WormBase Tree Display for Gene: WBGene00001555
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| WBGene00001555 | SMap | S_parent | Sequence | T04D3 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | gcy-35 | Person_evidence | WBPerson655 | |||||
| Sequence_name | T04D3.4 | ||||||||
| Molecular_name | T04D3.4a | ||||||||
| T04D3.4a.1 | |||||||||
| CE34497 | |||||||||
| T04D3.4b | |||||||||
| CE46771 | |||||||||
| T04D3.4c | |||||||||
| CE46565 | |||||||||
| T04D3.4b.1 | |||||||||
| T04D3.4c.1 | |||||||||
| Other_name | CeGC1 | Paper_evidence | WBPaper00003629 | ||||||
| CELE_T04D3.4 | Accession_evidence | NDB | BX284601 | ||||||
| Public_name | gcy-35 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:24 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | gcy | ||||||||
| Allele (189) | |||||||||
| Strain | WBStrain00005284 | ||||||||
| WBStrain00040838 | |||||||||
| WBStrain00040844 | |||||||||
| WBStrain00031618 | |||||||||
| WBStrain00000304 | |||||||||
| WBStrain00005280 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (35) | |||||||||
| Ortholog (46) | |||||||||
| Paralog (36) | |||||||||
| Structured_description | Concise_description | gcy-35 encodes a soluble guanylyl cyclase; GCY-35 activity is required for regulation of aggregation, aerotaxis, aerokinesis, gustatory plasticity, and innate immunity; GCY-35 activity is also required in the URX sensory neurons to sense increases in O2 levels and effect corresponding behavioral changes; gcy-35::gfp reporter fusions are expressed in a number of neurons, including the AQR, PQR, and URX sensory neurons, the SDQL/R and BDU interneurons, the AVM and PVM mechanosensory neurons, the cholinergic ALN and PLN neurons, the excretory cell, and in pharyngeal and body wall muscles; gcy-35 expression in the URX neuron is positively regulated by the AHR-1 transcription complex; the heme-binding domain of GCY-35 binds molecular oxygen as well as NO and CO. | Paper_evidence | WBPaper00003992 | |||||
| WBPaper00024211 | |||||||||
| WBPaper00024217 | |||||||||
| WBPaper00027029 | |||||||||
| WBPaper00027202 | |||||||||
| WBPaper00028350 | |||||||||
| WBPaper00028424 | |||||||||
| WBPaper00032196 | |||||||||
| WBPaper00033008 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 24 Aug 2011 00:00:00 | ||||||||
| Automated_description | Enables carbon monoxide binding activity; nitric oxide binding activity; and oxygen sensor activity. Involved in several processes, including aerotaxis; cGMP-mediated signaling; and response to hyperoxia. Located in dendrite and neuronal cell body. Expressed in body wall musculature and pharyngeal muscle cell. Is an ortholog of human GUCY1B2 (guanylate cyclase 1 soluble subunit beta 2 (pseudogene)). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | T04D3.4a | |||||||
| T04D3.4b | |||||||||
| T04D3.4c | |||||||||
| Corresponding_CDS_history | T04D3.4:wp104 | ||||||||
| Corresponding_transcript | T04D3.4a.1 | ||||||||
| T04D3.4b.1 | |||||||||
| T04D3.4c.1 | |||||||||
| Other_sequence | Dviv_isotig23790 | ||||||||
| BXC01727_1 | |||||||||
| HBC26375_1 | |||||||||
| EX912238.1 | |||||||||
| JK314899.1 | |||||||||
| DW718336.1 | |||||||||
| Associated_feature (14) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00062075 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00035139 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00052391 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00000597 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00022435 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern (11) | |||||||||
| Drives_construct | WBCnstr00000627 | ||||||||
| WBCnstr00000629 | |||||||||
| WBCnstr00001835 | |||||||||
| WBCnstr00011061 | |||||||||
| WBCnstr00011066 | |||||||||
| WBCnstr00036865 | |||||||||
| Construct_product | WBCnstr00020209 | ||||||||
| WBCnstr00036865 | |||||||||
| WBCnstr00039997 | |||||||||
| WBCnstr00041898 | |||||||||
| Antibody | WBAntibody00001649 | ||||||||
| Microarray_results (22) | |||||||||
| Expression_cluster (119) | |||||||||
| Interaction (49) | |||||||||
| Anatomy_function | WBbtf0009 | ||||||||
| WBbtf0343 | |||||||||
| WBbtf0344 | |||||||||
| WBProcess | WBbiopr:00000039 | ||||||||
| WBbiopr:00000054 | |||||||||
| WBbiopr:00000063 | |||||||||
| Map_info | Map | I | Position | 17.684 | Error | 0.174053 | |||
| Positive | Positive_clone | T04D3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4680 | |||||||
| Pseudo_map_position | |||||||||
| Reference (59) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
