WormBase Tree Display for Gene: WBGene00004719

WBGene00004719 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: F15A2
  Identity: Version: 1
    Name: CGC_name: sad-1 Person_evidence: WBPerson42
      Sequence_name: F15A2.6
      Molecular_name: F15A2.6a
        F15A2.6a.1
        CE28218
        F15A2.6b
        CE40646
        F15A2.6b.1
      Other_name: CELE_F15A2.6 Accession_evidence: NDB BX284606
      Public_name: sad-1
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:36 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: sad
    Allele: WBVar00088438
      WBVar00260201
      WBVar01499887
      WBVar01499519
      WBVar01499888
      WBVar01602382
      WBVar01499710
      WBVar01679153
      WBVar01679154
      WBVar01679155
      WBVar01679156
      WBVar01679157
      WBVar01679158
      WBVar00088432
      WBVar00088433
      WBVar00088435
      WBVar01835277
      WBVar00088437
      WBVar01941703
      WBVar00088441
      WBVar02101672
      WBVar01759929
      WBVar01759930
      WBVar01759931
      WBVar01759932
      WBVar01759933
      WBVar02013720
      WBVar01759934
      WBVar01759935
      WBVar02013721
      WBVar00088152
      WBVar01759936
      WBVar02013722
      WBVar02013723
      WBVar01759937
      WBVar01759938
      WBVar02013724
      WBVar01759939
      WBVar01759940
      WBVar01759941
      WBVar00601547
      WBVar00601548
      WBVar01489258
      WBVar01572563
      WBVar01572564
      WBVar01572565
      WBVar01487973
      WBVar01572566
      WBVar01572567
      WBVar01572568
      WBVar01572569
      WBVar00262464
      WBVar01955082
      WBVar01955083
      WBVar01955084
      WBVar01907948
      WBVar01201774
      WBVar01201775
      WBVar01201776
      WBVar01201777
      WBVar01201778
      WBVar01201779
      WBVar01201780
      WBVar01201781
      WBVar01201782
      WBVar01201783
      WBVar01201784
      WBVar01201785
      WBVar00142510
      WBVar01472101
      WBVar01201786
      WBVar01472102
      WBVar01201787
      WBVar01472103
      WBVar01201788
      WBVar01201789
      WBVar02034870
      WBVar01201790
      WBVar01201791
      WBVar01201792
      WBVar01201793
      WBVar01201794
      WBVar01201795
      WBVar01201796
      WBVar01201797
      WBVar01201798
      WBVar02050673
      WBVar01201799
      WBVar01201800
      WBVar01201801
      WBVar01201802
      WBVar00522042
      WBVar00522043
      WBVar01201803
      WBVar00522044
      WBVar00216954
      WBVar01201804
      WBVar02080209
      WBVar01201805
      WBVar00522045
      WBVar00522046
      WBVar01201806
      WBVar01201807
      WBVar00522047
      WBVar00064636
      WBVar01201808
      WBVar00522048
      WBVar01201809
      WBVar00522049
      WBVar01201810
      WBVar00522050
      WBVar01201811
      WBVar00522051
      WBVar00522052
      WBVar01201812
      WBVar00522053
      WBVar01201813
      WBVar00522054
      WBVar01201814
      WBVar01201815
      WBVar00522055
      WBVar00522056
      WBVar01201816
      WBVar01201817
      WBVar00522057
      WBVar01201818
      WBVar00522058
      WBVar01201819
      WBVar00522059
      WBVar00522060
      WBVar01201820
      WBVar01201821
      WBVar00522061
      WBVar01201822
      WBVar00522062
      WBVar01201823
      WBVar00522063
      WBVar01928366
      WBVar01622059
      WBVar01928367
      WBVar00522064
      WBVar01201824
      WBVar01928368
      WBVar01201825
      WBVar00522065
      WBVar01928369
      WBVar01201826
      WBVar01928370
      WBVar01201827
      WBVar01787551
      WBVar01201828
      WBVar01928371
      WBVar01787552
      WBVar01201829
      WBVar02105995
      WBVar01928372
      WBVar01787553
      WBVar01928373
      WBVar01787554
      WBVar01201830
      WBVar01928374
      WBVar01787555
      WBVar01201831
      WBVar01201832
      WBVar01928375
      WBVar01787556
      WBVar01201833
      WBVar01928376
      WBVar01201834
      WBVar01928377
      WBVar02005352
      WBVar01201835
      WBVar01201836
      WBVar02005353
      WBVar00237198
      WBVar01201837
      WBVar01900259
      WBVar01820565
      WBVar02005354
      WBVar02027554
      WBVar01201838
      WBVar02005355
      WBVar01201839
      WBVar02027555
      WBVar01201840
      WBVar02027556
      WBVar01201841
      WBVar02071473
      WBVar01201842
      WBVar01201843
      WBVar01201844
      WBVar01201845
      WBVar01201846
      WBVar01201847
      WBVar01201848
      WBVar01201849
      WBVar01201850
      WBVar01527739
      WBVar01527740
      WBVar01201851
      WBVar01527741
      WBVar01201852
      WBVar01527742
      WBVar01201853
      WBVar01527743
      WBVar01201854
      WBVar01201855
      WBVar01527744
      WBVar01201856
      WBVar01527745
      WBVar00084170
      WBVar01201857
      WBVar01527746
      WBVar00084171
      WBVar01201858
      WBVar00084172
      WBVar01527747
      WBVar01201859
      WBVar01527748
      WBVar01201860
      WBVar01527749
      WBVar01527750
      WBVar01201861
      WBVar01201862
      WBVar02144468
      WBVar01703659
      WBVar01527751
      WBVar01201863
      WBVar01703660
      WBVar01527752
      WBVar01201864
      WBVar01703661
      WBVar01527753
      WBVar01527754
      WBVar01201865
      WBVar01703662
      WBVar02144475
      WBVar01201866
      WBVar01527755
      WBVar01703663
      WBVar01201867
      WBVar01527756
      WBVar01703664
      WBVar01201868
      WBVar01703665
      WBVar01527757
      WBVar01703666
      WBVar01201869
      WBVar01527758
      WBVar01527759
      WBVar01703667
      WBVar01201870
      WBVar01201871
      WBVar01527760
      WBVar01703668
      WBVar01201872
      WBVar01527761
      WBVar01703669
      WBVar01201873
      WBVar01703670
      WBVar01527762
      WBVar01201874
      WBVar01703671
      WBVar01527763
      WBVar01703672
      WBVar01527764
      WBVar01201875
      WBVar01703673
      WBVar01527765
      WBVar01201876
      WBVar01703674
      WBVar01527766
      WBVar01201877
      WBVar01703675
      WBVar01201878
      WBVar01527767
      WBVar01703676
      WBVar01527768
      WBVar01703677
      WBVar01703678
      WBVar01703679
      WBVar01703680
      WBVar01703681
      WBVar01703682
      WBVar01703683
      WBVar01703684
      WBVar01498960
      WBVar01500067
    Strain: WBStrain00002260
      WBStrain00001646
      WBStrain00005268
      WBStrain00023494
    RNASeq_FPKM (74)
    GO_annotation (35)
    Ortholog (44)
    Paralog (19)
    Structured_description: Concise_description: sad-1 encodes a novel serine/threonine protein kinase; SAD-1 activity is required for several aspects of presynaptic development, including termination of axon outgrowth and presynaptic vesicle clustering, in GABAergic motor neurons and the ASI amphid chemosensory neuron; in addition, SAD-1 functions in a complex with STRD-1, with which it physically interacts in vivo, to regulate axonal-dendritic polarity and synapse organization; SAD-1 is expressed in the nervous system, where it localizes asymmetrically to the synapse-rich regions of axons; SAD-1 localization to synapses depends upon STRD-1; SAD-1 exhibits kinase activity in vitro, phosphorylating recombinant human Tau. Paper_evidence: WBPaper00004523
            WBPaper00035545
          Curator_confirmed: WBPerson1843
          Date_last_updated: 28 Jun 2010 00:00:00
      Automated_description: Enables protein kinase activity. Involved in cellular component organization; cellular localization; and establishment or maintenance of cell polarity. Located in axon and dendrite. Expressed in nervous system. Is an ortholog of human BRSK1 (BR serine/threonine kinase 1) and BRSK2 (BR serine/threonine kinase 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F15A2.6a
      F15A2.6b
    Corresponding_CDS_history: F15A2.6:wp53
    Corresponding_transcript: F15A2.6a.1
      F15A2.6b.1
    Other_sequence (26)
    Associated_feature (13)
  Experimental_info: RNAi_result (18)
    Expr_pattern (18)
    Drives_construct: WBCnstr00000850
      WBCnstr00002485
      WBCnstr00004357
      WBCnstr00005298
      WBCnstr00013124
      WBCnstr00013265
      WBCnstr00041292
      WBCnstr00041293
    Construct_product (18)
    Antibody: WBAntibody00000343
      WBAntibody00001193
    Microarray_results (30)
    Expression_cluster (173)
    Interaction (33)
  Map_info: Map: X Position: 12.6561 Error: 0.012226
    Well_ordered
    Positive: Positive_clone: F15A2 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4019
        4196
        4276
  Reference (54)
  Remark: [email 93 from R. Lee and cgc4523]
  Method: Gene