WormBase Tree Display for Variation: WBVar00251725
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WBVar00251725 | Name | Public_name | tm2912 | |||||
---|---|---|---|---|---|---|---|---|
Other_name | F02E8.3.1:c.268-38_423del | |||||||
HGVSg | CHROMOSOME_X:g.4458921_4459114del | |||||||
Sequence_details (7) | ||||||||
Variation_type | Allele | |||||||
Origin | Species | Caenorhabditis elegans | ||||||
Laboratory | FX | |||||||
Author | Mitani S | |||||||
DB_info | Database | National_Bioresource_Project | seq | 2912 | ||||
NBP_allele | ||||||||
Status | Live | |||||||
Affects | Gene | WBGene00000157 | ||||||
Transcript | F02E8.3.1 | VEP_consequence | splice_acceptor_variant,coding_sequence_variant,intron_variant | |||||
VEP_impact | HIGH | |||||||
HGVSc | F02E8.3.1:c.268-38_423del | |||||||
cDNA_position | ?-423 | |||||||
CDS_position | ?-423 | |||||||
Protein_position | ?-141 | |||||||
Intron_number | 2/3 | |||||||
Exon_number | 3/4 | |||||||
Interactor | WBInteraction000525183 | |||||||
Isolation | Mutagen | TMP/UV | ||||||
Genetics | Map | X | ||||||
Description | Phenotype (3) | |||||||
Phenotype_not_observed | WBPhenotype:0000643 | Paper_evidence | WBPaper00032011 | |||||
Curator_confirmed | WBPerson712 | |||||||
Remark | Animals displayed defects in a temperature-dependent manner. Motor activities of animals harboring synWT, synA53T or synA30P transgenes were severely impaired, while animals not containing any transgene or containing a control transgene were almost normal. | Paper_evidence | WBPaper00032011 | |||||
Curator_confirmed | WBPerson712 | |||||||
Temperature_sensitive | Heat_sensitive | 20 | Paper_evidence | WBPaper00032011 | ||||
Curator_confirmed | WBPerson712 | |||||||
Phenotype_assay | Temperature | 15,20 | Paper_evidence | WBPaper00032011 | ||||
Curator_confirmed | WBPerson712 | |||||||
Genotype | tmIs429, tmIs430, tmIs431 or tmIs432 | Paper_evidence | WBPaper00032011 | |||||
Curator_confirmed | WBPerson712 | |||||||
Reference | WBPaper00032011 | |||||||
Remark | 11246/11247-11440/11441 (194 bp deletion) | |||||||
This knockout was generated by the National Bioresource Project, Tokyo, Japan, which is part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. | Paper_evidence | WBPaper00041807 | ||||||
Method | NBP_knockout_allele |