WormBase Tree Display for Variation: WBVar02147969

WBVar02147969 Name: Public_name: tm10161
    Other_name: F25C8.3e.1:c.7763_7926delinsGCCAAACGTCAAAGTTTTCGAAAAAGAGCA
      CE47217:p.Leu2623CysfsTer20
      CE47428:p.Leu2588CysfsTer20
      F25C8.3a.1:c.7958_8121delinsGCCAAACGTCAAAGTTTTCGAAAAAGAGCA
      CE41563:p.Leu2653CysfsTer20
      CE43592:p.Leu2691CysfsTer20
      F25C8.3d.1:c.8072_8235delinsGCCAAACGTCAAAGTTTTCGAAAAAGAGCA
      F25C8.3c.1:c.7868_8031delinsGCCAAACGTCAAAGTTTTCGAAAAAGAGCA
      F25C8.3b.1:c.7895_8058delinsGCCAAACGTCAAAGTTTTCGAAAAAGAGCA
      CE47117:p.Leu2632CysfsTer20
    HGVSg: CHROMOSOME_V:g.20896274_20896437delinsGCCAAACGTCAAAGTTTTCGAAAAAGAGCA
  Sequence_details: SMap: S_parent: Sequence: F25C8
    Flanking_sequences: tggccttgttgaaagttgctccctatgatt atttggatagcactttcatcgtggattaat
    Mapping_target: F25C8
    Source_location: 7 CHROMOSOME_V 20896273 20896438 Inferred_automatically: National_Bioresource_Project
    Type_of_mutation: Insertion: GCCAAACGTCAAAGTTTTCGAAAAAGAGCA
      Deletion
    PCR_product: tm10161_external
      tm10161_internal
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Laboratory: FX
    Author: Mitani S
    DB_info: Database: National_Bioresource_Project seq 10161
    NBP_allele
    Status: Live
  Affects: Gene: WBGene00006812
    Transcript: F25C8.3d.1 VEP_consequence: frameshift_variant
        VEP_impact: HIGH
        HGVSc: F25C8.3d.1:c.8072_8235delinsGCCAAACGTCAAAGTTTTCGAAAAAGAGCA
        HGVSp: CE43592:p.Leu2691CysfsTer20
        cDNA_position: 8072-8235
        CDS_position: 8072-8235
        Protein_position: 2691-2745
        Exon_number: 32/37
        Codon_change: tTATCAACTACAACGTGTCACGGTCTTCAGAAATATTTCCAGATAATACTACCAGTTACTGATTGGAGTATAGAGTCTAACAGGAGTGCTCTCAATATTATTCTACGACGATTAGACAAAACACTATCCAAGATTGCCAAACGTCAAAGTTTTCGAAAAAGAGCT/tGCCAAACGTCAAAGTTTTCGAAAAAGAGCA
        Amino_acid_change: LSTTTCHGLQKYFQIILPVTDWSIESNRSALNIILRRLDKTLSKIAKRQSFRKRA/CQTSKFSKKSX
      F25C8.3b.1 VEP_consequence: frameshift_variant
        VEP_impact: HIGH
        HGVSc: F25C8.3b.1:c.7895_8058delinsGCCAAACGTCAAAGTTTTCGAAAAAGAGCA
        HGVSp: CE47117:p.Leu2632CysfsTer20
        cDNA_position: 8148-8311
        CDS_position: 7895-8058
        Protein_position: 2632-2686
        Exon_number: 30/36
        Codon_change: tTATCAACTACAACGTGTCACGGTCTTCAGAAATATTTCCAGATAATACTACCAGTTACTGATTGGAGTATAGAGTCTAACAGGAGTGCTCTCAATATTATTCTACGACGATTAGACAAAACACTATCCAAGATTGCCAAACGTCAAAGTTTTCGAAAAAGAGCT/tGCCAAACGTCAAAGTTTTCGAAAAAGAGCA
        Amino_acid_change: LSTTTCHGLQKYFQIILPVTDWSIESNRSALNIILRRLDKTLSKIAKRQSFRKRA/CQTSKFSKKSX
      F25C8.3e.1 VEP_consequence: frameshift_variant
        VEP_impact: HIGH
        HGVSc: F25C8.3e.1:c.7763_7926delinsGCCAAACGTCAAAGTTTTCGAAAAAGAGCA
        HGVSp: CE47428:p.Leu2588CysfsTer20
        cDNA_position: 7763-7926
        CDS_position: 7763-7926
        Protein_position: 2588-2642
        Exon_number: 28/34
        Codon_change: tTATCAACTACAACGTGTCACGGTCTTCAGAAATATTTCCAGATAATACTACCAGTTACTGATTGGAGTATAGAGTCTAACAGGAGTGCTCTCAATATTATTCTACGACGATTAGACAAAACACTATCCAAGATTGCCAAACGTCAAAGTTTTCGAAAAAGAGCT/tGCCAAACGTCAAAGTTTTCGAAAAAGAGCA
        Amino_acid_change: LSTTTCHGLQKYFQIILPVTDWSIESNRSALNIILRRLDKTLSKIAKRQSFRKRA/CQTSKFSKKSX
      F25C8.3c.1 VEP_consequence: frameshift_variant
        VEP_impact: HIGH
        HGVSc: F25C8.3c.1:c.7868_8031delinsGCCAAACGTCAAAGTTTTCGAAAAAGAGCA
        HGVSp: CE47217:p.Leu2623CysfsTer20
        cDNA_position: 7868-8031
        CDS_position: 7868-8031
        Protein_position: 2623-2677
        Exon_number: 30/35
        Codon_change: tTATCAACTACAACGTGTCACGGTCTTCAGAAATATTTCCAGATAATACTACCAGTTACTGATTGGAGTATAGAGTCTAACAGGAGTGCTCTCAATATTATTCTACGACGATTAGACAAAACACTATCCAAGATTGCCAAACGTCAAAGTTTTCGAAAAAGAGCT/tGCCAAACGTCAAAGTTTTCGAAAAAGAGCA
        Amino_acid_change: LSTTTCHGLQKYFQIILPVTDWSIESNRSALNIILRRLDKTLSKIAKRQSFRKRA/CQTSKFSKKSX
      F25C8.3a.1 VEP_consequence: frameshift_variant
        VEP_impact: HIGH
        HGVSc: F25C8.3a.1:c.7958_8121delinsGCCAAACGTCAAAGTTTTCGAAAAAGAGCA
        HGVSp: CE41563:p.Leu2653CysfsTer20
        cDNA_position: 7958-8121
        CDS_position: 7958-8121
        Protein_position: 2653-2707
        Exon_number: 31/37
        Codon_change: tTATCAACTACAACGTGTCACGGTCTTCAGAAATATTTCCAGATAATACTACCAGTTACTGATTGGAGTATAGAGTCTAACAGGAGTGCTCTCAATATTATTCTACGACGATTAGACAAAACACTATCCAAGATTGCCAAACGTCAAAGTTTTCGAAAAAGAGCT/tGCCAAACGTCAAAGTTTTCGAAAAAGAGCA
        Amino_acid_change: LSTTTCHGLQKYFQIILPVTDWSIESNRSALNIILRRLDKTLSKIAKRQSFRKRA/CQTSKFSKKSX
  Isolation: Mutagen: TMP/UV
  Genetics: Map: V
  Description: Phenotype_not_observed: WBPhenotype:0000062 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Classified as homozygous viable by the National BioResource Project of Japan. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
  Remark: 19215/19216-GCCAAACGTCAAAGTTTTCGAAAAAGAGCA-19379/19380 (164 bp deletion + 30 bp insertion)
    This knockout was generated by the National Bioresource Project, Tokyo, Japan, which is part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence: WBPaper00041807
  Method: NBP_knockout_allele