WormBase Tree Display for Gene: WBGene00003414
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| WBGene00003414 | SMap | S_parent | Sequence | Y75B8A | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | mrp-8 | Person_evidence | WBPerson490 | |||||
| Sequence_name | Y75B8A.26 | ||||||||
| Molecular_name | Y75B8A.26 | ||||||||
| Y75B8A.26.1 | |||||||||
| CE43455 | |||||||||
| Other_name | CELE_Y75B8A.26 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | mrp-8 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:31 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 12 Jan 2009 16:59:00 | WBPerson1983 | Event | Acquires_merge | WBGene00043999 | ||||
| Acquires_merge | WBGene00043999 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | mrp | ||||||||
| Allele (523) | |||||||||
| Strain | WBStrain00031969 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (12) | |||||||||
| Ortholog (54) | |||||||||
| Paralog | WBGene00000477 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00003407 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00003408 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00003409 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00003410 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00003411 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00003412 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00003413 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | mrp-8 encodes a predicted ATP-binding cassette (ABC) transporter that is a member of the ABCC subfamily of ABC transporters that includes the multidrug resistance-associated proteins and the cystic fibrosis transmembrane conductance regulator; by homology, MRP-8 is predicted to function as an ATP-dependent organic anion transporter that transports molecules across the plasma membrane into the extracellular space; at present, the precise role of MRP-8 in C. elegans development and/or behavior is not yet known. | Paper_evidence | WBPaper00006421 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in arterial calcification of infancy; coronary artery disease; and pseudoxanthoma elasticum. Is an ortholog of human ABCC6 (ATP binding cassette subfamily C member 6). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:2738 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:57) | ||||
| DOID:0050644 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:57) | ||||||
| DOID:3393 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:57) | ||||||
| Molecular_info | Corresponding_CDS | Y75B8A.26 | |||||||
| Corresponding_CDS_history | Y75B8A.26:wp199 | ||||||||
| Corresponding_transcript | Y75B8A.26.1 | ||||||||
| Other_sequence | HBC03230_1 | ||||||||
| JI467379.1 | |||||||||
| Associated_feature | WBsf666491 | ||||||||
| WBsf717116 | |||||||||
| WBsf994609 | |||||||||
| WBsf994610 | |||||||||
| WBsf994611 | |||||||||
| WBsf1016171 | |||||||||
| WBsf1016172 | |||||||||
| WBsf227652 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00037844 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00058456 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1021872 | ||||||||
| Expr1161872 | |||||||||
| Expr2013693 | |||||||||
| Expr2031928 | |||||||||
| Microarray_results (24) | |||||||||
| Expression_cluster (110) | |||||||||
| Interaction (29) | |||||||||
| Map_info | Map | III | Position | 16.316 | Error | 0.022261 | |||
| Positive | Positive_clone | Y75B8A | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 5018 | |||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00027644 | ||||||||
| WBPaper00031484 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00064023 | |||||||||
| Remark | Sequence connection from [Sheps JA, Baillie DL] [040902 ck1] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
