WormBase Tree Display for Gene: WBGene00003173
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| WBGene00003173 | SMap | S_parent | Sequence | C50H2 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | mec-9 | Person_evidence | WBPerson95 | |||||
| Sequence_name | C50H2.3 | ||||||||
| Molecular_name | C50H2.3a | ||||||||
| C50H2.3a.1 | |||||||||
| CE05481 | |||||||||
| C50H2.3b | |||||||||
| CE08916 | |||||||||
| C50H2.3b.1 | |||||||||
| Other_name | CELE_C50H2.3 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | mec-9 | ||||||||
| DB_info | Database | WormQTL | gene | WBGene00003173 | |||||
| WormFlux | gene | WBGene00003173 | |||||||
| NDB | locus_tag | CELE_C50H2.3 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00003173|UniProtKB=Q18761 | |||||||
| family | PTHR24039 | ||||||||
| NCBI | gene | 179382 | |||||||
| RefSeq | protein | NM_001269224.3 | |||||||
| NM_001269225.3 | |||||||||
| TREEFAM | TREEFAM_ID | TF316678 | |||||||
| TrEMBL | UniProtAcc | G3MVG9 | |||||||
| Q18761 | |||||||||
| UniProt_GCRP | UniProtAcc | Q18761 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:31 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | mec | ||||||||
| Allele (119) | |||||||||
| Legacy_information | u27amber : touch insensitive lethargic. ES2 ME2. NA > 20 (e1494 u164amber etc.). | ||||||||
| [C.elegansII] u27amb : touch insensitive lethargic. ES2 ME2. OA>30: e1494, e1852, u164amb etc. Cloned: 2 kb and 3 kb transcripts, transpliced to SL1 and SL2, encode protein with Kunitztype serine protease inhibitor domains, EGF-like repeats. mec-9:GFP expressed in touch cells and PVD (3kb promoter) or more extensively (2kb promoter). [Chalfie and Au 1989; Huang and Chalfie 1994; TU] | |||||||||
| Strain | WBStrain00032822 | ||||||||
| WBStrain00004348 | |||||||||
| WBStrain00006234 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (15) | |||||||||
| Ortholog (21) | |||||||||
| Paralog (31) | |||||||||
| Structured_description | Concise_description | mec-9 encodes a predicted extracellular protein containing six EGF-like repeats,five Kunitz-type protease inhibitor domains, and a glutamic acid-rich region possibly involved in protein-protein interactions; mec-9 encodes two proteins, only one of which, MEC-9L, appears to be required for normal mechanosensory response to gentle touch and proper functioning of the touch receptor neurons; mec-9 interacts genetically with mec-5, which encodes a unique C. elegans collagen secreted by the hypodermis; MEC-9L is expressed and secreted by the touch receptor neurons. | Paper_evidence | WBPaper00002379 | |||||
| WBPaper00005666 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable calcium ion binding activity and serine-type endopeptidase inhibitor activity. Involved in positive regulation of multicellular organismal process and response to mechanical stimulus. Predicted to be located in extracellular region. Expressed in PVDL; PVDR; head neurons; touch receptor neurons; and ventral cord neurons. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C50H2.3a | |||||||
| C50H2.3b | |||||||||
| Corresponding_CDS_history | C50H2.3a:wp144 | ||||||||
| C50H2.3b:wp144 | |||||||||
| Corresponding_transcript | C50H2.3a.1 | ||||||||
| C50H2.3b.1 | |||||||||
| Other_sequence (14) | |||||||||
| Associated_feature | WBsf669266 | ||||||||
| WBsf669267 | |||||||||
| WBsf669268 | |||||||||
| WBsf1001008 | |||||||||
| WBsf1020239 | |||||||||
| WBsf234297 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00042982 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00012263 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00067621 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00112683 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00089014 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr268 | ||||||||
| Expr1026433 | |||||||||
| Expr1146947 | |||||||||
| Expr2013503 | |||||||||
| Expr2031737 | |||||||||
| Drives_construct | WBCnstr00004795 | ||||||||
| WBCnstr00036197 | |||||||||
| Construct_product | WBCnstr00036197 | ||||||||
| Microarray_results (23) | |||||||||
| Expression_cluster (161) | |||||||||
| Interaction (29) | |||||||||
| Map_info | Map | V | Position | 2.2108 | Error | 0.000399 | |||
| Well_ordered | |||||||||
| Positive | Inside_rearr | eDf1 | |||||||
| Positive_clone | C50H2 | Inferred_automatically | From sequence, transcript, pseudogene data | ||||||
| Negative | Negative_clone | F15H4 | |||||||
| Mapping_data | 2_point | 133 | |||||||
| Multi_point | 284 | ||||||||
| 3103 | |||||||||
| 3104 | |||||||||
| 4628 | |||||||||
| Pos_neg_data | 495 | ||||||||
| 1747 | |||||||||
| 1751 | |||||||||
| 3124 | |||||||||
| 3125 | |||||||||
| 3126 | |||||||||
| 3127 | |||||||||
| Reference (49) | |||||||||
| Method | Gene |
