WormBase Tree Display for Gene: WBGene00001518

WBGene00001518 SMap: S_parent: Sequence: F47D12
  Identity: Version: 2
    Name: CGC_name: gar-2 Person_evidence: WBPerson32
      Sequence_name: F47D12.1
      Molecular_name (15)
      Other_name: acm-2 Paper_evidence: WBPaper00027767
          From_analysis: WormAtlas
        CELE_F47D12.1 Accession_evidence: NDB BX284603
      Public_name: gar-2
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:24 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 10 Jun 2014 12:12:12 WBPerson1983 Event: Acquires_merge: WBGene00043340
      Acquires_merge: WBGene00043340
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: gar
    Allele: WBVar02149055 Inferred_automatically: From strain object: JD269
      WBVar00399588
      WBVar00399589
      WBVar01995352
      WBVar00399590
      WBVar00399591
      WBVar01995353
      WBVar01995354
      WBVar00399592
      WBVar00399593
      WBVar00399594
      WBVar00399595
      WBVar00399596
      WBVar01500260
      WBVar00399597
      WBVar00399598
      WBVar00399599
      WBVar00399600
      WBVar00399601
      WBVar00091807
      WBVar01952266
      WBVar01952267
      WBVar01264312
      WBVar00299784
      WBVar01264313
      WBVar00299785
      WBVar01264314
      WBVar01264315
      WBVar01264316
      WBVar01827672
      WBVar01264318
      WBVar01264319
      WBVar02049706
      WBVar01607079
      WBVar00832858
      WBVar00832859
      WBVar00832860
      WBVar01494604
      WBVar00832861
      WBVar00832862
      WBVar01408720
      WBVar01893513
      WBVar00832863
      WBVar00832864
      WBVar00832865
      WBVar00832866
      WBVar00832867
      WBVar00832868
      WBVar00832869
      WBVar00832870
      WBVar00832871
      WBVar00832872
      WBVar00832873
      WBVar00832874
      WBVar00832875
      WBVar00832876
      WBVar00832877
      WBVar00832878
      WBVar02041317
      WBVar00832879
      WBVar00832880
      WBVar00832881
      WBVar00832882
      WBVar00832883
      WBVar00832884
      WBVar00832885
      WBVar00832886
      WBVar00832887
      WBVar00832888
      WBVar00832889
      WBVar00832890
      WBVar00832891
      WBVar01722608
      WBVar00832892
      WBVar00832893
      WBVar00832894
      WBVar00832895
      WBVar00832896
      WBVar00832897
      WBVar00832898
      WBVar00832899
      WBVar00832900
      WBVar00832901
      WBVar00832902
      WBVar00832903
      WBVar00832904
      WBVar01645027
      WBVar00832905
      WBVar01645028
      WBVar00832906
      WBVar00832907
      WBVar01999652
      WBVar00832908
      WBVar00832909
      WBVar02132142
      WBVar00832910
      WBVar00832911
      WBVar02132143
      WBVar00832912
      WBVar02132144
      WBVar02132145
      WBVar00832913
      WBVar02132146
      WBVar00832914
      WBVar02132147
      WBVar00832915
      WBVar02146756
      WBVar00832916
      WBVar01446127
      WBVar00298424
      WBVar01446128
      WBVar01446130
      WBVar01446132
      WBVar01566650
      WBVar01566651
      WBVar01566652
      WBVar01566653
      WBVar01566654
      WBVar01566655
      WBVar01566656
      WBVar00057125
      WBVar01837667
      WBVar00269789
      WBVar01656816
      WBVar00399582
      WBVar01656817
      WBVar00399583
      WBVar00399584
      WBVar00399585
      WBVar00399586
      WBVar00399587
    Strain: WBStrain00003713
      WBStrain00031470
      WBStrain00022222
    RNASeq_FPKM (74)
    GO_annotation (37)
    Ortholog (32)
    Paralog (20)
    Structured_description: Concise_description: gar-2 encodes a novel, seven transmembrane-domain G protein-coupled acetylcholine receptor (AChR); when expressed in Xenopus oocytes treated with acetylcholine, GAR-2 is able to activate a mammalian G protein-activated inwardly rectifying K+ (GIRK1) channel, but not other channels, suggesting that GAR-2 couples to G proteins of the Gi family; pharmacological analyses indicate, however, that GAR-2 exhibits properties distinct from mammalian muscarinic AChRs; gar-2 is expressed from mid-embryogenesis through adulthood with expression seen in ciliated head neurons, ventral cord neurons, and the HSN (hermaphrodite-specific neuron). Paper_evidence: WBPaper00004388
          Curator_confirmed: WBPerson1843
          Date_last_updated: 02 Nov 2006 00:00:00
      Automated_description: Enables G protein-coupled acetylcholine receptor activity. Involved in G protein-coupled receptor signaling pathway; negative regulation of cholinergic synaptic transmission; and response to xenobiotic stimulus. Located in axon. Expressed in neurons. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F47D12.1a
      F47D12.1b
      F47D12.1c
      F47D12.1d
      F47D12.1e
    Corresponding_CDS_history: F47D12.1c:wp275
    Corresponding_transcript: F47D12.1a.1
      F47D12.1b.1
      F47D12.1c.1
      F47D12.1d.1
      F47D12.1e.1
    Other_sequence: JI221387.1
      Dviv_isotig26799
      GO251308.1
      JI465005.1
      CBC06005_1
      FK808445.1
    Associated_feature (15)
  Experimental_info: RNAi_result (11)
    Expr_pattern: Chronogram723
      Expr1114
      Expr8178
      Expr8179
      Expr10067
      Expr1025714
      Expr1030913
      Expr1151485
      Expr2011945
      Expr2030182
    Drives_construct: WBCnstr00004148
      WBCnstr00009595
      WBCnstr00009870
      WBCnstr00010085
      WBCnstr00013162
      WBCnstr00015039
      WBCnstr00036893
    Construct_product: WBCnstr00001343
      WBCnstr00036893
    Microarray_results (49)
    Expression_cluster (178)
    Interaction: WBInteraction000126687
      WBInteraction000126688
      WBInteraction000177996
      WBInteraction000316805
      WBInteraction000446248
  Map_info: Map: III Position: -1.39824 Error: 0.002289
    Positive: Positive_clone: F47D12 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4334
        4407
    Pseudo_map_position
  Reference (31)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
    [140610 pad] Gene was missing Acquires_merge Event history data so inferred from Acquires_merge tag.
  Method: Gene