WormBase Tree Display for Gene: WBGene00001974
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| WBGene00001974 | Evidence | CGC_data_submission | |||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | T20B12 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | hmg-4 | |||||||
| Sequence_name | T20B12.8 | ||||||||
| Molecular_name | T20B12.8 | ||||||||
| T20B12.8.1 | |||||||||
| CE01414 | |||||||||
| Other_name | CELE_T20B12.8 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | hmg-4 | ||||||||
| DB_info | Database | AceView | gene | 3I470 | |||||
| WormQTL | gene | WBGene00001974 | |||||||
| WormFlux | gene | WBGene00001974 | |||||||
| NDB | locus_tag | CELE_T20B12.8 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00001974|UniProtKB=P41848 | |||||||
| family | PTHR45849 | ||||||||
| NCBI | gene | 176052 | |||||||
| RefSeq | protein | NM_066232.7 | |||||||
| SwissProt | UniProtAcc | P41848 | |||||||
| TREEFAM | TREEFAM_ID | TF315228 | |||||||
| UniProt_GCRP | UniProtAcc | P41848 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | hmg | ||||||||
| Allele (28) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (17) | |||||||||
| Contained_in_operon | CEOP3432 | ||||||||
| Ortholog (40) | |||||||||
| Paralog | WBGene00001973 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00001972 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00008081 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00012209 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00022182 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | hmg-4 encodes a protein with strong similarity to the highly conserved high mobility group protein SSRP1 (structure-specific DNA recognition protein); by homology, HMG-4 is predicted to be a member of the FACT (facilitates chromatin transcription) complex that functions as a transcription elongation factor; RNAi experiments indicate that hmg-4 is required for locomotion and larval development, and required redundantly with hmg-3, its paralog, for embryonic development. | Paper_evidence | WBPaper00018389 | |||||
| WBPaper00018725 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable histone binding activity and nucleosome binding activity. Involved in regulation of embryonic development. Located in nucleus. Expressed in several structures, including coelomocyte; head muscle; neurons; somatic cell; and somatic nervous system. Is an ortholog of human SSRP1 (structure specific recognition protein 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | T20B12.8 | |||||||
| Corresponding_transcript | T20B12.8.1 | ||||||||
| Other_sequence (65) | |||||||||
| Associated_feature | WBsf651203 | ||||||||
| WBsf655453 | |||||||||
| WBsf667074 | |||||||||
| WBsf667075 | |||||||||
| WBsf667076 | |||||||||
| WBsf978766 | |||||||||
| WBsf226976 | |||||||||
| WBsf226977 | |||||||||
| Transcription_factor | WBTranscriptionFactor000348 | ||||||||
| Experimental_info | RNAi_result (41) | ||||||||
| Expr_pattern | Expr7669 | ||||||||
| Expr13852 | |||||||||
| Expr1016203 | |||||||||
| Expr1031144 | |||||||||
| Expr1157147 | |||||||||
| Expr2012521 | |||||||||
| Expr2030760 | |||||||||
| Drives_construct | WBCnstr00012814 | ||||||||
| WBCnstr00036549 | |||||||||
| Construct_product | WBCnstr00016596 | ||||||||
| WBCnstr00036549 | |||||||||
| WBCnstr00038803 | |||||||||
| Regulate_expr_cluster | WBPaper00055013:hmg-4(RNAi)_downregulated | ||||||||
| WBPaper00055013:hmg-4(RNAi)_upregulated | |||||||||
| WBPaper00055013:HMG-4_interacting_protein | |||||||||
| Microarray_results (25) | |||||||||
| Expression_cluster (140) | |||||||||
| Interaction (330) | |||||||||
| Map_info | Map | III | Position | -0.742919 | Error | 0.002225 | |||
| Positive | Positive_clone | T20B12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 5263 | |||||||
| 4724 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (13) | |||||||||
| Remark | Sequence connection from [Sugimoto A] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
