WormBase Tree Display for Gene: WBGene00004971

WBGene00004971 SMap: S_parent: Sequence: ZK617
  Identity: Version: 1
    Name: CGC_name: spe-17 Person_evidence: WBPerson252
      Sequence_name: ZK617.3
      Molecular_name: ZK617.3
        ZK617.3.1
        CE28723
      Other_name: CELE_ZK617.3 Accession_evidence: NDB BX284604
      Public_name: spe-17
    DB_info: Database: AceView gene 4M779
        WormQTL gene WBGene00004971
        WormFlux gene WBGene00004971
        NDB locus_tag CELE_ZK617.3
        NCBI gene 178136
        RefSeq protein NM_069874.5
        SwissProt UniProtAcc P34890
        TREEFAM TREEFAM_ID TF321408
        UniProt_GCRP UniProtAcc P34890
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:37 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: spe
    Allele (21)
    Legacy_information: [C.elegansII] Mutation defined by hcDf1, hDf13; hermaphrodite brood size 3, abnormal spermatogenesis with ribosomes attaching to fibrous body-membranous organelle. Cloned: 0.56 kb transcript, encodes 142 aa novel predicted protein, highly charged, Ser and Thr rich. [L'Hernault et al. 1993; SL]
    Strain: WBStrain00032672
      WBStrain00037145
      WBStrain00037204
    RNASeq_FPKM (74)
    GO_annotation: 00044828
      00044829
      00044830
    Ortholog (16)
    Structured_description: Concise_description: spe-17 is predicted to encode a hydrophilic serine/threonine rich protein with no significant homology to any known protein; spe-17 is required for the proper development of spermatids into sperm during spermatogenesis and thus for fertility; specifically, spe-17 is required for the correct partitioning of organelles and sperm components into specialized Golgi-derived fibrous body-membranous organelle (FB-MO) complexes during spermatid formation. Paper_evidence: WBPaper00001748
            WBPaper00036251
          Curator_confirmed: WBPerson324
          Date_last_updated: 12 Aug 2010 00:00:00
      Automated_description: Involved in spermatid development. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: ZK617.3
    Corresponding_CDS_history: ZK617.3:wp57
    Corresponding_transcript: ZK617.3.1
    Other_sequence: CJC03392_1
    Associated_feature: WBsf716793
      WBsf998010
      WBsf1018308
      WBsf229231
  Experimental_info: RNAi_result: WBRNAi00000397 Inferred_automatically: RNAi_primary
      WBRNAi00059560 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1013085
      Expr1162976
      Expr2016034
    Drives_construct: WBCnstr00035300
      WBCnstr00039980
    Construct_product: WBCnstr00035300
      WBCnstr00039980
    Microarray_results (18)
    Expression_cluster: WBPaper00037055:DAF-16_binding_DNA
      WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:AVA-neuron_L1-larva_expressed
      WBPaper00037950:AVE-neuron_L1-larva_expressed
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00038237:age-1_upregulated_intestine_rescue
      WBPaper00038237:age-1_upregulated_neuron_rescue
      WBPaper00038237:age-1_upregulated_nontransgenic
      WBPaper00038438:S.marcescens_24hr_downregulated_TilingArray
      WBPaper00040560:hpl-2_embryo_downregulated
      WBPaper00041071:spe-44_downregulated
      WBPaper00042194:nhr-114(RNAi)_upregulated
      WBPaper00042215:wdr-23(tm1817)_upregulated
      WBPaper00044037:eat-2_upregulated
      WBPaper00044316:CH3HgCl_7.5uM_upregulated
      WBPaper00044616:alg-3-4_upregulated_gene
      WBPaper00044736:rising_dev_expression
      WBPaper00045521:Spermatogenic
      WBPaper00045974:NSM_enriched_totalRNA_tiling
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h
      WBPaper00046805:csr-1(RNAi)_upregulated_Set1
      WBPaper00046805:csr-1(RNAi)_upregulated_Set2
      WBPaper00046805:P-granule-RNAi_upregulated_Set1
      WBPaper00048611:MnCl2_downregulated
      WBPaper00049498:npr-1(ur89)_regulated_2
      WBPaper00049545:cco-1(RNAi)_downregulated
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031)
      WBPaper00049920:Glucose-Diet_upregulated_N2
      WBPaper00049942:HeatShock_downregulated_hsf-1(RNAi)
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00050231:male_enriched
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053295:lin-22(icb38)_downregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053318:Aging_downregulated_mRNA_N2
      WBPaper00053318:mir-71(n4115)_downregulated_mRNA
      WBPaper00053388:dauer_regulated_Cluster6
      WBPaper00053599:female_vs_male_downregulated
      WBPaper00053771:up_at_3h-NaCl
      WBPaper00055013:hmg-3(bar24)_downregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055386:daf-2(e1370)_upregulated
      WBPaper00055386:eat-2(ad465)_upregulated
      WBPaper00055648:sperm_expressed
      WBPaper00055971:nhl-2(ok818)_20C_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056090:E.faecalis_upregulated_N2
      WBPaper00056161:male_enriched_siRNA
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00058691:cfp-1(tm6369)_upregulated
      WBPaper00058691:sin-3(tm1276)_upregulated
      WBPaper00059117:B.subtilis_upregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061081:E.faecalis_upregulated_N2
      WBPaper00061274:hypergravity_10xg_upregulated
      WBPaper00061424:Diet_MYb131_upregulated
      WBPaper00061479:mep-1(ne4629)_upregulated
      WBPaper00061527:Y40H4A.2-ZK1053.2
      WBPaper00062156:jmjd-5(zr1234)_upregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062456:doxycycline_upregulated_CB4856_transcript
      WBPaper00062672:let-418(n3536)_upregulated
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064505:tamoxifen_downregulated
      WBPaper00064539:nhr-114(gk849)_downregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00064728:cpl-1(W32AY35A)_upregulated
      WBPaper00064933:bcf-1(ylf1)_upregulated_transcript
      WBPaper00065086:N2_N.ferruginous_regulated
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065096:npr-8(ok1439)_upregulated_Day1_25C
      WBPaper00065096:npr-8(ok1439)_upregulated_Day10_20C
      WBPaper00065096:npr-8(ok1439)_upregulated_Day10_25C
      WBPaper00066038:mip-1(how5)_upregulated
      WBPaper00066085:hda-3(ok1991)_upregulated
      WBPaper00066093:E.coli-purE_upregulated
      WBPaper00066110:Cisplatin_upregulated_diploid
      WBPaper00066110:Doxorubicin_upregulated_diploid
      WBPaper00066110:tetraploid_vs_diploid_upregulated
      WBPaper00066118:cyclobutrifluram_upregulated
      WBPaper00066232:ash-2(RNAi)_downregulated_WT
      cgc4489_group_11
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026952:class_B
      WBPaper00036130:mir-243_up_regulated
      WBPaper00036286:Pattern_E
      WBPaper00038172:aak-2overexpression_up_regulated
      WBPaper00040210:Chlorpyrifos_16C_regulated
      WBPaper00040858:eQTL_age_regulated_aging
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00045263:0.1mM-paraquat_downregulated
      WBPaper00045263:isp-1(qm150)_downregulated
      WBPaper00045263:nuo-6(qm200)_downregulated
      WBPaper00045263:ProLongevity-mtROS_downregulated
      WBPaper00045673:colistin_downregulated
      WBPaper00048989:N2_rapamycin_upregulated
      WBPaper00056330:mrps-5(RNAi)_upregulated
      [cgc6390]:spermatogenesis-enriched
    Interaction (88)
    WBProcess: WBbiopr:00000069
  Map_info: Map: IV Position: 5.49134 Error: 0.013767
    Well_ordered
    Positive: Positive_clone: ZK617 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data
  Reference (15)
  Method: Gene