WormBase Tree Display for Variation: WBVar00251773

WBVar00251773 Name: Public_name: tm2979
    Other_name: CE36619:p.Tyr52_Asn106del
      Y39B6A.2a.1:c.154_318del
    HGVSg: CHROMOSOME_V:g.19190766_19190930del
  Sequence_details: SMap: S_parent: Sequence: Y39B6A
    Flanking_sequences: gatcaagtgtacgacgtggccgccgacctc atggctctggggcggtttaaaaaggcgttg
    Mapping_target: Y39B6A
    Source_location: 7 CHROMOSOME_V 19190765 19190931 Inferred_automatically: National_Bioresource_Project
    Type_of_mutation: Deletion
    PCR_product: tm2979_external
      tm2979_internal
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Laboratory: FX
    Author: Mitani S
    DB_info: Database: National_Bioresource_Project seq 2979
    NBP_allele
    Status: Live
  Affects: Gene: WBGene00012665
    Transcript: Y39B6A.2a.1 VEP_consequence: inframe_deletion
        VEP_impact: MODERATE
        HGVSc: Y39B6A.2a.1:c.154_318del
        HGVSp: CE36619:p.Tyr52_Asn106del
        cDNA_position: 162-326
        CDS_position: 154-318
        Protein_position: 52-106
        Exon_number: 3/10
        Codon_change: TACTCTGTCGCAATTGAGATTCATCCGACGGCGGTTCTTTACGGAAACCGTGCACAGGCCTATCTGAAGAAAGAGCTCTACGGAAGTGCTCTTGAGGATGCGGACAACGCGATTGCAATTGATCCGTCATATGTGAAGGGATTCTATAGAAGAGCTACCGCCAAT/-
        Amino_acid_change: YSVAIEIHPTAVLYGNRAQAYLKKELYGSALEDADNAIAIDPSYVKGFYRRATAN/-
    Interactor: WBInteraction000500816
      WBInteraction000500817
  Isolation: Mutagen: TMP/UV
  Genetics: Map: V
  Description: Phenotype_not_observed: WBPhenotype:0000050 Paper_evidence: WBPaper00040142
        Curator_confirmed: WBPerson712
        Remark: Animals are healthy at all temperatures. Paper_evidence: WBPaper00040142
            Curator_confirmed: WBPerson712
        Phenotype_assay: Temperature: 24 Paper_evidence: WBPaper00040142
              Curator_confirmed: WBPerson712
      WBPhenotype:0000062 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Classified as 'homozygous viable' by the National Bioresource Project of Japan. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
      WBPhenotype:0000112 Paper_evidence: WBPaper00040142
        Curator_confirmed: WBPerson712
        Remark: PPH-5 protein could be detected. Paper_evidence: WBPaper00040142
            Curator_confirmed: WBPerson712
        Phenotype_assay: Temperature: 24 Paper_evidence: WBPaper00040142
              Curator_confirmed: WBPerson712
      WBPhenotype:0000688 Paper_evidence: WBPaper00040142
        Curator_confirmed: WBPerson712
        Remark: Animals are fertile at all temperatures. Paper_evidence: WBPaper00040142
            Curator_confirmed: WBPerson712
        Phenotype_assay: Temperature: 24 Paper_evidence: WBPaper00040142
              Curator_confirmed: WBPerson712
  Reference: WBPaper00040142
  Remark: 232709/232710-232874/232875 (165 bp deletion)
    This knockout was generated by the National Bioresource Project, Tokyo, Japan, which is part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence: WBPaper00041807
  Method: NBP_knockout_allele