| WBGene00001683 | SMap | S_parent | Sequence | T09F3 |
|---|
| Identity | Version | 1 |
| | Name | CGC_name | gpd-1 | Person_evidence | WBPerson1051 |
| | | Sequence_name | T09F3.3 |
| | | Molecular_name | T09F3.3 |
| | | | T09F3.3.1 |
| | | | CE02343 |
| | | Other_name | CELE_T09F3.3 | Accession_evidence | NDB | BX284602 |
| | | Public_name | gpd-1 |
| | DB_info | Database (11) |
| | Species | Caenorhabditis elegans |
| | History | Version_change | 1 | 07 Apr 2004 11:29:25 | WBPerson1971 | Event | Imported | Initial conversion from geneace |
| | Status | Live |
| Gene_info | Biotype | SO:0001217 |
| | Gene_class | gpd |
| | Allele (23) |
| | Legacy_information | [C.elegansII] NMK. Encodes glyceraldehyde-3-phosphate-dehydrogenase, minor isozyme (GAPDHase-1), ubiquitous, predominant expression in embryo; sequence closest to gpd-4. [Barrios et al. 1989; HH] |
| | RNASeq_FPKM (74) |
| | GO_annotation (14) |
| | Contained_in_operon | CEOP2484 |
| | Ortholog (59) |
| | Paralog | WBGene00001686 | Caenorhabditis elegans | From_analysis | TreeFam |
| | | | | | Inparanoid_8 |
| | | | | | Panther |
| | | | | | WormBase-Compara |
| | | WBGene00001685 | Caenorhabditis elegans | From_analysis | Inparanoid_8 |
| | | | | | Panther |
| | | | | | WormBase-Compara |
| | | WBGene00001684 | Caenorhabditis elegans | From_analysis | Inparanoid_8 |
| | | | | | Panther |
| | | | | | WormBase-Compara |
| | Structured_description | Concise_description | gpd-1 encodes one of four C. elegans glyceraldehyde-3-phosphate dehydrogenases (GAPDHs); by homology, GPD-1 is predicted to reversibly catalyze the oxidation and phosphorylation of glyceraldehyde-3-phosphate to 1,3-diphosphoglycerate during glycolysis; GPD-1 is required for embryogenesis, normal body morphology, and gonad development; in C. elegans, GPD-1 and GPD-4 constitute the minor GAPDH isoenzymes and are expressed primarily in embryos, in all cell types. | Paper_evidence | WBPaper00000730 |
| | | | | | WBPaper00001143 |
| | | | | Curator_confirmed | WBPerson1843 |
| | | | | Date_last_updated | 17 Jun 2004 00:00:00 |
| | | Automated_description | Predicted to enable glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. Predicted to be involved in glycolytic process. Predicted to be located in cytosol. Expressed in germ line. Human ortholog(s) of this gene implicated in Alzheimer's disease and lymphangioleiomyomatosis. Is an ortholog of human GAPDH (glyceraldehyde-3-phosphate dehydrogenase). | Paper_evidence | WBPaper00065943 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | | WBPerson37462 |
| | | | | Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase |
| | | | | Date_last_updated | 29 Nov 2023 00:00:00 |
| Disease_info | Potential_model | DOID:10652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4141) |
| | | DOID:3319 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4141) |
| Molecular_info | Corresponding_CDS | T09F3.3 |
| | Corresponding_transcript | T09F3.3.1 |
| | Other_sequence (202) |
| | Associated_feature | WBsf1013017 |
| | | WBsf222004 |
| Experimental_info | RNAi_result | WBRNAi00018506 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00052969 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00008168 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00008043 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00114592 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00046227 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00014257 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00115891 | Inferred_automatically | RNAi_primary |
| | Expr_pattern | Expr776 |
| | | Expr4125 |
| | | Expr1031003 |
| | | Expr1156572 |
| | | Expr2012205 |
| | | Expr2030441 |
| | Drives_construct | WBCnstr00036773 |
| | Construct_product | WBCnstr00036773 |
| | Microarray_results | SMD_T09F3.3 |
| | | A_12_P101710 |
| | | GPL19516_CGZ0034430 |
| | | GPL19516_CGZ0034431 |
| | | GPL21109_T09F3.3.1 |
| | | GPL3518_CE02343 |
| | | GPL8304_CE_WBGene00001683_A |
| | | GPL8304_CE_WBGene00001683_B |
| | Expression_cluster | WBPaper00026640:Development_Group_II |
| | | WBPaper00028451:Oogenic_protein |
| | | WBPaper00031040:TGF-beta_adult_downregulated |
| | | WBPaper00032425:up_in_lin-35 |
| | | WBPaper00033208:STI-1_interacting |
| | | WBPaper00035963:S.aureus_8h_upregulated |
| | | WBPaper00035963:S.aureus_24h_downregulated |
| | | WBPaper00037047:aging_accelerated_insoluble_protein |
| | | WBPaper00037047:insoluble_protein |
| | | WBPaper00037086:biotin_regulated |
| | | WBPaper00038289:oocyte_protein |
| | | WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq |
| | | WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq |
| | | WBPaper00040221:DAF-12_target_ALF4 |
| | | WBPaper00041072:UTX-1_interacting_protein |
| | | WBPaper00041954:ethanol_upregulated |
| | | WBPaper00044426:rotenone_24h_upregulated |
| | | WBPaper00044501:gld-1_let-7_regulated |
| | | WBPaper00044656:tatn-1(qd182)_downregulated |
| | | WBPaper00044736:rising_dev_expression |
| | | WBPaper00044746:aging_upregulated_Day5 |
| | | WBPaper00044746:aging_upregulated_HeatShock |
| | | WBPaper00044786:emr-1(gk119)_downregulated |
| | | WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_downregulated |
| | | WBPaper00045316:prg-1_upregulated_L2 |
| | | WBPaper00045420:fertilization_downregulated_protein |
| | | WBPaper00045420:fertilization_downregulated_transcript |
| | | WBPaper00045521:Oogenic |
| | | WBPaper00045571:germline-ablation_downregulated |
| | | WBPaper00045774:clk-1_upregulated |
| | | WBPaper00046012:tdp-1(ok803)_downregulated |
| | | WBPaper00046337:polysomal_daf-2_vs_daf-2;daf-16_upregulated |
| | | WBPaper00046446:rapid-synthesized_YoungAdult |
| | | WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h |
| | | WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h |
| | | WBPaper00046509:lin-35(n745)_upregulated |
| | | WBPaper00048611:MnCl2_downregulated |
| | | WBPaper00048910:mRNA-interacting_protein |
| | | WBPaper00048923:Aging_regulated |
| | | WBPaper00048971:daf-16(mgDf50)_downregulated_L1 |
| | | WBPaper00048988:neuron_expressed |
| | | WBPaper00049545:jmjd-3.1(+)_downregulated |
| | | WBPaper00049920:Glucose-Diet_downregulated_N2 |
| | | WBPaper00049942:hsf-1(RNAi)_upregulated |
| | | WBPaper00050182:lmn-1(L535P)_downregulated |
| | | WBPaper00050488:adult_vs_dauer_regulated_N2_20C |
| | | WBPaper00050522:mafr-1(tm6082)_downregulated |
| | | WBPaper00050636:aging_regulated_insoluble_protein |
| | | WBPaper00050686:glp-1(e2141)_downregulated |
| | | WBPaper00050698:DEP-1_interacting |
| | | WBPaper00050859:downregulated_glh-1(gk100)_vs_control_day1-adult |
| | | WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult |
| | | WBPaper00050859:downregulated_P-granule(-)GFP(-)_vs_control_day2-adult |
| | | WBPaper00050990:GABAergic-neuron_expressed |
| | | WBPaper00050990:hypodermis_expressed |
| | | WBPaper00050990:intestine_expressed |
| | | WBPaper00050990:NMDA-neuron_expressed |
| | | WBPaper00051039:germline_enriched |
| | | WBPaper00051245:body-wall-muscle_cytoplasm_expressed |
| | | WBPaper00051245:body-wall-muscle_nucleus_expressed |
| | | WBPaper00051245:epidermis_cytoplasm_expressed |
| | | WBPaper00051245:epidermis_nucleus_expressed |
| | | WBPaper00051245:intestine_cytoplasm_expressed |
| | | WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed |
| | | WBPaper00051310:LIN-41_interacting |
| | | WBPaper00051558:fog-2(q71)_regulated |
| | | WBPaper00052884:emb-4(hc60)_downregulated |
| | | WBPaper00053184:sma-2(rax5)_downregulated |
| | | WBPaper00053184:sma-4(rax3)_downregulated |
| | | WBPaper00053295:lin-22(ot269)_downregulated |
| | | WBPaper00053302:alovudine_24h_regulated |
| | | WBPaper00053302:stavudine_24h_regulated |
| | | WBPaper00053302:zidovudine_24h_regulated |
| | | WBPaper00053302:zidovudine_72h_regulated |
| | | WBPaper00053321:PGCs_enriched_NuGen |
| | | WBPaper00053388:dauer_regulated_Cluster2 |
| | | WBPaper00053599:mitosis_vs_meiosis_downregulated |
| | | WBPaper00053599:oocyte_vs_mitosis_downregulated |
| | | WBPaper00053713:Starvation-induced_postdauer_vs_control_downregulated |
| | | WBPaper00053810:nuo-6(qm200)_downregulated |
| | | WBPaper00053814:25C_downregulated_OP50 |
| | | WBPaper00053814:25C_downregulated_PY79 |
| | | WBPaper00054189:P.aeruginosa_regulated_protein |
| | | WBPaper00055049:S.gordonii_downregulated |
| | | WBPaper00055103:thoc-5(wy822)_downregulated |
| | | WBPaper00055354:Rapamycin-Rifampicin_downregulated |
| | | WBPaper00055354:Rifampicin_downregulated |
| | | WBPaper00055648:germline_expressed |
| | | WBPaper00055804:FBF-1-FBF-2-associated_oogenic-enriched |
| | | WBPaper00055862:antimycin_damt-1(gk961032)_regulated |
| | | WBPaper00055971:nhl-2(ok818)_25C_upregulated |
| | | WBPaper00056034:pals-22(jy3)_downregulated |
| | | WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047) |
| | | WBPaper00056139:soil-microbiota_downregulated |
| | | WBPaper00056275:P.aeruginosa_downregulated |
| | | WBPaper00056275:P.aeruginosa_upregulated |
| | | WBPaper00056275:P.aeruginosa_upregulated_atf-7(qd22qd130)_dependent |
| | | WBPaper00056290:hsp-6(mg585)_downregulated |
| | | WBPaper00056293:rpl-5(0)-rpl-33(0)_upregulated |
| | | WBPaper00056443:sek-1(km4)_downregulated |
| | | WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated |
| | | WBPaper00056471:S.aureus-4h_upregulated_N2 |
| | | WBPaper00056900:PID-3_interacting |
| | | WBPaper00056997:nmad-1(ok3133)_downregulated_germline_25C |
| | | WBPaper00057041:spc-1(cas971)_upregulated |
| | | WBPaper00057041:unc-70(cas983)_upregulated |
| | | WBPaper00057288:iff-1(RNAi)_downregulated_transcript |
| | | WBPaper00058598:mex-3(eu149)_downregulated |
| | | WBPaper00058598:sin-3(tm1276)_upregulated |
| | | WBPaper00058691:cfp-1(tm6369)_upregulated |
| | | WBPaper00058886:anp-1(ok608)_downregulated |
| | | WBPaper00058955:heatshock_upregulated_CE |
| | | WBPaper00058958:100mGy-irradiation-72h_upregulated |
| | | WBPaper00059027:neuron-synapses_enriched |
| | | WBPaper00059328:mrps-5(RNAi)_downregulated_protein |
| | | WBPaper00059605:MUT-16_interacting |
| | | WBPaper00059664:srbc-48(ac23)_downregulated |
| | | WBPaper00059739:hira-1(gk835598)_upregulated_L1 |
| | | WBPaper00059739:hira-1(gk835598)_upregulated_L4 |
| | | WBPaper00060014:set-2(tm1630)_upregulated |
| | | WBPaper00060084:DVE-1_interacting_protein_cco-1(RNAi) |
| | | WBPaper00060100:SiNP_upregulated_mRNA |
| | | WBPaper00060661:sensory-neuron_depleted |
| | | WBPaper00060683:hlh-11(ko1)_downregulated |
| | | WBPaper00060811:L1_vs_adult_downregulated_neural |
| | | WBPaper00060871:M.humicola-infection_48h_regulated |
| | | WBPaper00060909:atfs-1(cmh15)_upregulated |
| | | WBPaper00060909:atfs-1(et18)_upregulated |
| | | WBPaper00061007:HB101_downregulated |
| | | WBPaper00061007:S.aquatilis_downregulated |
| | | WBPaper00061045:Y56A3A.22(cck200)_downregulated |
| | | WBPaper00061203:sin-3(tm1276)_downregulated |
| | | WBPaper00061203:spr-1(ok2144)_downregulated |
| | | WBPaper00061274:hypergravity_15xg_upregulated |
| | | WBPaper00061340:Germline |
| | | WBPaper00061341:28C_24h_downregulated |
| | | WBPaper00061377:MYRF-1_interacting |
| | | WBPaper00061478:SUMO-conjugated_protein |
| | | WBPaper00061527:let-99_22121-B0238.9_11154 |
| | | WBPaper00061527:puf-3-oma-2_18268 |
| | | WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR |
| | | WBPaper00062002:Day4-adult_secretome |
| | | WBPaper00062056:lin-15B(n744)_upregulated |
| | | WBPaper00062056:lin-35(n745)_upregulated |
| | | WBPaper00062143:PQN-59_interacting |
| | | WBPaper00062159:hda-2(ok1479)_downregulated |
| | | WBPaper00062193:skn-1(RNAi)_upregulated |
| | | WBPaper00062325:muscle_enriched_coding-RNA |
| | | WBPaper00062446:nhr-8(hd117)_downregulated |
| | | WBPaper00062456:doxycycline_downregulated_CB4856_protein |
| | | WBPaper00062456:doxycycline_downregulated_N2_protein |
| | | WBPaper00062554:MAGU-2_interacting |
| | | WBPaper00062669:extracellular-vesicle_protein |
| | | WBPaper00063976:micu-1(bon20)_downregulated |
| | | WBPaper00064005:starvation_downregulated_aptf-1(gk794)_mRNA |
| | | WBPaper00064005:starvation_downregulated_N2_mRNA |
| | | WBPaper00064071:NHR-49_interacting |
| | | WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141) |
| | | WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20) |
| | | WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141) |
| | | WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20) |
| | | WBPaper00064163:ZNFX-1_interacting_young-adult |
| | | WBPaper00064201:SNA-1_interacting |
| | | WBPaper00064201:SNA-3_interacting |
| | | WBPaper00064229:B.thuringiensis-Cry5Ba_downregulated |
| | | WBPaper00064257:UNG-1_interacting |
| | | WBPaper00064315:mes-3(bn199)_downregulated_PGCs |
| | | WBPaper00064315:mrg-1(qa6200)_downregulated_PGCs |
| | | WBPaper00064403:Heat-killed-E.Coli_upregulated |
| | | WBPaper00064716:paraquat_upregulated |
| | | WBPaper00064871:hypoxia_upregulated_F2 |
| | | WBPaper00064992:Capsaicin_downregulated |
| | | WBPaper00064992:Eugenol_downregulated |
| | | WBPaper00065096:25C_vs_20C_upregulated |
| | | WBPaper00065096:Day10_vs_Day1_upregulated |
| | | WBPaper00065120:body-muscle-transcriptome |
| | | WBPaper00065149:lin-52(n771)_upregulated |
| | | WBPaper00065373:Cisplatin_upregulated_WT |
| | | WBPaper00065373:sek-1(km4)_upregulated_cisplatin |
| | | WBPaper00065749:Heat-Shock_upregulated_endu-2(tm4977) |
| | | WBPaper00065749:Heat-Shock_upregulated_N2 |
| | | WBPaper00065926:pgph-2(overepxreesion)_upregulated |
| | | WBPaper00065975:P-body_vs_oocyte_depleted |
| | | WBPaper00065975:P-body_vs_WholeAnimal_depleted |
| | | WBPaper00065984:pals-17(syb3980)_upregulated |
| | | WBPaper00065993:glp-1(e2141)_downregulated |
| | | WBPaper00066085:hda-3(ok1991)_downregulated |
| | | WBPaper00066110:tetraploid_vs_diploid_downregulated |
| | | WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14 |
| | | cgc4489_group_9 |
| | | WBPaper00026929:sir-2.1_overexpression_regulated |
| | | WBPaper00027758:Group_I |
| | | WBPaper00036130:mir-243_down_regulated |
| | | WBPaper00041606:CE_B.thuringiensis-DB27_regulated |
| | | WBPaper00041606:CE_S.marcescens_regulated |
| | | WBPaper00041606:CE_X.nematophila_regulated |
| | | [cgc6390]:Cluster_E |
| | | [cgc6390]:oogenesis-enriched |
| | Interaction (162) |
| Map_info | Map | II | Position | 2.55928 | Error | 0.007034 |
| | Positive | Positive_clone | HH#7B |
| | | | T09F3 | Inferred_automatically | From sequence, transcript, pseudogene data |
| | Pseudo_map_position |
| Reference (25) |
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission |
| Method | Gene |
