WormBase Tree Display for Gene: WBGene00002150
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| WBGene00002150 | SMap | S_parent | Sequence | M02A10 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | irk-2 | Person_evidence | WBPerson655 | |||||
| Sequence_name | M02A10.2 | ||||||||
| Molecular_name (19) | |||||||||
| Other_name | CELE_M02A10.2 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | irk-2 | ||||||||
| DB_info | Database | AceView | gene | XB322 | |||||
| WormQTL | gene | WBGene00002150 | |||||||
| WormFlux | gene | WBGene00002150 | |||||||
| NDB | locus_tag | CELE_M02A10.2 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00002150|UniProtKB=A0A1C3NSN6 | |||||||
| family | PTHR11767 | ||||||||
| NCBI | gene | 191695 | |||||||
| RefSeq | protein | NM_001330888.3 | |||||||
| NM_001270048.3 | |||||||||
| NM_001380895.1 | |||||||||
| NM_001380896.1 | |||||||||
| NM_001307921.4 | |||||||||
| NM_001270047.4 | |||||||||
| TrEMBL | UniProtAcc | A0A1C3NSN6 | |||||||
| H2KYE6 | |||||||||
| D3YT08 | |||||||||
| A0A1C3NSR3 | |||||||||
| U4PSB4 | |||||||||
| U4PN13 | |||||||||
| UniProt_GCRP | UniProtAcc | A0A1C3NSN6 | |||||||
| OMIM | gene | 600681 | |||||||
| 600734 | |||||||||
| 600937 | |||||||||
| 613236 | |||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | irk | ||||||||
| Allele (166) | |||||||||
| Legacy_information | [Thomas JH] irk for Inward Rectifying potassium (K) channel family. Predicted gene M02A10.2 | ||||||||
| Strain | WBStrain00037929 | ||||||||
| WBStrain00039809 | |||||||||
| WBStrain00047557 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (14) | |||||||||
| Ortholog (82) | |||||||||
| Paralog | WBGene00002149 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00002151 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | irk-2 encodes an inwardly rectifying potassium channel based on sequence homology to the the human potassium channel genes KCNJ1/KCNJ2. | Paper_evidence | WBPaper00006402 | |||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable inward rectifier potassium channel activity. Predicted to be involved in potassium ion import across plasma membrane and regulation of monoatomic ion transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of monoatomic ion channel complex. Expressed in intestine; pharyngeal-intestinal valve cell; spermatheca; and uterus. Human ortholog(s) of this gene implicated in several diseases, including glucose metabolism disease (multiple); heart conduction disease (multiple); and long QT syndrome (multiple). Is an ortholog of several human genes including KCNJ2 (potassium inwardly rectifying channel subfamily J member 2); KCNJ4 (potassium inwardly rectifying channel subfamily J member 4); and KCNJ5 (potassium inwardly rectifying channel subfamily J member 5). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model (16) | ||||||||
| Molecular_info | Corresponding_CDS | M02A10.2a | |||||||
| M02A10.2b | |||||||||
| M02A10.2c | |||||||||
| M02A10.2d | |||||||||
| M02A10.2e | |||||||||
| M02A10.2f | |||||||||
| Corresponding_CDS_history | M02A10.2:wp204 | ||||||||
| M02A10.2b:wp239 | |||||||||
| Corresponding_transcript | M02A10.2a.1 | ||||||||
| M02A10.2a.2 | |||||||||
| M02A10.2b.1 | |||||||||
| M02A10.2c.1 | |||||||||
| M02A10.2d.1 | |||||||||
| M02A10.2e.1 | |||||||||
| M02A10.2f.1 | |||||||||
| Other_sequence (12) | |||||||||
| Associated_feature | WBsf1003844 | ||||||||
| WBsf1003845 | |||||||||
| WBsf1003846 | |||||||||
| WBsf1022163 | |||||||||
| WBsf236953 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00050801 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00017113 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr16176 | ||||||||
| Expr16177 | |||||||||
| Expr16178 | |||||||||
| Expr1015830 | |||||||||
| Expr1154493 | |||||||||
| Expr2012824 | |||||||||
| Expr2031062 | |||||||||
| Drives_construct | WBCnstr00036415 | ||||||||
| WBCnstr00042793 | |||||||||
| Construct_product | WBCnstr00036415 | ||||||||
| WBCnstr00042793 | |||||||||
| Microarray_results (22) | |||||||||
| Expression_cluster (88) | |||||||||
| Interaction (15) | |||||||||
| Map_info | Map | X | Position | -19.5082 | |||||
| Positive | Positive_clone | M02A10 | Person_evidence | WBPerson654 | |||||
| WBPerson655 | |||||||||
| Inferred_automatically | From sequence, transcript, pseudogene data | ||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00006402 | ||||||||
| WBPaper00028146 | |||||||||
| WBPaper00034195 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00059550 | |||||||||
| WBPaper00064330 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
