WormBase Tree Display for Gene: WBGene00001683

WBGene00001683 SMap: S_parent: Sequence: T09F3
  Identity: Version: 1
    Name: CGC_name: gpd-1 Person_evidence: WBPerson1051
      Sequence_name: T09F3.3
      Molecular_name: T09F3.3
        T09F3.3.1
        CE02343
      Other_name: CELE_T09F3.3 Accession_evidence: NDB BX284602
      Public_name: gpd-1
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:25 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: gpd
    Allele (23)
    Legacy_information: [C.elegansII] NMK. Encodes glyceraldehyde-3-phosphate-dehydrogenase, minor isozyme (GAPDHase-1), ubiquitous, predominant expression in embryo; sequence closest to gpd-4. [Barrios et al. 1989; HH]
    RNASeq_FPKM (74)
    GO_annotation (14)
    Contained_in_operon: CEOP2484
    Ortholog (59)
    Paralog: WBGene00001686 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00001685 Caenorhabditis elegans From_analysis: Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00001684 Caenorhabditis elegans From_analysis: Inparanoid_8
            Panther
            WormBase-Compara
    Structured_description: Concise_description: gpd-1 encodes one of four C. elegans glyceraldehyde-3-phosphate dehydrogenases (GAPDHs); by homology, GPD-1 is predicted to reversibly catalyze the oxidation and phosphorylation of glyceraldehyde-3-phosphate to 1,3-diphosphoglycerate during glycolysis; GPD-1 is required for embryogenesis, normal body morphology, and gonad development; in C. elegans, GPD-1 and GPD-4 constitute the minor GAPDH isoenzymes and are expressed primarily in embryos, in all cell types. Paper_evidence: WBPaper00000730
            WBPaper00001143
          Curator_confirmed: WBPerson1843
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. Predicted to be involved in glycolytic process. Predicted to be located in cytosol. Expressed in germ line. Human ortholog(s) of this gene implicated in Alzheimer's disease and lymphangioleiomyomatosis. Is an ortholog of human GAPDH (glyceraldehyde-3-phosphate dehydrogenase). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:10652 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4141)
      DOID:3319 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4141)
  Molecular_info: Corresponding_CDS: T09F3.3
    Corresponding_transcript: T09F3.3.1
    Other_sequence (202)
    Associated_feature: WBsf1013017
      WBsf222004
  Experimental_info: RNAi_result: WBRNAi00018506 Inferred_automatically: RNAi_primary
      WBRNAi00052969 Inferred_automatically: RNAi_primary
      WBRNAi00008168 Inferred_automatically: RNAi_primary
      WBRNAi00008043 Inferred_automatically: RNAi_primary
      WBRNAi00114592 Inferred_automatically: RNAi_primary
      WBRNAi00046227 Inferred_automatically: RNAi_primary
      WBRNAi00014257 Inferred_automatically: RNAi_primary
      WBRNAi00115891 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr776
      Expr4125
      Expr1031003
      Expr1156572
      Expr2012205
      Expr2030441
    Drives_construct: WBCnstr00036773
    Construct_product: WBCnstr00036773
    Microarray_results: SMD_T09F3.3
      A_12_P101710
      GPL19516_CGZ0034430
      GPL19516_CGZ0034431
      GPL21109_T09F3.3.1
      GPL3518_CE02343
      GPL8304_CE_WBGene00001683_A
      GPL8304_CE_WBGene00001683_B
    Expression_cluster (198)
    Interaction: WBInteraction000036340
      WBInteraction000044291
      WBInteraction000044292
      WBInteraction000044293
      WBInteraction000045992
      WBInteraction000047359
      WBInteraction000047360
      WBInteraction000102281
      WBInteraction000102289
      WBInteraction000102691
      WBInteraction000102883
      WBInteraction000105141
      WBInteraction000105142
      WBInteraction000112579
      WBInteraction000135543
      WBInteraction000135557
      WBInteraction000135565
      WBInteraction000135597
      WBInteraction000137980
      WBInteraction000140827
      WBInteraction000140839
      WBInteraction000140859
      WBInteraction000140860
      WBInteraction000140862
      WBInteraction000140864
      WBInteraction000140871
      WBInteraction000140887
      WBInteraction000140897
      WBInteraction000143152
      WBInteraction000145301
      WBInteraction000155185
      WBInteraction000156358
      WBInteraction000160381
      WBInteraction000160392
      WBInteraction000162887
      WBInteraction000162957
      WBInteraction000167376
      WBInteraction000167446
      WBInteraction000167862
      WBInteraction000167868
      WBInteraction000172125
      WBInteraction000172822
      WBInteraction000172830
      WBInteraction000172838
      WBInteraction000172846
      WBInteraction000175527
      WBInteraction000177124
      WBInteraction000177396
      WBInteraction000185148
      WBInteraction000191802
      WBInteraction000192893
      WBInteraction000193795
      WBInteraction000208284
      WBInteraction000210572
      WBInteraction000218989
      WBInteraction000222530
      WBInteraction000228957
      WBInteraction000229816
      WBInteraction000233092
      WBInteraction000240461
      WBInteraction000244678
      WBInteraction000246522
      WBInteraction000252325
      WBInteraction000252760
      WBInteraction000253931
      WBInteraction000253933
      WBInteraction000259287
      WBInteraction000259980
      WBInteraction000263325
      WBInteraction000264477
      WBInteraction000267121
      WBInteraction000267275
      WBInteraction000272802
      WBInteraction000273866
      WBInteraction000278843
      WBInteraction000279251
      WBInteraction000279391
      WBInteraction000285642
      WBInteraction000288368
      WBInteraction000292299
      WBInteraction000302542
      WBInteraction000310286
      WBInteraction000317929
      WBInteraction000322756
      WBInteraction000322757
      WBInteraction000322758
      WBInteraction000322759
      WBInteraction000330644
      WBInteraction000330870
      WBInteraction000339862
      WBInteraction000343406
      WBInteraction000346033
      WBInteraction000348592
      WBInteraction000352238
      WBInteraction000356400
      WBInteraction000359710
      WBInteraction000362726
      WBInteraction000362990
      WBInteraction000366445
      WBInteraction000366594
      WBInteraction000366811
      WBInteraction000367202
      WBInteraction000367879
      WBInteraction000367986
      WBInteraction000370166
      WBInteraction000370369
      WBInteraction000374059
      WBInteraction000375012
      WBInteraction000377027
      WBInteraction000377888
      WBInteraction000379807
      WBInteraction000382458
      WBInteraction000384958
      WBInteraction000391882
      WBInteraction000392413
      WBInteraction000397333
      WBInteraction000400466
      WBInteraction000401562
      WBInteraction000402567
      WBInteraction000405069
      WBInteraction000409872
      WBInteraction000416147
      WBInteraction000421448
      WBInteraction000437899
      WBInteraction000439690
      WBInteraction000439835
      WBInteraction000442736
      WBInteraction000446342
      WBInteraction000453705
      WBInteraction000454854
      WBInteraction000455699
      WBInteraction000456131
      WBInteraction000458035
      WBInteraction000458497
      WBInteraction000461289
      WBInteraction000463382
      WBInteraction000463408
      WBInteraction000464267
      WBInteraction000464728
      WBInteraction000465539
      WBInteraction000466549
      WBInteraction000466816
      WBInteraction000468684
      WBInteraction000468800
      WBInteraction000468878
      WBInteraction000469563
      WBInteraction000471611
      WBInteraction000473644
      WBInteraction000540301
      WBInteraction000549553
      WBInteraction000550360
      WBInteraction000562303
      WBInteraction000563334
      WBInteraction000566347
      WBInteraction000566626
      WBInteraction000569002
      WBInteraction000569622
      WBInteraction000570434
      WBInteraction000572376
      WBInteraction000573426
      WBInteraction000579362
      WBInteraction000580018
  Map_info: Map: II Position: 2.55928 Error: 0.007034
    Positive: Positive_clone: HH#7B
        T09F3 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (25)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene