WormBase Tree Display for Variation: WBVar00142936
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| WBVar00142936 | Evidence | Paper_evidence | WBPaper00005582 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Name | Public_name | e53 | |||||||
| Other_name | B0273.4f.1:c.62G>A | ||||||||
| B0273.4d.1:c.524G>A | |||||||||
| B0273.4b.1:c.848G>A | |||||||||
| CE37693:p.Trp283Ter | |||||||||
| CE49300:p.Trp21Ter | |||||||||
| CE49241:p.Trp175Ter | |||||||||
| B0273.4c.1:c.932G>A | |||||||||
| B0273.4e.1:c.347G>A | |||||||||
| B0273.4d.2:c.524G>A | |||||||||
| B0273.4a.1:c.848G>A | |||||||||
| CE16791:p.Trp311Ter | |||||||||
| CE49455:p.Trp116Ter | |||||||||
| CE16790:p.Trp283Ter | |||||||||
| HGVSg | CHROMOSOME_IV:g.5499260C>T | ||||||||
| Sequence_details | SMap | S_parent | Sequence | B0273 | |||||
| Flanking_sequences | ttgatggaggatggagttcatggagtgatt | gagtgcttgctcttcgagttgtcatcggta | |||||||
| Mapping_target | B0273 | ||||||||
| Type_of_mutation | Substitution | g | a | ||||||
| SeqStatus | Sequenced | ||||||||
| Variation_type | Allele | ||||||||
| Origin | Species | Caenorhabditis elegans | |||||||
| Strain | WBStrain00004233 | ||||||||
| WBStrain00004501 | |||||||||
| WBStrain00004562 | |||||||||
| WBStrain00004583 | |||||||||
| WBStrain00004944 | |||||||||
| WBStrain00004946 | |||||||||
| WBStrain00004964 | |||||||||
| WBStrain00004970 | |||||||||
| WBStrain00004993 | |||||||||
| WBStrain00005001 | |||||||||
| WBStrain00006207 | |||||||||
| WBStrain00006208 | |||||||||
| WBStrain00006288 | |||||||||
| WBStrain00006296 | |||||||||
| WBStrain00006297 | |||||||||
| WBStrain00006298 | |||||||||
| WBStrain00006299 | |||||||||
| WBStrain00006300 | |||||||||
| WBStrain00006303 | |||||||||
| WBStrain00006304 | |||||||||
| WBStrain00006305 | |||||||||
| WBStrain00006306 | |||||||||
| WBStrain00006307 | |||||||||
| WBStrain00006308 | |||||||||
| WBStrain00006309 | |||||||||
| WBStrain00006310 | |||||||||
| WBStrain00006317 | |||||||||
| WBStrain00007255 | |||||||||
| WBStrain00022026 | |||||||||
| WBStrain00022039 | |||||||||
| WBStrain00022044 | |||||||||
| WBStrain00022515 | |||||||||
| WBStrain00022609 | |||||||||
| WBStrain00026734 | |||||||||
| WBStrain00026769 | |||||||||
| WBStrain00027012 | |||||||||
| WBStrain00027101 | |||||||||
| WBStrain00027161 | |||||||||
| WBStrain00027195 | |||||||||
| WBStrain00027196 | |||||||||
| WBStrain00027197 | |||||||||
| WBStrain00033485 | |||||||||
| WBStrain00033529 | |||||||||
| WBStrain00034349 | |||||||||
| WBStrain00034706 | |||||||||
| WBStrain00035709 | |||||||||
| WBStrain00040435 | |||||||||
| WBStrain00040573 | |||||||||
| WBStrain00047007 | |||||||||
| Laboratory | CB | ||||||||
| Status | Live | ||||||||
| Affects | Gene | WBGene00006745 | |||||||
| Transcript | B0273.4f.1 | VEP_consequence | stop_gained | ||||||
| VEP_impact | HIGH | ||||||||
| HGVSc | B0273.4f.1:c.62G>A | ||||||||
| HGVSp | CE49300:p.Trp21Ter | ||||||||
| cDNA_position | 62 | ||||||||
| CDS_position | 62 | ||||||||
| Protein_position | 21 | ||||||||
| Exon_number | 1/4 | ||||||||
| Codon_change | tGg/tAg | ||||||||
| Amino_acid_change | W/* | ||||||||
| B0273.4e.1 | VEP_consequence | stop_gained | |||||||
| VEP_impact | HIGH | ||||||||
| HGVSc | B0273.4e.1:c.347G>A | ||||||||
| HGVSp | CE49455:p.Trp116Ter | ||||||||
| cDNA_position | 347 | ||||||||
| CDS_position | 347 | ||||||||
| Protein_position | 116 | ||||||||
| Exon_number | 2/5 | ||||||||
| Codon_change | tGg/tAg | ||||||||
| Amino_acid_change | W/* | ||||||||
| B0273.4c.1 | VEP_consequence | stop_gained | |||||||
| VEP_impact | HIGH | ||||||||
| HGVSc | B0273.4c.1:c.932G>A | ||||||||
| HGVSp | CE16791:p.Trp311Ter | ||||||||
| cDNA_position | 932 | ||||||||
| CDS_position | 932 | ||||||||
| Protein_position | 311 | ||||||||
| Exon_number | 6/10 | ||||||||
