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WormBase Tree Display for Gene: WBGene00001069

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Name Class

WBGene00001069SMapS_parentSequenceF46C8
IdentityVersion1
NameCGC_namedpy-7Person_evidenceWBPerson261
Sequence_nameF46C8.6
Molecular_nameF46C8.6
F46C8.6.1
CE04580
Other_nameCELE_F46C8.6Accession_evidenceNDBBX284606
Public_namedpy-7
DB_infoDatabaseAceViewgeneXI156
WormQTLgeneWBGene00001069
WormFluxgeneWBGene00001069
NDBlocus_tagCELE_F46C8.6
NCBIgene181013
RefSeqproteinNM_076873.7
SwissProtUniProtAccP34688
UniProt_GCRPUniProtAccP34688
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:22WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classdpy
Reference_alleleWBVar00142953
Allele (41)
Possibly_affected_byWBVar02154063
Legacy_informatione88 : dumpy (non-roller) ES3. ME1. NA8 (e1324ts sc27ts : left roller dumpy etc.).
[C.elegansII] e88 : dumpy (non-roller). Suppresses some alleles of glp-1, emb-5.ES3. ME1. OA>8: e1324ts, sc27ts (left roller dumpy), m38, e2076, q288, etc. Cloned: transspliced to SL1; encodes typical cuticular collagen, 318aa, no close relatives; 4 missense alleles sequenced; expressed at each larval stage 5.5 hours pre-lethargus. [Johnstone et al. 1992; IA]
StrainWBStrain00023947
WBStrain00026736
WBStrain00026840
WBStrain00026854
WBStrain00003792
WBStrain00004301
WBStrain00004095
WBStrain00006165
WBStrain00006338
WBStrain00007960
RNASeq_FPKM (74)
GO_annotation (12)
Ortholog (20)
Paralog (162)
Structured_descriptionConcise_descriptiondpy-7 encodes a cuticular collagen; DPY-7 functions as a structural constituent of the extracellular cuticle whose activity is required for normal cuticular morphology and hence, proper body form.Paper_evidenceWBPaper00001618
Curator_confirmedWBPerson1843
Date_last_updated21 Sep 2005 00:00:00
Automated_descriptionA structural constituent of collagen and cuticulin-based cuticle. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle and post-embryonic body morphogenesis. Located in annular furrow extracellular matrix. Expressed in several structures, including P1; P12; P2; cuticle; and hypodermis. Used to study skin disease.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:37Homo sapiensPaper_evidenceWBPaper00061220
Curator_confirmedWBPerson324
Date_last_updated02 May 2022 00:00:00
Models_disease_assertedWBDOannot00001175
Molecular_info (4)
Experimental_infoRNAi_result (38)
Expr_pattern (13)
Drives_construct (124)
Construct_productWBCnstr00012412
WBCnstr00012449
WBCnstr00016584
WBCnstr00037102
Regulate_expr_clusterWBPaper00053771:down_by_skn-1(RNAi)_at_dpy-7(e88)
WBPaper00053771:up_at_dpy-7(e88)
AntibodyWBAntibody00000615
WBAntibody00001857
Microarray_results (20)
Expression_cluster (292)
Interaction (202)
WBProcessWBbiopr:00000124
Map_infoMapXPosition-1.6004Error0.006854
Well_ordered
PositivePositive_cloneF46C8Inferred_automaticallyFrom sequence, transcript, pseudogene data
IJ#L3AT1
Mapping_data2_point (23)
Multi_point (69)
Pos_neg_data (23)
Reference (152)
MethodGene