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WormBase Tree Display for Gene: WBGene00003889

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Name Class

WBGene00003889SMapS_parentSequenceB0212
IdentityVersion1
NameCGC_nameosm-9Person_evidenceWBPerson242
Sequence_nameB0212.5
Molecular_nameB0212.5
B0212.5.1
CE20445
Other_namenss-2
CELE_B0212.5Accession_evidenceNDBBX284604
Public_nameosm-9
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:33WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classosm
Allele (120)
Legacy_information[C.elegansII] n1601 : defective in osmotic avoidance, also in nose touch avoidance (Not); Adp (partly defective adaptation to isoamyl alcohol and butanone); normal chemotaxis.OA5: n1516, n1603, n2473, ky10 (similar). [Colbert & Bargmann 1995; JT; KP; MT]
StrainWBStrain00023453
WBStrain00036458
WBStrain00005214
WBStrain00007483
WBStrain00052609
RNASeq_FPKM (74)
GO_annotation00010338
00010339
00010340
00010341
00010342
00010343
00010344
00010345
00010346
00010347
00010348
00010349
00010350
00010351
00010352
00010353
00010354
00010355
00010356
00010357
00010358
00010359
00010360
00010361
00010362
00010363
00010364
00010365
00010366
00111960
00111961
00111962
00111963
Ortholog (45)
ParalogWBGene00003838Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00003839Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00003840Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00003841Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
Structured_descriptionConcise_descriptionosm-9 encodes a TRPV channel homologous to capsaicin receptors; osm-9 is involved in sensory responses to a subset of chemical stimuli and to ASH neuron-mediated osmotic and mechanical stimuli; OSM-9 is also involved in adaptation to volatile odorants and salts; OSM-9 is expressed in a variety of sensory neurons and shows neuron-specific localization to either the cell body or the cilium.Paper_evidenceWBPaper00002166
WBPaper00002930
WBPaper00005150
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated20 Apr 2011 00:00:00
Automated_descriptionEnables calcium channel activity and temperature-gated cation channel activity. Involved in several processes, including heat acclimation; negative adaptation of signaling pathway; and nervous system process. Located in neuronal cell body; non-motile cilium; and perinuclear region of cytoplasm. Expressed in RIG; head mesodermal cell; rectal gland cell; sensory neurons; and uterine toroidal epithelial cell. Human ortholog(s) of this gene implicated in several diseases, including keratosis (multiple); motor neuron disease (multiple); and osteochondrodysplasia (multiple). Is an ortholog of human TRPV3 (transient receptor potential cation channel subfamily V member 3); TRPV4 (transient receptor potential cation channel subfamily V member 4); and TRPV5 (transient receptor potential cation channel subfamily V member 5).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_model (17)
Molecular_infoCorresponding_CDSB0212.5
Corresponding_transcriptB0212.5.1
Other_sequence (14)
Associated_featureWBsf667839
WBsf995982
Experimental_infoRNAi_result (14)
Expr_pattern (12)
Drives_constructWBCnstr00000837
WBCnstr00005979
WBCnstr00008561
WBCnstr00010985
WBCnstr00010991
WBCnstr00011000
WBCnstr00011004
WBCnstr00012945
WBCnstr00023098
WBCnstr00035811
Construct_productWBCnstr00000837
WBCnstr00006801
WBCnstr00010991
WBCnstr00011000
WBCnstr00011004
WBCnstr00012945
WBCnstr00020618
WBCnstr00035811
Regulate_expr_clusterWBPaper00049594:osm-9(ok1677)_NaCl(200mM)_upregulate
WBPaper00049594:osm-9(ok1677)_upregulated
Microarray_results (18)
Expression_cluster (103)
Interaction (116)
Anatomy_functionWBbtf0291
WBProcessWBbiopr:00000002
Map_infoMapIVPosition-3.15659Error0.016734
Well_ordered
PositivePositive_cloneB0212Inferred_automaticallyFrom sequence, transcript, pseudogene data
CX#2-12
Mapping_data2_point3729
3730
Multi_point1365
1366
Reference (225)
RemarkPossibly homologous to mammalian capsaicin receptor VR1. Some osm-9 mutants are sensitive to capsaicin.[bionet.celegans from Olsen]Curator_confirmedWBPerson1250
MethodGene