| Codon_change | tGg/tAg | ||||||||
| Amino_acid_change | W/* | ||||||||
| B0273.4a.1 | VEP_consequence | stop_gained | |||||||
| VEP_impact | HIGH | ||||||||
| HGVSc | B0273.4a.1:c.848G>A | ||||||||
| HGVSp | CE16790:p.Trp283Ter | ||||||||
| cDNA_position | 850 | ||||||||
| CDS_position | 848 | ||||||||
| Protein_position | 283 | ||||||||
| Exon_number | 6/10 | ||||||||
| Codon_change | tGg/tAg | ||||||||
| Amino_acid_change | W/* | ||||||||
| B0273.4d.2 | VEP_consequence | stop_gained | |||||||
| VEP_impact | HIGH | ||||||||
| HGVSc | B0273.4d.2:c.524G>A | ||||||||
| HGVSp | CE49241:p.Trp175Ter | ||||||||
| cDNA_position | 528 | ||||||||
| CDS_position | 524 | ||||||||
| Protein_position | 175 | ||||||||
| Exon_number | 4/8 | ||||||||
| Codon_change | tGg/tAg | ||||||||
| Amino_acid_change | W/* | ||||||||
| B0273.4b.1 | VEP_consequence | stop_gained | |||||||
| VEP_impact | HIGH | ||||||||
| HGVSc | B0273.4b.1:c.848G>A | ||||||||
| HGVSp | CE37693:p.Trp283Ter | ||||||||
| cDNA_position | 848 | ||||||||
| CDS_position | 848 | ||||||||
| Protein_position | 283 | ||||||||
| Exon_number | 5/6 | ||||||||
| Codon_change | tGg/tAg | ||||||||
| Amino_acid_change | W/* | ||||||||
| B0273.4d.1 | VEP_consequence | stop_gained | |||||||
| VEP_impact | HIGH | ||||||||
| HGVSc | B0273.4d.1:c.524G>A | ||||||||
| HGVSp | CE49241:p.Trp175Ter | ||||||||
| cDNA_position | 727 | ||||||||
| CDS_position | 524 | ||||||||
| Protein_position | 175 | ||||||||
| Exon_number | 5/9 | ||||||||
| Codon_change | tGg/tAg | ||||||||
| Amino_acid_change | W/* | ||||||||
| Interactor | WBInteraction000500380 | ||||||||
| WBInteraction000500381 | |||||||||
| WBInteraction000500385 | |||||||||
| WBInteraction000500931 | |||||||||
| WBInteraction000503768 | |||||||||
| WBInteraction000503769 | |||||||||
| WBInteraction000517893 | |||||||||
| WBInteraction000535488 | |||||||||
| WBInteraction000538519 | |||||||||
| WBInteraction000538520 | |||||||||
| WBInteraction000538521 | |||||||||
| WBInteraction000538522 | |||||||||
| WBInteraction000538523 | |||||||||
| WBInteraction000538524 | |||||||||
| WBInteraction000538525 | |||||||||
| WBInteraction000538530 | |||||||||
| WBInteraction000538543 | |||||||||
| WBInteraction000538544 | |||||||||
| WBInteraction000538545 | |||||||||
| WBInteraction000538546 | |||||||||
| WBInteraction000538547 | |||||||||
| WBInteraction000538552 | |||||||||
| WBInteraction000538553 | |||||||||
| WBInteraction000538554 | |||||||||
| WBInteraction000538555 | |||||||||
| WBInteraction000538556 | |||||||||
| Genetics | Interpolated_map_position | IV | 1.757 | ||||||
| Mapping_data | In_2_point | 93 | |||||||
| 104 | |||||||||
| 118 | |||||||||
| 820 | |||||||||
| 1649 | |||||||||
| 3270 | |||||||||
| 3378 | |||||||||
| 3729 | |||||||||
| 6088 | |||||||||
| 7050 | |||||||||
| In_multi_point | 105 | ||||||||
| 106 | |||||||||
| 371 | |||||||||
| 382 | |||||||||
| 768 | |||||||||
| 770 | |||||||||
| 772 | |||||||||
| 774 | |||||||||
| 776 | |||||||||
| 777 | |||||||||
| 778 | |||||||||
| 798 | |||||||||
| 897 | |||||||||
| 898 | |||||||||
| 905 | |||||||||
| 918 | |||||||||
| 919 | |||||||||
| 921 | |||||||||
| 922 | |||||||||
| 1114 | |||||||||
| 1120 | |||||||||
| 1122 | |||||||||
| 1260 | |||||||||
| 1267 | |||||||||
| 1270 | |||||||||
| 1287 | |||||||||
| 1365 | |||||||||
| 1511 | |||||||||
| 1512 | |||||||||
| 1522 | |||||||||
| 1792 | |||||||||
| 1793 | |||||||||
| 2003 | |||||||||
| 2006 | |||||||||
| 2020 | |||||||||
| 2023 | |||||||||
| 2024 | |||||||||
| 2237 | |||||||||
| 2238 | |||||||||
| 2827 | |||||||||
| 3018 | |||||||||
| 3060 | |||||||||
| 3061 | |||||||||
| 3062 | |||||||||
| 3135 | |||||||||
| 3251 | |||||||||
| 5460 | |||||||||
| In_pos_neg_data | 3700 | ||||||||
