WormBase Tree Display for Gene: WBGene00001683

WBGene00001683 SMap: S_parent: Sequence: T09F3
  Identity: Version: 1
    Name: CGC_name: gpd-1 Person_evidence: WBPerson1051
      Sequence_name: T09F3.3
      Molecular_name: T09F3.3
        T09F3.3.1
        CE02343
      Other_name: CELE_T09F3.3 Accession_evidence: NDB BX284602
      Public_name: gpd-1
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:25 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: gpd
    Allele (23)
    Legacy_information: [C.elegansII] NMK. Encodes glyceraldehyde-3-phosphate-dehydrogenase, minor isozyme (GAPDHase-1), ubiquitous, predominant expression in embryo; sequence closest to gpd-4. [Barrios et al. 1989; HH]
    RNASeq_FPKM (74)
    GO_annotation (14)
    Contained_in_operon: CEOP2484
    Ortholog: WBGene00024150 Caenorhabditis briggsae From_analysis: OrthoMCL
            WormBase-Compara
      WBGene00024712 Caenorhabditis briggsae From_analysis: OrthoMCL
            Inparanoid_8
            WormBase-Compara
      WBGene00123586 Caenorhabditis japonica From_analysis: TreeFam
            WormBase-Compara
      WBGene00057875 Caenorhabditis remanei From_analysis: TreeFam
            WormBase-Compara
      WBGene00148223 Caenorhabditis brenneri From_analysis: TreeFam
            WormBase-Compara
      WBGene00152202 Caenorhabditis brenneri From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00161625 Caenorhabditis brenneri From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00132155 Caenorhabditis japonica From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00057911 Caenorhabditis remanei From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00102337 Pristionchus pacificus From_analysis: Inparanoid_8
      WBGene00151788 Caenorhabditis brenneri From_analysis: WormBase-Compara
      WBGene00225232 Brugia malayi From_analysis: WormBase-Compara
      WBGene00225960 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g10866 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g8370 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g20867 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP26.g20872 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g4854 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g18397 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g18612 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g15562 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP39.g3668 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g13637 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      CSP40.g2807 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cnig_chr_V.g16739 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Cnig_chr_V.g16888 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold58.g348 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp11.Scaffold58.g354 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_02145.g25103 Caenorhabditis sinica From_analysis: WormBase-Compara
      Csp5_scaffold_04643.g33418 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_20376 Caenorhabditis latens From_analysis: WormBase-Compara
      FL83_23329 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_019405 Caenorhabditis remanei From_analysis: WormBase-Compara
      GCK72_019456 Caenorhabditis remanei From_analysis: WormBase-Compara
      Sp34_50010500 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrII_pilon.g5720 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00248297 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00248298 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00256803 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00263559 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00266672 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00292118 Trichuris muris From_analysis: WormBase-Compara
      SGD:S000003424 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      SGD:S000003588 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      SGD:S000003769 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      FB:FBgn0001092 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            PhylomeDB
            SonicParanoid
      FB:FBgn0034173 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Panther
            PhylomeDB
      ZFIN:ZDB-GENE-030115-1 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:4141 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      MGI:95640 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:3708786 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:3782011 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      RGD:2661 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1564958 Rattus norvegicus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      RGD:1566089 Rattus norvegicus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:7581466 Rattus norvegicus From_analysis: OMA
            OrthoFinder
            Panther
      RGD:11474079 Rattus norvegicus From_analysis: Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      RGD:11507219 Rattus norvegicus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:41326322 Rattus norvegicus From_analysis: OrthoFinder
            Panther
            PhylomeDB
    Paralog: WBGene00001686 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00001685 Caenorhabditis elegans From_analysis: Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00001684 Caenorhabditis elegans From_analysis: Inparanoid_8
            Panther
            WormBase-Compara
    Structured_description: Concise_description: gpd-1 encodes one of four C. elegans glyceraldehyde-3-phosphate dehydrogenases (GAPDHs); by homology, GPD-1 is predicted to reversibly catalyze the oxidation and phosphorylation of glyceraldehyde-3-phosphate to 1,3-diphosphoglycerate during glycolysis; GPD-1 is required for embryogenesis, normal body morphology, and gonad development; in C. elegans, GPD-1 and GPD-4 constitute the minor GAPDH isoenzymes and are expressed primarily in embryos, in all cell types. Paper_evidence: WBPaper00000730
            WBPaper00001143
          Curator_confirmed: WBPerson1843
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. Predicted to be involved in glycolytic process. Predicted to be located in cytosol. Expressed in germ line. Human ortholog(s) of this gene implicated in Alzheimer's disease and lymphangioleiomyomatosis. Is an ortholog of human GAPDH (glyceraldehyde-3-phosphate dehydrogenase). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:10652 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4141)
      DOID:3319 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4141)
  Molecular_info: Corresponding_CDS: T09F3.3
    Corresponding_transcript: T09F3.3.1
    Other_sequence (202)
    Associated_feature: WBsf1013017
      WBsf222004
  Experimental_info: RNAi_result: WBRNAi00018506 Inferred_automatically: RNAi_primary
      WBRNAi00052969 Inferred_automatically: RNAi_primary
      WBRNAi00008168 Inferred_automatically: RNAi_primary
      WBRNAi00008043 Inferred_automatically: RNAi_primary
      WBRNAi00114592 Inferred_automatically: RNAi_primary
      WBRNAi00046227 Inferred_automatically: RNAi_primary
      WBRNAi00014257 Inferred_automatically: RNAi_primary
      WBRNAi00115891 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr776
      Expr4125
      Expr1031003
      Expr1156572
      Expr2012205
      Expr2030441
    Drives_construct: WBCnstr00036773
    Construct_product: WBCnstr00036773
    Microarray_results: SMD_T09F3.3
      A_12_P101710
      GPL19516_CGZ0034430
      GPL19516_CGZ0034431
      GPL21109_T09F3.3.1
      GPL3518_CE02343
      GPL8304_CE_WBGene00001683_A
      GPL8304_CE_WBGene00001683_B
    Expression_cluster (198)
    Interaction (162)
  Map_info: Map: II Position: 2.55928 Error: 0.007034
    Positive: Positive_clone: HH#7B
        T09F3 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (25)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene