||||||||
| Affects | Gene | WBGene00012857 | |||||||
| Isolation | Mutagen | EMS | Paper_evidence | WBPaper00031426 | |||||
| Description | Phenotype | WBPhenotype:0001641 | Paper_evidence | WBPaper00031426 | |||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | This defect cannot be bypassed by H+ ions. | Paper_evidence | WBPaper00031426 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Penetrance | Complete | Paper_evidence | WBPaper00031426 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Recessive | Paper_evidence | WBPaper00031426 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Phenotype_assay | Treatment | The presence or absence of each muscle contraction was scored for 11 defecation cycles in day 1 adults (n 6). NPE caged H+ ions were injected into animals and uncaged by flash stimulus of <360nm UV light for 1-3 sec. | Paper_evidence | WBPaper00031426 | |||||
| Curator_confirmed | WBPerson712 | ||||||||
| Phenotype_not_observed | WBPhenotype:0000643 | Paper_evidence | WBPaper00031426 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0000996 | Paper_evidence | WBPaper00031426 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Phenotype_assay | Treatment | The presence or absence of each muscle contraction was scored for 11 defecation cycles in day 1 adults (n 6). | Paper_evidence | WBPaper00031426 | |||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0001640 | Paper_evidence | WBPaper00031426 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | Observed extracellular acidic transients were similar to transients observed in pbo-4(-) animals with rescued PBO-4 function. | Paper_evidence | WBPaper00031426 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| EQ_annotations | Anatomy_term | WBbt:0005745 | PATO:0000460 | Paper_evidence | WBPaper00031426 | ||||
| Curator_confirmed | WBPerson712 | ||||||||
| Phenotype_assay | Treatment | Superecliptic pHlourin was expressed on the basolateral surface of the posterior intestine. Changes in pH were visualized by the quenching of fluorescence. | Paper_evidence | WBPaper00031426 | |||||
| Curator_confirmed | WBPerson712 | ||||||||
| Genotype | pbo-5(ox4); oxEx782[pHluorin::PBO-4] | Paper_evidence | WBPaper00031426 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Reference | WBPaper00031426 | ||||||||
| Method | Allele |
