WormBase Tree Display for Gene: WBGene00001073

WBGene00001073 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: F46E10
  Identity: Version: 1
    Name: CGC_name: dpy-11 Person_evidence: WBPerson261
      Sequence_name: F46E10.9
      Molecular_name: F46E10.9
        F46E10.9.1
        CE20819
        F46E10.9.2
      Other_name: CELE_F46E10.9 Accession_evidence: NDB BX284605
      Public_name: dpy-11
    DB_info: Database: AceView gene 5G992
        WormQTL gene WBGene00001073
        WormFlux gene WBGene00001073
        NDB locus_tag CELE_F46E10.9
        Panther gene CAEEL|WormBase=WBGene00001073|UniProtKB=G5EC91
          family PTHR46107
        NCBI gene 179040
        RefSeq protein NM_001383321.2
        TREEFAM TREEFAM_ID TF106376
        TrEMBL UniProtAcc G5EC91
        UniProt_GCRP UniProtAcc G5EC91
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:22 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: dpy
    Reference_allele: WBVar00143044
    Allele (97)
    Legacy_information: e224 : medium dumpy. ES3 (adult) ES2 (larvae). ME2. NA > 10 (e33 e1180icr (these and most other alleles have much stronger dumpy ('piggy') phenotype) etc.).
      See also e33, e752, e1180, e1194, s360
      [C.elegansII] e224 : medium dumpy. ES3 (adult) ES2 (larvae). ME2. Males Ram (lumpy rays) at25C. OA>10: e33, e1180icr (these and most other alleles have much stronger dumpy or 'piggy' phenotype) etc.), e455,e733, e752, s287 (induced on eT1), s10, s261, s360fdi etc. [Brenner 1974; Baird and Emmons 1990; CB]
    Strain (139)
    RNASeq_FPKM (74)
    GO_annotation: 00011338
      00011339
      00011340
      00011341
      00011342
      00011343
      00011344
      00011345
      00011346
    Contained_in_operon: CEOP5120
    Ortholog (41)
    Paralog (14)
    Structured_description: Automated_description: Enables protein-disulfide reductase activity. Involved in several processes, including cuticle development involved in collagen and cuticulin-based cuticle molting cycle; post-embryonic body morphogenesis; and protein folding. Located in endomembrane system. Expressed in several structures, including R1_hyp; R2_hyp; R3_hyp; R4_hyp; and R5_hyp. Is an ortholog of human TMX1 (thioredoxin related transmembrane protein 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F46E10.9
    Corresponding_transcript: F46E10.9.1
      F46E10.9.2
    Other_sequence (67)
    Associated_feature (20)
  Experimental_info: RNAi_result (20)
    Expr_pattern: Chronogram1745
      Expr1854
      Expr1855
      Expr6089
      Expr13275
      Expr1026593
      Expr1030681
      Expr1151367
      Expr2011056
      Expr2029293
    Drives_construct: WBCnstr00002463
      WBCnstr00010487
      WBCnstr00010488
      WBCnstr00042718
    Construct_product: WBCnstr00010488
    Microarray_results (22)
    Expression_cluster (192)
    Interaction (155)
    WBProcess: WBbiopr:00000124
  Map_info: Map: V Position: 0
    Well_ordered
    Positive: Inside_rearr: sDf20
        sDf30
        nDf1
        nDf18
        rT1
      Positive_clone: F46E10 Inferred_automatically: From sequence, transcript, pseudogene data
        T04F11
    Negative: Outside_rearr: sDf36
        eDf1
        nDf42
      Negative_clone: W01A11
    Mapping_data: 2_point (100)
      Multi_point (259)
      Pos_neg_data (15)
    Landmark_gene
  Reference: WBPaper00000031
    WBPaper00000168
    WBPaper00000320
    WBPaper00000321
    WBPaper00000465
    WBPaper00000538
    WBPaper00000554
    WBPaper00000601
    WBPaper00001018
    WBPaper00001073
    WBPaper00001308
    WBPaper00001328
    WBPaper00001425
    WBPaper00001454
    WBPaper00001474
    WBPaper00001477
    WBPaper00001558
    WBPaper00001563
    WBPaper00001649
    WBPaper00001709
    WBPaper00001738
    WBPaper00001747
    WBPaper00001829
    WBPaper00001854
    WBPaper00001887
    WBPaper00001912
    WBPaper00002194
    WBPaper00003197
    WBPaper00004545
    WBPaper00004883
    WBPaper00005177
    WBPaper00005272
    WBPaper00005639
    WBPaper00005704
    WBPaper00005747
    WBPaper00005809
    WBPaper00006063
    WBPaper00006103
    WBPaper00006130
    WBPaper00006361
    WBPaper00010210
    WBPaper00010530
    WBPaper00011237
    WBPaper00011424
    WBPaper00011433
    WBPaper00013705
    WBPaper00013778
    WBPaper00013779
    WBPaper00013833
    WBPaper00013858
    WBPaper00013904
    WBPaper00014009
    WBPaper00014010
    WBPaper00014148
    WBPaper00014155
    WBPaper00014159
    WBPaper00014210
    WBPaper00014503
    WBPaper00014979
    WBPaper00015216
    WBPaper00015279
    WBPaper00015329
    WBPaper00015350
    WBPaper00015443
    WBPaper00015606
    WBPaper00015684
    WBPaper00015829
    WBPaper00015878
    WBPaper00015974
    WBPaper00015980
    WBPaper00015987
    WBPaper00016007
    WBPaper00016045
    WBPaper00016076
    WBPaper00016084
    WBPaper00016091
    WBPaper00016139
    WBPaper00016140
    WBPaper00016148
    WBPaper00016180
    WBPaper00016247
    WBPaper00016267
    WBPaper00016339
    WBPaper00016341
    WBPaper00016484
    WBPaper00016486
    WBPaper00016496
    WBPaper00016546
    WBPaper00017310
    WBPaper00017510
    WBPaper00017549
    WBPaper00018096
    WBPaper00018148
    WBPaper00018150
    WBPaper00018825
    WBPaper00019025
    WBPaper00019335
    WBPaper00019602
    WBPaper00022032
    WBPaper00023250
    WBPaper00027278
    WBPaper00027314
    WBPaper00029020
    WBPaper00029198
    WBPaper00030871
    WBPaper00038491
    WBPaper00043836
    WBPaper00044045
    WBPaper00053313
    WBPaper00053410
    WBPaper00053589
    WBPaper00055090
    WBPaper00064558
  Remark: Julia Pak rescued dpy-11 with T04F11 when she was a rotation student in my lab.
    Sequence connection from [Ko F]
  Method: Gene