WormBase Tree Display for Gene: WBGene00001518
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| WBGene00001518 | SMap | S_parent | Sequence | F47D12 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | gar-2 | Person_evidence | WBPerson32 | |||||
| Sequence_name | F47D12.1 | ||||||||
| Molecular_name (15) | |||||||||
| Other_name | acm-2 | Paper_evidence | WBPaper00027767 | ||||||
| From_analysis | WormAtlas | ||||||||
| CELE_F47D12.1 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | gar-2 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:24 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 10 Jun 2014 12:12:12 | WBPerson1983 | Event | Acquires_merge | WBGene00043340 | ||||
| Acquires_merge | WBGene00043340 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | gar | ||||||||
| Allele (131) | |||||||||
| Strain | WBStrain00003713 | ||||||||
| WBStrain00031470 | |||||||||
| WBStrain00022222 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (37) | |||||||||
| Ortholog (32) | |||||||||
| Paralog (20) | |||||||||
| Structured_description | Concise_description | gar-2 encodes a novel, seven transmembrane-domain G protein-coupled acetylcholine receptor (AChR); when expressed in Xenopus oocytes treated with acetylcholine, GAR-2 is able to activate a mammalian G protein-activated inwardly rectifying K+ (GIRK1) channel, but not other channels, suggesting that GAR-2 couples to G proteins of the Gi family; pharmacological analyses indicate, however, that GAR-2 exhibits properties distinct from mammalian muscarinic AChRs; gar-2 is expressed from mid-embryogenesis through adulthood with expression seen in ciliated head neurons, ventral cord neurons, and the HSN (hermaphrodite-specific neuron). | Paper_evidence | WBPaper00004388 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 02 Nov 2006 00:00:00 | ||||||||
| Automated_description | Enables G protein-coupled acetylcholine receptor activity. Involved in G protein-coupled receptor signaling pathway; negative regulation of cholinergic synaptic transmission; and response to xenobiotic stimulus. Located in axon. Expressed in neurons. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F47D12.1a | |||||||
| F47D12.1b | |||||||||
| F47D12.1c | |||||||||
| F47D12.1d | |||||||||
| F47D12.1e | |||||||||
| Corresponding_CDS_history | F47D12.1c:wp275 | ||||||||
| Corresponding_transcript | F47D12.1a.1 | ||||||||
| F47D12.1b.1 | |||||||||
| F47D12.1c.1 | |||||||||
| F47D12.1d.1 | |||||||||
| F47D12.1e.1 | |||||||||
| Other_sequence | JI221387.1 | ||||||||
| Dviv_isotig26799 | |||||||||
| GO251308.1 | |||||||||
| JI465005.1 | |||||||||
| CBC06005_1 | |||||||||
| FK808445.1 | |||||||||
| Associated_feature (15) | |||||||||
| Experimental_info | RNAi_result (11) | ||||||||
| Expr_pattern | Chronogram723 | ||||||||
| Expr1114 | |||||||||
| Expr8178 | |||||||||
| Expr8179 | |||||||||
| Expr10067 | |||||||||
| Expr1025714 | |||||||||
| Expr1030913 | |||||||||
| Expr1151485 | |||||||||
| Expr2011945 | |||||||||
| Expr2030182 | |||||||||
| Drives_construct | WBCnstr00004148 | ||||||||
| WBCnstr00009595 | |||||||||
| WBCnstr00009870 | |||||||||
| WBCnstr00010085 | |||||||||
| WBCnstr00013162 | |||||||||
| WBCnstr00015039 | |||||||||
| WBCnstr00036893 | |||||||||
| Construct_product | WBCnstr00001343 | ||||||||
| WBCnstr00036893 | |||||||||
| Microarray_results (49) | |||||||||
| Expression_cluster (178) | |||||||||
| Interaction | WBInteraction000126687 | ||||||||
| WBInteraction000126688 | |||||||||
| WBInteraction000177996 | |||||||||
| WBInteraction000316805 | |||||||||
| WBInteraction000446248 | |||||||||
| Map_info | Map | III | Position | -1.39824 | Error | 0.002289 | |||
| Positive | Positive_clone | F47D12 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4334 | |||||||
| 4407 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (31) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| [140610 pad] Gene was missing Acquires_merge Event history data so inferred from Acquires_merge tag. | |||||||||
| Method | Gene |
