WBGene00001073 | Evidence | CGC_data_submission |
| SMap | S_parent | Sequence | F46E10 |
| Identity | Version | 1 |
| | Name | CGC_name | dpy-11 | Person_evidence | WBPerson261 |
| | | Sequence_name | F46E10.9 |
| | | Molecular_name | F46E10.9 |
| | | | F46E10.9.1 |
| | | | CE20819 |
| | | | F46E10.9.2 |
| | | Other_name | CELE_F46E10.9 | Accession_evidence | NDB | BX284605 |
| | | Public_name | dpy-11 |
| | DB_info | Database | AceView | gene | 5G992 |
| | | | WormQTL | gene | WBGene00001073 |
| | | | WormFlux | gene | WBGene00001073 |
| | | | NDB | locus_tag | CELE_F46E10.9 |
| | | | Panther | gene | CAEEL|WormBase=WBGene00001073|UniProtKB=G5EC91 |
| | | | | family | PTHR46107 |
| | | | NCBI | gene | 179040 |
| | | | RefSeq | protein | NM_001383321.2 |
| | | | TREEFAM | TREEFAM_ID | TF106376 |
| | | | TrEMBL | UniProtAcc | G5EC91 |
| | | | UniProt_GCRP | UniProtAcc | G5EC91 |
| | Species | Caenorhabditis elegans |
| | History | Version_change | 1 | 07 Apr 2004 11:29:22 | WBPerson1971 | Event | Imported | Initial conversion from geneace |
| | Status | Live |
| Gene_info | Biotype | SO:0001217 |
| | Gene_class | dpy |
| | Reference_allele | WBVar00143044 |
| | Allele (97) |
| | Legacy_information | e224 : medium dumpy. ES3 (adult) ES2 (larvae). ME2. NA > 10 (e33 e1180icr (these and most other alleles have much stronger dumpy ('piggy') phenotype) etc.). |
| | | See also e33, e752, e1180, e1194, s360 |
| | | [C.elegansII] e224 : medium dumpy. ES3 (adult) ES2 (larvae). ME2. Males Ram (lumpy rays) at25C. OA>10: e33, e1180icr (these and most other alleles have much stronger dumpy or 'piggy' phenotype) etc.), e455,e733, e752, s287 (induced on eT1), s10, s261, s360fdi etc. [Brenner 1974; Baird and Emmons 1990; CB] |
| | Strain (139) |
| | RNASeq_FPKM (74) |
| | GO_annotation | 00011338 |
| | | 00011339 |
| | | 00011340 |
| | | 00011341 |
| | | 00011342 |
| | | 00011343 |
| | | 00011344 |
| | | 00011345 |
| | | 00011346 |
| | Contained_in_operon | CEOP5120 |
| | Ortholog (41) |
| | Paralog (14) |
| | Structured_description | Automated_description | Enables protein-disulfide reductase activity. Involved in several processes, including cuticle development involved in collagen and cuticulin-based cuticle molting cycle; post-embryonic body morphogenesis; and protein folding. Located in endomembrane system. Expressed in several structures, including R1_hyp; R2_hyp; R3_hyp; R4_hyp; and R5_hyp. Is an ortholog of human TMX1 (thioredoxin related transmembrane protein 1). | Paper_evidence | WBPaper00065943 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | | WBPerson37462 |
| | | | | Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase |
| | | | | Date_last_updated | 29 Nov 2023 00:00:00 |
| Molecular_info | Corresponding_CDS | F46E10.9 |
| | Corresponding_transcript | F46E10.9.1 |
| | | F46E10.9.2 |
| | Other_sequence (67) |
| | Associated_feature (20) |
| Experimental_info | RNAi_result (20) |
| | Expr_pattern | Chronogram1745 |
| | | Expr1854 |
| | | Expr1855 |
| | | Expr6089 |
| | | Expr13275 |
| | | Expr1026593 |
| | | Expr1030681 |
| | | Expr1151367 |
| | | Expr2011056 |
| | | Expr2029293 |
| | Drives_construct | WBCnstr00002463 |
| | | WBCnstr00010487 |
| | | WBCnstr00010488 |
| | | WBCnstr00042718 |
| | Construct_product | WBCnstr00010488 |
| | Microarray_results (22) |
| | Expression_cluster | WBPaper00029359_1124 |
| | | WBPaper00029359_1141 |
| | | WBPaper00029359_1227 |
| | | WBPaper00029359_1280 |
| | | WBPaper00029359_1304 |
| | | WBPaper00029359_1351 |
| | | WBPaper00029359_1444 |
| | | WBPaper00029359_1497 |
| | | WBPaper00029359_1504 |
| | | WBPaper00029359_1525 |
| | | WBPaper00029359_1604 |
| | | WBPaper00029359_1682 |
| | | WBPaper00032528:L3_enriched |
| | | WBPaper00033065:cyc-1(RNAi)_downregulated |
| | | WBPaper00036375:enriched_in_PVD_OLL |
| | | WBPaper00037055:DAF-16_binding_DNA |
| | | WBPaper00037950:CEP-sheath-cells_adult_enriched |
| | | WBPaper00037950:CEP-sheath-cells_adult_SelectivelyEnriched |
| | | WBPaper00037950:coelomocytes_L2-larva_expressed |
| | | WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed |
| | | WBPaper00037950:hypodermis_CoreEnriched |
| | | WBPaper00037950:hypodermis_embryo_enriched |
| | | WBPaper00037950:hypodermis_embryo_SelectivelyEnriched |
| | | WBPaper00037950:hypodermis_L3-L4-larva_expressed |
| | | WBPaper00037950:hypodermis_larva_enriched |
| | | WBPaper00037950:hypodermis_larva_SelectivelyEnriched |
| | | WBPaper00038118:stress_upregulated_N2 |
| | | WBPaper00038289:oocyte_protein |
| | | WBPaper00040221:DAF-12_target_ALF4 |
| | | WBPaper00040965:lipid-droplet_associated_protein |
| | | WBPaper00042477:rsr-2(RNAi)_downregulated_RNAseq |
| | | WBPaper00043945:MeHg_upregulated |
| | | WBPaper00044128:daf-2(e1370)_upregulated |
| | | WBPaper00044501:gld-1_let-7_regulated |
| | | WBPaper00044736:oscillating_dev_expression |
| | | WBPaper00044746:aging_downregulated_HeatShock |
| | | WBPaper00044760:somatic_specific |
| | | WBPaper00045257:bar-1(ga80)_downregulated |
| | | WBPaper00045521:Gender_Neutral |
| | | WBPaper00045774:clk-1_downregulated |
| | | WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h |
| | | WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h |
| | | WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h |
| | | WBPaper00046497:B.thuringiensis_downregulated_protein |
| | | WBPaper00046887:WNT-target |
| | | WBPaper00048988:neuron_expressed |
| | | WBPaper00050344:PLM-neuron_enriched |
| | | WBPaper00050488:adult_vs_dauer_regulated_N2_20C |
| | | WBPaper00050686:glp-1(e2141)_upregulated |
| | | WBPaper00050698:DEP-1_interacting |
| | | WBPaper00050726:OsmoticStress_regulated_Food |
| | | WBPaper00050726:OsmoticStress_regulated_NoFood |
| | | WBPaper00050801:DPY-21_dauer_regulome |
| | | WBPaper00050990:arcade_intestinal-valve_expressed |
| | | WBPaper00050990:body-muscle_expressed |
| | | WBPaper00050990:GABAergic-neuron_expressed |
| | | WBPaper00050990:hypodermis_expressed |
| | | WBPaper00050990:intestine_expressed |
| | | WBPaper00050990:pharynx_expressed |
| | | WBPaper00050990:seam_expressed |
| | | WBPaper00051039:germline_enriched |
| | | WBPaper00051245:epidermis_cytoplasm_expressed |
| | | WBPaper00051245:epidermis_nucleus_expressed |
| | | WBPaper00051245:intestine_cytoplasm_expressed |
| | | WBPaper00051265:F4_hrde-1(tm1200)_upregulated |
| | | WBPaper00051265:F4_morc-1(tm6048)_upregulated |
| | | WBPaper00051404:alg-1(gk214)_downregulated |
| | | WBPaper00051404:alg-2(ok304)_downregulated |
| | | WBPaper00053388:dauer_regulated_Cluster3 |
| | | WBPaper00053810:nuo-6(qm200)_downregulated |
| | | WBPaper00054410:set-9(rw5)_downregulated |
| | | WBPaper00054410:set-26(tm2467)_downregulated |
| | | WBPaper00054493:hpl-2(tm1489)_upregulated |
| | | WBPaper00055013:hmg-3(bar24)_downregulated |
| | | WBPaper00055049:S.gordonii_upregulated |
| | | WBPaper00055354:Rapamycin-Metformin_upregulated |
| | | WBPaper00055354:Rapamycin-Rifampicin_upregulated |
| | | WBPaper00055626:pry-1(mu38)_upregulated |
| | | WBPaper00055648:germline_expressed |
| | | WBPaper00055827:pfd-6(gk493446)_upregulated |
| | | WBPaper00055941:atfs-1(et15)_upregulated |
| | | WBPaper00055971:nhl-2(ok818)_25C_upregulated |
| | | WBPaper00056169:rrf-3(pk1426)_downregulated_L4 |
| | | WBPaper00056275:P.aeruginosa_downregulated |
| | | WBPaper00056284:ints-5(RNAi)_downregulated |
| | | WBPaper00056290:hsp-6(mg585)_upregulated |
| | | WBPaper00056290:mdt-15(mg584)_upregulated |
| | | WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated |
| | | WBPaper00056471:S.aureus-4h_downregulated_N2 |
| | | WBPaper00057041:spc-1(cas971)_upregulated |
| | | WBPaper00057041:unc-70(cas983)_upregulated |
| | | WBPaper00057068:numr-1(RNAi)_downregulated |
| | | WBPaper00057154:HeatShock_upregulated_mRNA |
| | | WBPaper00057288:iff-1(RNAi)_upregulated_transcript |
| | | WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA |
| | | WBPaper00059328:mrps-5(RNAi)_downregulated_protein |
| | | WBPaper00060084:cco-1(RNAi)_downregulated_N2 |
| | | WBPaper00060224:atf-6(ok551)_upregulated |
| | | WBPaper00060811:L1_vs_adult_downregulated_neural |
| | | WBPaper00060909:atfs-1(cmh15)_downregulated |
| | | WBPaper00061340:G2_and_W_blasts |
| | | WBPaper00061340:hyp4_hyp5_hyp6 |
| | | WBPaper00061340:hyp7_AB_lineage |
| | | WBPaper00061340:hyp7_C_lineage |
| | | WBPaper00061340:K_Kprime |
| | | WBPaper00061340:Parents_of_PHsh_hyp8_hyp9 |
| | | WBPaper00061340:P_cell |
| | | WBPaper00061340:T |
| | | WBPaper00061439:unc-30(ok613)_upregulated |
| | | WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection |
| | | WBPaper00061478:SUMO-conjugated_protein |
| | | WBPaper00061527:mlt-9_22518-F33D4.6_14044 |
| | | WBPaper00061527:uggt-1_21889-tag-320_20312 |
| | | WBPaper00061651:Rectal_gland_enriched |
| | | WBPaper00062118:neural-HSF-1_downregulated |
| | | WBPaper00062325:muscle_enriched_coding-RNA |
| | | WBPaper00062354:H.zoospora_6h_regulated |
| | | WBPaper00062446:nhr-8(hd117)_upregulated |
| | | WBPaper00062456:doxycycline_upregulated_CB4856_protein |
| | | WBPaper00062554:MAGU-2_interacting |
| | | WBPaper00062669:extracellular-vesicle_protein |
| | | WBPaper00064071:NHR-49_interacting |
| | | WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20) |
| | | WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141) |
| | | WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20) |
| | | WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141) |
| | | WBPaper00064201:SNA-3_interacting |
| | | WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated |
| | | WBPaper00064532:pals-25(icb98)_downregulated |
| | | WBPaper00064952:Day1_vs_L4_downregulated_25C |
| | | WBPaper00064952:Day5_vs_L4_downregulated_20C |
| | | WBPaper00064952:Day5_vs_L4_downregulated_25C |
| | | WBPaper00064952:Day10_vs_L4_downregulated_20C |
| | | WBPaper00064952:Day10_vs_L4_downregulated_25C |
| | | WBPaper00064992:Eugenol_upregulated |
| | | WBPaper00065096:25C_vs_20C_downregulated |
| | | WBPaper00065096:Day10_vs_Day1_downregulated |