| Description | Phenotype | WBPhenotype:0000004 | Person_evidence | WBPerson261 | |||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0000181 | Paper_evidence | WBPaper00031671 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Remark | Mutation in the unc-5 gene results in premature termination of both the dorsal and sub-ventral process of the NSM neurons: 26% of the dorsal processes are short and 13% are absent | Paper_evidence | WBPaper00031671 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Variation_effect | Null | Paper_evidence | WBPaper00031671 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Anatomy_term | WBbt:0003666 | PATO:0000460 | Paper_evidence | WBPaper00031671 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Phenotype_assay | Genotype | zdIs13 [ tph-1p::GFP] | Paper_evidence | WBPaper00031671 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0000188 | Person_evidence | WBPerson261 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | abnormal gonad arms | Person_evidence | WBPerson261 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0000195 | Paper_evidence | WBPaper00005809 | |||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| Remark | Table 1 | Paper_evidence | WBPaper00005809 | ||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| Penetrance | Incomplete | Paper_evidence | WBPaper00005809 | ||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| Variation_effect | Null | Paper_evidence | WBPaper00005809 | ||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| EQ_annotations | Anatomy_term | WBbt:0006865 | PATO:0000460 | Paper_evidence | WBPaper00005809 | ||||
| Curator_confirmed | WBPerson2987 | ||||||||
| GO_term | GO:0016477 | PATO:0000460 | Paper_evidence | WBPaper00005809 | |||||
| Curator_confirmed | WBPerson2987 | ||||||||
| WBPhenotype:0000384 | Paper_evidence | WBPaper00032163 | |||||||
| WBPaper00040147 | |||||||||
| WBPaper00031828 | |||||||||
| WBPaper00040041 | |||||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | Half of animals exhibited DA9 axon guidance defects. Axon guidance defects in VD and DD neurons were not enhnaced by expression of UNC-5 at the L4 larval stage. | Paper_evidence | WBPaper00032163 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Mutants displayed a nearly complete failure of dorsally directed VD axons to reach the dorsal cord. | Paper_evidence | WBPaper00040147 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Animals exhibit dorsal guidance defects. | Paper_evidence | WBPaper00031828 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| DD and VD axon guidance defects were not suppressed by acetylcholine. | Paper_evidence | WBPaper00040041 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Affected_by | Molecule | WBMol:00004765 | Paper_evidence | WBPaper00040041 | |||||
| Curator_confirmed | WBPerson712 | ||||||||
| EQ_annotations | Anatomy_term | WBbt:0005303 | PATO:0000460 | Paper_evidence | WBPaper00032163 | ||||
| WBPaper00040147 | |||||||||
| WBPaper00040041 | |||||||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBbt:0005270 | PATO:0000460 | Paper_evidence | WBPaper00032163 | ||||||
| WBPaper00040041 | |||||||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBbt:0005274 | PATO:0000460 | Paper_evidence | WBPaper00031828 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBbt:0005278 | PATO:0000460 | Paper_evidence | WBPaper00031828 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Phenotype_assay | Treatment | 25 | Paper_evidence | WBPaper00032163 | |||||
| Curator_confirmed | WBPerson712 | ||||||||
| Genotype | unc-5::intron::unc-5 | Paper_evidence | WBPaper00032163 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0000516 | Person_evidence | WBPerson261 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | distribution of cell bodies in ventral cord is disorganized | Person_evidence | WBPerson261 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0000539 | Person_evidence | WBPerson261 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | dorsal nerve cord absent or almost absent | Person_evidence | WBPerson261 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| EQ_annotations | Anatomy_term | WBbt:0006750 | PATO:0000460 | Person_evidence | WBPerson261 | ||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0000540 | Person_evidence | WBPerson261 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | muscle arms misdirected | Person_evidence | WBPerson261 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0000541 | Person_evidence | WBPerson261 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | cord commissures fail to reach targets | Person_evidence | WBPerson261 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0000565 | Person_evidence | WBPerson261 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | severe coiler, L1 also severe coiler | Person_evidence | WBPerson261 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Ease_of_scoring | ES3_Easy_to_score | Person_evidence | WBPerson261 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0000633 | Paper_evidence | WBPaper00040147 | |||||||
| WBPaper00045955 | |||||||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPerson557 | |||||||||
| Remark | Branch defects scored in PLM neuron. | Paper_evidence | WBPaper00045955 | ||||||
| Curator_confirmed | WBPerson557 | ||||||||
| Penetrance | Low | Paper_evidence | WBPaper00045955 | ||||||
| Curator_confirmed | WBPerson557 | ||||||||
| EQ_annotations | Anatomy_term | WBbt:0005303 | PATO:0000460 | Paper_evidence | WBPaper00040147 | ||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBbt:0005270 | PATO:0000460 | Paper_evidence | WBPaper00040147 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0000643 | Paper_evidence | WBPaper00000031 | |||||||
| WBPaper00001019 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson712 | |||||||||
| Variation_effect | Null | Paper_evidence | WBPaper00000031 | ||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPhenotype:0000672 | Paper_evidence | WBPaper00032163 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | The average number of GFP::RAB-3 puncta in the DA9 axon was reduced. | Paper_evidence | WBPaper00032163 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| EQ_annotations | Anatomy_term | WBbt:0004857 | PATO:0000460 | Paper_evidence | WBPaper00032163 | ||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0000802 | Person_evidence | WBPerson261 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | dorsal hypodermal cells abnormal | Person_evidence | WBPerson261 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| EQ_annotations | Anatomy_term | WBbt:0007846 | PATO:0000460 | Person_evidence | WBPerson261 | ||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0000847 | Paper_evidence | WBPaper00032163 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | Presynaptic components, such as RAB-3, SNB-1/synaptobrevin and SNG-1/synaptogyrin, the L-type voltage gated calcium channel b-subunit CCB-1, and the active zone protein SYD-2/a-liprin were mislocalized to the dendrite. Mislocalization defects in L1 and adult animals were rescued by a mig-5::unc-5 transgene and not unc-25::unc-5 or unc-129::unc-5 transgenes. | Paper_evidence | WBPaper00032163 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| EQ_annotations | Anatomy_term | WBbt:0004857 | PATO:0000460 | Paper_evidence | WBPaper00032163 | ||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0000880 | Paper_evidence | WBPaper00056066 | |||||||
| Curator_confirmed | WBPerson18979 | ||||||||
| Remark | ALA axon mispositioned | Paper_evidence | WBPaper00056066 | ||||||
| Curator_confirmed | WBPerson18979 | ||||||||
| EQ_annotations | Anatomy_term | WBbt:0003955 | PATO:0000460 | Paper_evidence | WBPaper00056066 | ||||
| Curator_confirmed | WBPerson18979 | ||||||||
| GO_term | GO:0030424 | PATO:0000628 | Paper_evidence | WBPaper00056066 | |||||
| Curator_confirmed | WBPerson18979 | ||||||||
| WBPhenotype:0000882 | Paper_evidence | WBPaper00032163 | |||||||
| WBPaper00056066 | |||||||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPerson18979 | |||||||||
| Remark | The localization of four dendritically localized proteins (CAM-1/ROR16, UNC-9/innexin, F35D2.3/fibrillin and DYS-1/dystrophin16) were unaffected. | Paper_evidence | WBPaper00032163 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| PVD 1° dendrite branch mispositioned | Paper_evidence | WBPaper00056066 | |||||||
| Curator_confirmed | WBPerson18979 | ||||||||
| EQ_annotations | Anatomy_term | WBbt:0004857 | PATO:0000460 | Paper_evidence | WBPaper00032163 | ||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBbt:0006831 | PATO:0000460 | Paper_evidence | WBPaper00056066 | ||||||
| Curator_confirmed | WBPerson18979 | ||||||||
| GO_term | GO:0044307 | PATO:0000628 | Paper_evidence | WBPaper00056066 | |||||
| Curator_confirmed | WBPerson18979 | ||||||||
| WBPhenotype:0001224 | Paper_evidence | WBPaper00038105 | |||||||
| WBPaper00003665 | |||||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | DA and DB axons are misrouted and fail to fully migrate to the dorsal cord. In some animals, axons fail to exit the ventral cord. | Paper_evidence | WBPaper00038105 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| 99% of animals showed wild-type ASI amphid neuron outgrowth. Mutants also showed lateral axon outgrowth (1%). | Paper_evidence | WBPaper00003665 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Penetrance | Low | 1% | Paper_evidence | WBPaper00003665 | |||||
| Curator_confirmed | WBPerson712 | ||||||||
| EQ_annotations | Anatomy_term | WBbt:0005666 | PATO:0000460 | Paper_evidence | WBPaper00003665 | ||||
| Curator_confirmed | WBPerson712 | ||||||||
| Phenotype_assay | Genotype | kyIs128[str-3::GFP] | Paper_evidence | WBPaper00003665 | |||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0001801 | Paper_evidence | WBPaper00032163 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | Presynaptic components such as RAB-3, calcium channel subunits and other active zone proteins are not excluded from DA9 dendrites as they are in control animals. | Paper_evidence | WBPaper00032163 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0001931 | Paper_evidence | WBPaper00032907 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | Animals have 4-6 muscle arms per side that project into the lateral space as they extended towards misguided commissural motor axons. | Paper_evidence | WBPaper00032907 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Phenotype_not_observed | WBPhenotype:0000030 | Person_evidence | WBPerson261 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | grows well | Person_evidence | WBPerson261 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0000384 | Paper_evidence | WBPaper00036484 | |||||||
| WBPaper00040147 | |||||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | The primary axon of ADL grows into the nerve ring ventrally rather than laterally. This phenotype occurs at a lower frequency than the axon branching phenotype. AVM axons fail to grow ventrally. HSN motor neurons fail to polarize properly. | Paper_evidence | WBPaper00036484 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Animals do not exhibit any defects in ventrally-directed HSN axon guidance. | Paper_evidence | WBPaper00040147 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Penetrance | Incomplete | Paper_evidence | WBPaper00036484 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| EQ_annotations | Anatomy_term | WBbt:0005661 | PATO:0000460 | Paper_evidence | WBPaper00036484 | ||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBbt:0006830 | PATO:0000460 | Paper_evidence | WBPaper00040147 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0000469 | Paper_evidence | WBPaper00004437 | |||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| Remark | "We found that unc-5 mutants also had almost normal Q cell migrations (Fig. 2); thus UNC-5 does not appear to be a part of the UNC-40-dependent Q guidance system." | Paper_evidence | WBPaper00004437 | ||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| EQ_annotations | Anatomy_term | WBbt:0004056 | PATO:0000460 | Paper_evidence | WBPaper00004437 | ||||
| Curator_confirmed | WBPerson2987 | ||||||||
| WBbt:0004054 | PATO:0000460 | Paper_evidence | WBPaper00004437 | ||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| GO_term | GO:0016477 | PATO:0000460 | Paper_evidence | WBPaper00004437 | |||||
| Curator_confirmed | WBPerson2987 | ||||||||
| WBPhenotype:0000631 | Paper_evidence | WBPaper00035198 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | Animals do not exhibit anterior convulsions when treated with pentylenetetrazole(PTZ). | Paper_evidence | WBPaper00035198 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Variation_effect | Null | Paper_evidence | WBPaper00035198 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Affected_by | Molecule | WBMol:00004251 | Paper_evidence | WBPaper00035198 | |||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0000633 | Paper_evidence | WBPaper00036484 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | ADL projects normal dorsal and ventral branches. | Paper_evidence | WBPaper00036484 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Penetrance | Incomplete | Paper_evidence | WBPaper00036484 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| EQ_annotations | Anatomy_term | WBbt:0005661 | PATO:0000460 | Paper_evidence | WBPaper00036484 | ||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0001645 | Paper_evidence | WBPaper00040284 | |||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| Remark | Table 1 | Paper_evidence | WBPaper00040284 | ||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| WBPhenotype:0001652 | Paper_evidence | WBPaper00032446 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0001930 | Paper_evidence | WBPaper00032907 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | Ventral muscle arm extension in animals was indistinguishable from that of wild-type controls. | Paper_evidence | WBPaper00032907 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Reference | WBPaper00038105 | ||||||||
| WBPaper00040041 | |||||||||
| WBPaper00040284 | |||||||||
| WBPaper00040147 | |||||||||
| WBPaper00029020 | |||||||||
| WBPaper00031671 | |||||||||
| WBPaper00015171 | |||||||||
| WBPaper00017709 | |||||||||
| WBPaper00032446 | |||||||||
| WBPaper00000031 | |||||||||
| WBPaper00018249 | |||||||||
| WBPaper00035198 | |||||||||
| WBPaper00001019 | |||||||||
| WBPaper00005809 | |||||||||
| WBPaper00016091 | |||||||||
| WBPaper00015529 | |||||||||
| WBPaper00015530 | |||||||||
| WBPaper00004437 | |||||||||
| WBPaper00032907 | |||||||||
| WBPaper00003665 | |||||||||
| WBPaper00016497 | |||||||||
| WBPaper00022702 | |||||||||
| WBPaper00016299 | |||||||||
| WBPaper00016552 | |||||||||
| WBPaper00016473 | |||||||||
| WBPaper00031828 | |||||||||
| WBPaper00036484 | |||||||||
| WBPaper00016407 | |||||||||
| WBPaper00013812 | |||||||||
| WBPaper00032163 | |||||||||
| WBPaper00013809 | |||||||||
| WBPaper00005582 | |||||||||
| WBPaper00026419 | |||||||||
| WBPaper00019269 | |||||||||
| WBPaper00015081 | |||||||||
| WBPaper00011608 | |||||||||
| WBPaper00045955 | |||||||||
| WBPaper00056066 | |||||||||
| Method | Substitution_allele |
