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WormBase Tree Display for Gene: WBGene00001064

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Name Class

WBGene00001064SMapS_parentSequenceT14B4
IdentityVersion1
NameCGC_namedpy-2Person_evidenceWBPerson261
Sequence_nameT14B4.6
Molecular_nameT14B4.6
T14B4.6.1
CE04953
Other_namerol-2
CELE_T14B4.6Accession_evidenceNDBBX284602
Public_namedpy-2
DB_infoDatabaseAceViewgene2H5
WormQTLgeneWBGene00001064
WormFluxgeneWBGene00001064
NDBlocus_tagCELE_T14B4.6
PanthergeneCAEEL|WormBase=WBGene00001064|UniProtKB=P35799
familyPTHR24637
NCBIgene174107
RefSeqproteinNM_062966.9
SwissProtUniProtAccP35799
UniProt_GCRPUniProtAccP35799
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:22WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classdpy
Reference_alleleWBVar00142906
Allele (30)
Legacy_informatione8 : dumpy left roller; early larvae non-dumpy. ES3 ME1. NA > 10 (e115 sc38ts sc78sd e489 (pka rol-2) etc.).
See dpy-2.
See also e115, e487, e489, e961, e1280, e1359
[C.elegansII] e8 : dumpy left roller; early larvae non-dumpy. Suppresses some alleles of glp-1, emb-5. ES3 ME1. OA>10: e115, sc38ts, sc78sd,e489 (pka rol-2), e961, q292 etc. Cloned: encodes collagen, 41% identical to adjacent gene dpy-10. [Brenner 1974; Levy et al. 1993; CH]
Strain (15)
RNASeq_FPKM (74)
GO_annotation00044941
00044942
00044943
00044944
00044945
00044946
00044947
00044948
00108188
Ortholog (29)
Paralog (162)
Structured_descriptionConcise_descriptionThe dpy-2 gene encodes an unusual cuticular collagen that is required for maintaining the normal body length of the animal in later larval stages; dpy-2 interacts with other cuticular collagens such as dpy-10 and sqt-1, and suppresses mutations in glp-1, mup-1, and emb-5.Paper_evidenceWBPaper00001792
WBPaper00003853
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to be a structural constituent of collagen and cuticulin-based cuticle. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle; post-embryonic body morphogenesis; and regulation of growth. Predicted to be part of collagen trimer. Expressed in head neurons and pharynx. Used to study skin disease.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:37Homo sapiensPaper_evidenceWBPaper00061220
Curator_confirmedWBPerson324
Date_last_updated02 May 2022 00:00:00
Models_disease_in_annotationWBDOannot00001173
Molecular_infoCorresponding_CDST14B4.6
Corresponding_transcriptT14B4.6.1
Other_sequence (15)
Associated_featureWBsf644316
WBsf657711
WBsf221491
WBsf221492
Experimental_infoRNAi_result (23)
Expr_patternExpr4481
Expr4482
Expr1024298
Expr1030673
Expr1156898
Expr2011070
Expr2029307
Drives_constructWBCnstr00012049
WBCnstr00012050
WBCnstr00037107
Construct_productWBCnstr00037107
Microarray_results (20)
Expression_cluster (271)
Interaction (192)
WBProcessWBbiopr:00000124
Map_infoMapIIPosition0.042787Error0.009724
Well_ordered
PositiveInside_rearrarDp2
Positive_cloneT14B4Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_data2_point36
47
217
6101
7051
Multi_point (17)
Pos_neg_data (22)
Reference (73)
MethodGene