| | | WBPaper00065120:body-muscle-transcriptome |
| | | WBPaper00065373:Cisplatin_downregulated_WT |
| | | WBPaper00065945:epidermis-rpoa-2(-)_downregulated_protein |
| | | WBPaper00065975:P-body_vs_WholeAnimal_enriched |
| | | cgc4386_cluster_4_6 |
| | | cgc4489_group_6 |
| | | WBPaper00005124:estrogen_10-5M_regulated |
| | | WBPaper00025032:cluster_164 |
| | | WBPaper00025141:N2_Expressed_Genes |
| | | WBPaper00025141:unc-4::GFP_Expressed_Genes |
| | | WBPaper00026980:intestine_enriched |
| | | WBPaper00030985:Enterococcus_faecalis_downregulated |
| | | WBPaper00031003:0hr_muscle_depleted |
| | | WBPaper00031003:total_muscle_depleted |
| | | WBPaper00031532:Larva_Pan_Neuronal_Depleted |
| | | WBPaper00031832:slr-2_regulated |
| | | WBPaper00032165:differentially_expressed_with_age_medoid_1 |
| | | WBPaper00032948:FedUp |
| | | WBPaper00034739:N2lessDR1350 |
| | | WBPaper00035588:alg-1(-)_upregulated |
| | | WBPaper00036130:mir-243_up_regulated |
| | | WBPaper00036286:Pattern_G |
| | | WBPaper00038172:tax-6null_down_regulated |
| | | WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2 |
| | | WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.5 |
| | | WBPaper00041002:HF_3d_2.0mM_Down |
| | | WBPaper00041207:CE_dauer_down |
| | | WBPaper00041606:CE_X.nematophila_regulated |
| | | WBPaper00041939:control_vs_EtBr-exposed_48h |
| | | WBPaper00041939:control_vs_EtBr-exposed_51h |
| | | WBPaper00041939:control_vs_UVC-EtBr-exposed_48h |
| | | WBPaper00041939:control_vs_UVC-EtBr-exposed_51h |
| | | WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h |
| | | WBPaper00041939:EtBr-exposed_vs_UVC-exposed_51h |
| | | WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h |
| | | WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h |
| | | WBPaper00042128:gei-8(ok1671)_downregulated |
| | | WBPaper00042178:hlh-29(tm284)_downregulated |
| | | WBPaper00042331:a-SWCNTs_downregulated |
| | | WBPaper00045263:0.1mM-paraquat_upregulated |
| | | WBPaper00045263:isp-1(qm150)_upregulated |
| | | WBPaper00045263:nuo-6(qm200)_upregulated |
| | | WBPaper00045263:ProLongevity-mtROS_upregulated |
| | | WBPaper00046548:dafachronic-acid_upregulated |
| | | WBPaper00047070:N2_starvation_downregulated |
| | | WBPaper00048989:eat-2(ad465)_rapamycin_downregulated |
| | | WBPaper00048989:N2_rapamycin_upregulated |
| | | WBPaper00053236:Starvation_regulated_GR1307 |
| | | WBPaper00053236:Starvation_regulated_N2 |
| | | [cgc5767]:expression_class_E |
| | | [cgc5767]:expression_class_E_pi(23_min) |
| | | [cgc5767]:expression_class_M |
| | | [cgc5767]:expression_class_ME |
| | | [cgc6390]:Cluster_B |
| | | [cgc6390]:mixed_oogenesis-somatic |
| | Interaction (155) |
| | WBProcess | WBbiopr:00000124 |
| Map_info | Map | V | Position | 0 |
| | Well_ordered |
| | Positive | Inside_rearr | sDf20 |
| | | | sDf30 |
| | | | nDf1 |
| | | | nDf18 |
| | | | rT1 |
| | | Positive_clone | F46E10 | Inferred_automatically | From sequence, transcript, pseudogene data |
| | | | T04F11 |
| | Negative | Outside_rearr | sDf36 |
| | | | eDf1 |
| | | | nDf42 |
| | | Negative_clone | W01A11 |
| | Mapping_data | 2_point (100) |
| | | Multi_point (259) |
| | | Pos_neg_data (15) |
| | Landmark_gene |
| Reference (113) |
| Remark | Julia Pak rescued dpy-11 with T04F11 when she was a rotation student in my lab. |
| | Sequence connection from [Ko F] |
| Method | Gene |