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WormBase Tree Display for Gene: WBGene00001683

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Name Class

WBGene00001683SMapS_parentSequenceT09F3
Identity (6)
Gene_infoBiotypeSO:0001217
Gene_classgpd
Allele (23)
Legacy_information[C.elegansII] NMK. Encodes glyceraldehyde-3-phosphate-dehydrogenase, minor isozyme (GAPDHase-1), ubiquitous, predominant expression in embryo; sequence closest to gpd-4. [Barrios et al. 1989; HH]
RNASeq_FPKM (74)
GO_annotation (14)
Contained_in_operonCEOP2484
Ortholog (59)
ParalogWBGene00001686Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00001685Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
WBGene00001684Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
Structured_descriptionConcise_descriptiongpd-1 encodes one of four C. elegans glyceraldehyde-3-phosphate dehydrogenases (GAPDHs); by homology, GPD-1 is predicted to reversibly catalyze the oxidation and phosphorylation of glyceraldehyde-3-phosphate to 1,3-diphosphoglycerate during glycolysis; GPD-1 is required for embryogenesis, normal body morphology, and gonad development; in C. elegans, GPD-1 and GPD-4 constitute the minor GAPDH isoenzymes and are expressed primarily in embryos, in all cell types.Paper_evidenceWBPaper00000730
WBPaper00001143
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. Predicted to be involved in glycolytic process. Predicted to be located in cytosol. Expressed in germ line. Human ortholog(s) of this gene implicated in Alzheimer's disease and lymphangioleiomyomatosis. Is an ortholog of human GAPDH (glyceraldehyde-3-phosphate dehydrogenase).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:10652Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4141)
DOID:3319Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4141)
Molecular_infoCorresponding_CDST09F3.3
Corresponding_transcriptT09F3.3.1
Other_sequenceES566695.1
ES564732.1
FG349761.1
FC809957.1
BF154330.1
GO252086.1
CK725785.1
EX545233.1
ES562454.1
PPC05786_1
AF452243.1
FG580758.1
ES413177.1
FG354261.1
FG347763.1
FC812186.1
BI773058.1
BE132463.1
GO239949.1
HG08176
BF023733.1
CK726316.1
BF064394.1
ES568299.1
ES563982.1
AE02289
EX501666.1
AF452245.1
FG586660.1
FG970826.1
FG355025.1
FC815377.1
ES563696.1
FG585678.1
FG586532.1
FG587511.1
ES565819.1
FG354813.1
GO240441.1
BF482036.1
AF452246.1
FC820061.1
PP01621
BI773210.1
FC812166.1
AF452244.1
GT570714.1
BMC11759_1
EX500727.1
EW742058.1
FG586972.1
FG580780.1
FG347998.1
CK855485.1
EU625274.1
MA01345
EX553067.1
ES562716.1
HG05456
EX539005.1
AS03429
BE132603.1
FG586787.1
FG351405.1
PT00188
FG355446.1
AF452242.1
MHC08362_1
FC816792.1
XI02391
CK855224.1
MA01802
BI773561.1
FC811286.1
TCC02387_1
FG352748.1
EX540010.1
AF004522.1
CK854850.1
FK670236.1
EX538616.1
WBC03265_1
EV853968.1
BI773569.1
FG354735.1
FC815322.1
BI772868.1
HGC07934_1
BI773562.1
AYC01711_1
CK725960.1
EX500751.1
OVC05704_1
BE132601.1
FG587744.1
Dviv_isotig19339
BF824678.1
FG586945.1
Acan_isotig03712
EX501476.1
FC811404.1
FG977751.1
AF452241.1
JI476940.1
GO239980.1
FG348971.1
AE01655
AW980281.1
EV851320.1
MAC00518_2
FG581151.1
CR06668
GP02246
AF452239.1
FC816927.1
FC817067.1
FG582886.1
FG974416.1
EX541858.1
EX550864.1
DVC00283_1
BI773151.1
EX546659.1
CK850384.1
AA294278.1
CK850569.1
ACC08395_2
CBC14518_1
WBC01365_1
FC817801.1
EX540003.1
BI773080.1
FG354737.1
FE910656.1
AF452240.1
BI772919.1
ZPC00237_1
FG586088.1
ASC01421_1
AS04177
BI773205.1
ASC06464_1
BE191706.1
FG584592.1
FG581797.1
FG588225.1
PTC01843_1
FG581411.1
AA625042.1
FG354858.1
ES565730.1
CK854847.1
MA00494
XIC01198_1
TSC04697_1
EX502396.1
AS04911
FG582672.1
MCC00737_1
PPC05473_1
EX502324.1
AS07990
MC00207
ES273507.1
TS01571
EV851460.1
CJC10218_1
FG619375.1
EX544756.1
FG588439.1
GT570700.1
FC811521.1
HC01341
FG351114.1
ES561635.1
FC545943.1
EX537837.1
TSC00908_1
FG354170.1
TX00129
JI471378.1
FG355506.1
FG586246.1
FG354758.1
CGC00397_1
ES565429.1
SRC02646_2
FG586406.1
HG11001
EX541959.1
FG588113.1
AA625048.1
TSC06174_1
TS01226
GE639136.1
FG354195.1
ES568408.1
EV850811.1
ACC08395_1
Acan_isotig03711
XI00630
TS03451
Associated_featureWBsf1013017
WBsf222004
Experimental_info (7)
Map_infoMapIIPosition2.55928Error0.007034
PositivePositive_cloneHH#7B
T09F3Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (25)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene