WormBase Tree Display for Gene: WBGene00000608

WBGene00000608 SMap: S_parent: Sequence: ZK1193
  Identity: Version: 1
    Name: CGC_name: col-19 Person_evidence: WBPerson345
      Sequence_name: ZK1193.1
      Molecular_name: ZK1193.1
        ZK1193.1.1
        CE05126
      Other_name: col19 Accession_evidence: EMBL M25481
        CELE_ZK1193.1 Accession_evidence: NDB BX284606
      Public_name: col-19
    DB_info: Database: WormQTL gene WBGene00000608
        WormFlux gene WBGene00000608
        NDB locus_tag CELE_ZK1193.1
        Panther gene CAEEL|WormBase=WBGene00000608|UniProtKB=P18835
          family PTHR24637
        NCBI gene 180397
        RefSeq protein NM_001038488.6
        SwissProt UniProtAcc P18835
        TREEFAM TREEFAM_ID TF319043
        UniProt_GCRP UniProtAcc P18835
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:21 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: col
    Allele (25)
    Legacy_information: [C.elegansII] NMK. Transcript present in dauer, adult;not detected in egg or L4. Encodes collagen,col-8 family. [Cox and Hirsh 1985; Liu et al. 1995; VT]
    Strain: WBStrain00007918
      WBStrain00007932
      WBStrain00007933
      WBStrain00033323
      WBStrain00034928
    RNASeq_FPKM (74)
    GO_annotation (18)
    Ortholog (50)
    Paralog (165)
    Structured_description: Concise_description: col-19 encodes a member of the collagen superfamily containing collagen triple helix repeats (20 copies) that is required for normal structure of the alae; expressed during the L2-to-dauer and L4-to-adult molts with strongest expression in adult animals. Paper_evidence: WBPaper00000748
            WBPaper00002222
            WBPaper00005747
          Curator_confirmed: WBPerson48
          Date_last_updated: 01 Sep 2004 00:00:00
      Automated_description: A structural constituent of collagen and cuticulin-based cuticle. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle. Located in alae of collagen and cuticulin-based cuticle extracellular matrix and annuli extracellular matrix. Expressed in cuticle; hyp7 syncytium; syncytium; vulva; and in male. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: ZK1193.1
    Corresponding_CDS_history: ZK1193.1a:wp145
      ZK1193.1b:wp145
    Corresponding_transcript: ZK1193.1.1
    Other_sequence (62)
    Associated_feature: WBsf235261
      WBsf235262
  Experimental_info: RNAi_result (14)
    Expr_pattern (13)
    Drives_construct (40)
    Construct_product: WBCnstr00000750
      WBCnstr00004851
      WBCnstr00010258
      WBCnstr00011689
      WBCnstr00012421
      WBCnstr00037431
    Microarray_results (21)
    Expression_cluster: WBPaper00027339:daf-12(rh273)_downregulated
      WBPaper00032031:DConiospora_downregulated_OligoArray_24h
      WBPaper00033070:Elbe_upregulated
      WBPaper00033444:BacteriaDiet_regulated
      WBPaper00036738:4uM_Heme_upregulated
      WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:AVE-neuron_L1-larva_expressed
      WBPaper00037950:bodywall-muscle_embryo_enriched
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:CEP-sheath-cells_adult_enriched
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:hypodermis_larva_enriched
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00038237:age-1_upregulated_intestine_rescue
      WBPaper00038237:age-1_upregulated_neuron_rescue
      WBPaper00038237:age-1_upregulated_nontransgenic
      WBPaper00040990:PA14_downregulated
      WBPaper00041954:ethanol_upregulated
      WBPaper00042215:wdr-23(tm1817)_downregulated
      WBPaper00042477:rsr-2(RNAi)_downregulated_TilingArray
      WBPaper00044246:pgrn-1_ced-1_downregulated
      WBPaper00044316:CH3HgCl_7.5uM_downregulated
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044557:DietaryRestriction_downregulated
      WBPaper00044578:reduced-humidity_downregulated_microarray
      WBPaper00044736:rising_dev_expression
      WBPaper00045017:blmp-1(tm548)_downregulated
      WBPaper00045316:prg-1_downregulated_L4
      WBPaper00045316:prg-1_upregulated_L1
      WBPaper00045401:N.parisii_64h_downregulated
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_upregulated
      WBPaper00045861:wdr-5(ok1417)_downregulated
      WBPaper00046012:tdp-1(ok803)_downregulated
      WBPaper00046337:monosomal_N2_vs_daf-2_upregulated
      WBPaper00046337:polysomal_daf-2_vs_daf-2;daf-16_upregulated
      WBPaper00046337:polysomal_N2_vs_daf-2_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00046499:AMPK_regulated
      WBPaper00046805:P-granule-RNAi_upregulated_Set1
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00048611:MnCl2_downregulated
      WBPaper00048988:neuron_expressed
      WBPaper00049018:swsn-2.2(RNAi)_upregulated
      WBPaper00049495:starvation-refeeding_regulated
      WBPaper00049498:npr-1(ur89)_regulated_6
      WBPaper00049732:blmp-1(tm548)_vs_N2_upregulated
      WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031)
      WBPaper00049920:Glucose-Diet_upregulated_N2
      WBPaper00049942:HeatShock_upregulated_hsf-1(+)
      WBPaper00050080:rbr-2(tm3141)_upregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050522:mafr-1(tm6082)_downregulated
      WBPaper00050717:let-7(n2853)_lin-41(xe11)_downregulated
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00051404:alg-1(gk214)_upregulated
      WBPaper00051404:alg-2(ok304)_upregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053318:Aging_downregulated_mRNA_N2
      WBPaper00053318:mir-71(n4115)_downregulated_mRNA
      WBPaper00053388:dauer_regulated_Cluster4
      WBPaper00053402:cco-1(RNAi)_downregulated
      WBPaper00053599:female_vs_male_downregulated
      WBPaper00053599:oocyte_vs_mitosis_upregulated
      WBPaper00053713:Pheromone-induced_postdauer_vs_control_downregulated
      WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00053814:15C_downregulated_PY79
      WBPaper00054410:set-26(tm2467)_downregulated
      WBPaper00054810:deoxynivalenol_downregulated
      WBPaper00055013:hmg-3(bar24)_upregulated
      WBPaper00055049:S.gordonii_downregulated
      WBPaper00055060:flr-1(RNAi)_downregulated
      WBPaper00055103:thoc-5(wy822)_downregulated
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Psora_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin-Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Psora_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rapamycin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin-Psora_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055827:pfd-6(gk493446)_downregulated
      WBPaper00055941:atfs-1(et15)_downregulated
      WBPaper00055941:nuo-6(qm200)_upregulated
      WBPaper00055944:C.butyricum_vs_OP50_downregulated
      WBPaper00055969:electromagnetic-field_upregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056039:efa-6(tm3124)_upregulated
      WBPaper00056039:hda-6(ok3203)_upregulated
      WBPaper00056039:ptl-1(ok621)_downregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_downregulated_N2
      WBPaper00056139:soil-microbiota_downregulated
      WBPaper00056169:rrf-3(pk1426)_upregulated_L4
      WBPaper00056218:daf-16(mu86)_downregulated_Day5
      WBPaper00056284:ints-6(t1903)_upregulated
      WBPaper00056290:hsp-6(mg585)_downregulated
      WBPaper00056290:mdt-15(mg584)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056586:mpk-2(ok219)_upregulated
      WBPaper00056868:P.aeruginosa_downregulated_smallRNA
      WBPaper00057041:spc-1(cas971)_upregulated
      WBPaper00057041:unc-70(cas983)_upregulated
      WBPaper00057068:Cadmium_downregulated
      WBPaper00057068:ints-4(RNAi)_downregulated
      WBPaper00057068:ints-4(RNAi)_downregulated_Cadmium
      WBPaper00057068:numr-1(RNAi)_upregulated
      WBPaper00057068:numr-1(RNAi)_upregulated_Cadmium
      WBPaper00058711:paraquat_upregulated
      WBPaper00058711:skn-1(lax188)_downregulated
      WBPaper00058945:mir-1(gk276)_downregulated
      WBPaper00058948:npr-8(ok1439)_downregulated_PA14
      WBPaper00058948:PA14_upregulated
      WBPaper00058958:100mGy-irradiation-72h_upregulated
      WBPaper00059191:hsp-16.2p-LIN-29_upregulated
      WBPaper00059253:stearic-acid_downregulated
      WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
      WBPaper00059334:sacy-1(depletion)_regulated
      WBPaper00059421:daf-1(m40);daf-3(mgDf90)_upregulated
      WBPaper00059421:daf-1(m40)_upregulated
      WBPaper00059735:glucose_upregulated_lpin-1(RNAi)
      WBPaper00059739:hira-1(gk835598)_downregulated_adult
      WBPaper00059763:neuron_acr-2(n2420gf)_regulated
      WBPaper00059824:rnp-6(dh1127)_regulated_OP50
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00059895:wounding_downregulated
      WBPaper00060084:cco-1(RNAi)_downregulated_lin-40(yth27)
      WBPaper00060100:SiNP_downregulated_mRNA
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
      WBPaper00060445:ikb-1(nr2027)_upregulated_L4
      WBPaper00060445:nfki-1(cer1)_ikb-1(nr2027)_upregulated_L4
      WBPaper00060445:nfki-1(cer1)_upregulated_L4
      WBPaper00060459:bcat-1(RNAi)_downregulated
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00060703:nas-38(ok3407)_downregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060909:atfs-1(cmh15)_upregulated
      WBPaper00060911:prx-5(RNAi)_downregulated_mRNA
      WBPaper00061081:E.faecalis_downregulated_N2
      WBPaper00061081:E.faecalis_downregulated_skpo-1(ok1640)
      WBPaper00061274:hypergravity_15xg_upregulated
      WBPaper00061340:B_F_K_Kp_U_Y
      WBPaper00061341:28C_24h_downregulated
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061478:pie-1(ne4433)_upregulated
      WBPaper00061479:hda-1(ne4747)_upregulated
      WBPaper00061479:mep-1(ne4629)_upregulated
      WBPaper00061479:prg-1(tm872)_upregulated
      WBPaper00061479:ubc-9(ne4833)_upregulated
      WBPaper00061527:col-178-col-19
      WBPaper00061530:nhr-49(e2144)_downregulated
      WBPaper00061651:AMso_enriched
      WBPaper00061692:acivicin_downregulated
      WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062197:mec-8_upregulated
      WBPaper00062354:H.zoospora_6h_regulated
      WBPaper00062354:H.zoospora_12h_regulated
      WBPaper00062440:crh-1(n3315)_upregulated
      WBPaper00062440:crh-1(syb385)_upregulated
      WBPaper00062446:nhr-8(hd117)_downregulated
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00063976:micu-1(bon20)_upregulated
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064130:Beta-Amyloid_24h_upregulated_mRNA
      WBPaper00064494:postdauer_downregulated_WholeAnimal
      WBPaper00064532:pals-25(icb98)_upregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00064721:fasn-1(g14)_upregulated_starved
      WBPaper00064727:daf-2(e1370)_upregulated
      WBPaper00064735:mys-1(RNAi)_vs_N2_upregulated
      WBPaper00064871:hypoxia_upregulated_F1
      WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
      WBPaper00065029:cadmium_downregulated
      WBPaper00065096:25C_vs_20C_upregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065096:npr-8(ok1439)_downregulated_Day10_20C
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065158:25C_vs_15C_downregulated_WholeAnimal
      WBPaper00065373:Cisplatin_downregulated_WT
      WBPaper00065392:Lb.reuteri_upregulated
      WBPaper00065392:P.pentosaceus_upregulated
      WBPaper00065581:hpk-1(pk1393)_upregulated
      WBPaper00065623:10
      WBPaper00065749:endu-2(tm4977)_downregulated
      WBPaper00065749:Heat-Shock_upregulated_endu-2(tm4977)
      WBPaper00065749:Heat-Shock_upregulated_N2
      WBPaper00065759:dot-1.1(knu339)_upregulated
      WBPaper00065835:Day5_vs_Day1_downregulated
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065835:mtH2S-AP39-D0-treatment_upregulated_Day11
      WBPaper00065975:P-body_vs_oocyte_depleted
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065984:pals-17(syb3980)_upregulated
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066110:tetraploid_vs_diploid_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      cgc4386_cluster_1_1
      cgc4489_group_2
      WBPaper00005124:testosterone_10-9M_regulated
      WBPaper00025099:MA_specific
      WBPaper00026929:Resveratrol_regulated_daf-16
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00030985:Enterococcus_faecalis_downregulated
      WBPaper00030985:Photorhabdus_luminescens_downregulated
      WBPaper00031060:2-deoxy-D-glucose_upregulated
      WBPaper00031184:acrylamide_upregulated
      WBPaper00031703:heme_responsive_2
      WBPaper00032062:age_regulated_genes
      WBPaper00036130:mir-243_down_regulated
      WBPaper00036286:Pattern_I
      WBPaper00036375:depleted_in_PVD_OLL
      WBPaper00037113:CPF_16C_down-regulated
      WBPaper00037113:DZN_16C_down-regulated
      WBPaper00038172:aak-2overexpression_up_regulated
      WBPaper00038172:tax-6null_up_regulated
      WBPaper00038462:aging_downregulated
      WBPaper00040210:Chlorpyrifos_16C_regulated
      WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated
      WBPaper00040210:Diazinon_24C_regulated
      WBPaper00040858:eQTL_age_regulated_aging
      WBPaper00040963:Q200_up
      WBPaper00041002:HF_11d_2.0mM_Up
      WBPaper00041002:HQ_3d_0.2mM_Up
      WBPaper00041174:environmental
      WBPaper00041174:environmental_prime
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_3h
      WBPaper00044535:male_downregulated
      WBPaper00045015:acs-3(ft5)_downregulated
      WBPaper00045015:nhr-25(RNAi)_downregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
      WBPaper00055899:nitroguanidine_regulated
      WBPaper00057098:SiO2-nanoparticles_downregulated
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_SM
    Interaction (298)
  Map_info: Map: X Position: -19.9103
    Positive: Positive_clone: ZK1193 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (68)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene