| WBGene00006782 | SMap | S_parent | Sequence | C04F5 |
|---|
| Identity | Version | 2 |
| | Name | CGC_name | unc-46 | Paper_evidence | WBPaper00000031 |
| | | Sequence_name | C04F5.3 |
| | | Molecular_name | C04F5.3 |
| | | | C04F5.3.1 |
| | | | CE27791 |
| | | Other_name | CELE_C04F5.3 | Accession_evidence | NDB | BX284605 |
| | | Public_name | unc-46 |
| | DB_info | Database | AceView | gene | 5F576 |
| | | | WormQTL | gene | WBGene00006782 |
| | | | WormFlux | gene | WBGene00006782 |
| | | | NDB | locus_tag | CELE_C04F5.3 |
| | | | NCBI | gene | 178897 |
| | | | RefSeq | protein | NM_071964.5 |
| | | | TREEFAM | TREEFAM_ID | TF320931 |
| | | | TrEMBL | UniProtAcc | Q9GZD5 |
| | | | UniProt_GCRP | UniProtAcc | Q9GZD5 |
| | Species | Caenorhabditis elegans |
| | History | Version_change | 1 | 07 Apr 2004 11:29:42 | WBPerson1971 | Event | Imported | Initial conversion from geneace |
| | | | 2 | 23 Mar 2005 14:05:09 | WBPerson2970 | Event | Acquires_merge | WBGene00015445 |
| | | Acquires_merge | WBGene00015445 |
| | Status | Live |
| Gene_info | Biotype | SO:0001217 |
| | Gene_class | unc |
| | Reference_allele | WBVar00143011 |
| | Allele (38) |
| | Legacy_information | e177 : shrinker contracts both dorsally and ventrally when prodded slow good forward movement poor backing; slightly small. ES3 ME2. NA3 (e300 e642). |
| | | [C.elegansII] e177 : shrinker contracts both dorsally and ventrally when prodded, slow, good forward movement, poor backing; slightly small. ES3 ME2. OA2: e300, e642. [Brenner 1974; McIntire et al. 1993; MT] |
| | Strain (163) |
| | RNASeq_FPKM (74) |
| | GO_annotation | 00093030 |
| | | 00093031 |
| | Ortholog (29) |
| | Structured_description | Concise_description | unc-46 encodes a type I transmembrane protein that contains a single motif similar to the LAMP (lysosomal associated membrane glycoprotein) domain; UNC-46 and UNC-47, the C. elegans vesicular GABA transporter, are required in GABAergic neurons for loading GABA into synaptic vesicles and thus, for all GABA-mediated behaviors; a rescuing UNC-46::GFP fusion protein localizes to synaptic varicosities in the dorsal and ventral nerve cords; UNC-46 and UNC-47 are mutually required for sorting/localization to synaptic vesicles; when overexpressed, unc-47 can rescue unc-46 mutant animals. | Paper_evidence | WBPaper00030788 |
| | | | | Curator_confirmed | WBPerson1843 |
| | | | | Date_last_updated | 12 Jun 2008 00:00:00 |
| | | Automated_description | Located in cytoplasmic vesicle and neuromuscular junction. Expressed in GLR and neurons. | Paper_evidence | WBPaper00065943 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | | WBPerson37462 |
| | | | | Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase |
| | | | | Date_last_updated | 29 Nov 2023 00:00:00 |
| Molecular_info | Corresponding_CDS | C04F5.3 |
| | Corresponding_transcript | C04F5.3.1 |
| | Other_sequence | Acan_isotig12346 |
| | Associated_feature | WBsf652609 |
| | | WBsf999935 |
| | | WBsf233650 |
| Experimental_info | RNAi_result | WBRNAi00090126 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00039641 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00028449 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00089966 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00010134 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00089726 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00090284 | Inferred_automatically | RNAi_primary |
| | Expr_pattern | Expr4785 |
| | | Expr4786 |
| | | Expr13159 |
| | | Expr15441 |
| | | Expr1021811 |
| | | Expr1143737 |
| | | Expr2017879 |
| | | Expr2036015 |
| | Drives_construct | WBCnstr00001640 |
| | | WBCnstr00008362 |
| | | WBCnstr00008363 |
| | | WBCnstr00012243 |
| | | WBCnstr00020699 |
| | | WBCnstr00034155 |
| | Construct_product | WBCnstr00001640 |
| | | WBCnstr00034155 |
| | | WBCnstr00038183 |
| | Microarray_results (20) |
| | Expression_cluster | WBPaper00024970:GABAergic_neuron_specific |
| | | WBPaper00030922:glycosylated_protein |
| | | WBPaper00032425:down_in_zfp-1 |
| | | WBPaper00033070:Rhine_downregulated |
| | | WBPaper00037682:sma-2_sma-4_upregulated |
| | | WBPaper00037946:LIN-39_interacting |
| | | WBPaper00037950:A-class-motor-neurons_L1-larva_expressed |
| | | WBPaper00037950:all-neurons_L1-larva_expressed |
| | | WBPaper00037950:all-neurons_L2-larva_expressed |
| | | WBPaper00037950:AVA-neuron_L1-larva_expressed |
| | | WBPaper00037950:AVE-neuron_L1-larva_expressed |
| | | WBPaper00037950:coelomocytes_L1-larva_expressed |
| | | WBPaper00037950:coelomocytes_L2-larva_expressed |
| | | WBPaper00037950:dopaminergic-neurons_L1-larva_expressed |
| | | WBPaper00037950:GABAergic-motor-neurons_CoreEnriched |
| | | WBPaper00037950:GABAergic-motor-neurons_embryo_enriched |
| | | WBPaper00037950:GABAergic-motor-neurons_embryo_SelectivelyEnriched |
| | | WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed |
| | | WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed |
| | | WBPaper00037950:GABAergic-motor-neurons_larva_enriched |
| | | WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed |
| | | WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq |
| | | WBPaper00038438:Harposporium_24hr_upregulated_RNAseq |
| | | WBPaper00042194:nhr-114(RNAi)_downregulated |
| | | WBPaper00042561:smgl-1(RNAi)_upregulated |
| | | WBPaper00044037:eat-2_upregulated |
| | | WBPaper00044656:tatn-1(qd182)_upregulated |
| | | WBPaper00044736:flat_dev_expression |
| | | WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated |
| | | WBPaper00045420:fertilization_downregulated_transcript |
| | | WBPaper00048988:neuron_enriched |
| | | WBPaper00048988:neuron_expressed |
| | | WBPaper00049377:MWCNT_upregulated |
| | | WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult |
| | | WBPaper00050488:20C_vs_25C_regulated_N2_adult |
| | | WBPaper00050488:adult_vs_dauer_regulated_N2_20C |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult |
| | | WBPaper00050990:GABAergic-neuron_expressed |
| | | WBPaper00050990:intestine_expressed |
| | | WBPaper00053302:zidovudine_72h_regulated |
| | | WBPaper00055354:Psora-Allantoin_downregulated |
| | | WBPaper00055354:Rapamycin-Allantoin_downregulated |
| | | WBPaper00055354:Rapamycin-Metformin_downregulated |
| | | WBPaper00055354:Rapamycin-Psora-Allantoin_downregulated |
| | | WBPaper00055354:Rapamycin-Rifampicin_downregulated |
| | | WBPaper00055354:Rifampicin-Allantoin_downregulated |
| | | WBPaper00055354:Rifampicin-Psora_downregulated |
| | | WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047) |
| | | WBPaper00058969:RIS_enriched |
| | | WBPaper00059027:neuron-synapses_depleted |
| | | WBPaper00059421:daf-3(mgDf90)_downregulated |
| | | WBPaper00060014:set-2(tm1630)_downregulated |
| | | WBPaper00060661:hypoxia_upregulated |
| | | WBPaper00060661:sensory-neuron_enriched |
| | | WBPaper00060811:L1_vs_adult_upregulated_neural |
| | | WBPaper00060909:atfs-1(cmh15)_downregulated |
| | | WBPaper00061340:ALM_PLM |
| | | WBPaper00061340:AVB |
| | | WBPaper00061340:AVL |
| | | WBPaper00061340:DA_DB |
| | | WBPaper00061340:DD |
| | | WBPaper00061340:OLQ |
| | | WBPaper00061340:PVT |
| | | WBPaper00061340:RIB |
| | | WBPaper00061340:RIS |
| | | WBPaper00061340:RME |
| | | WBPaper00061341:28C_24h_upregulated |
| | | WBPaper00061341:28C_48h_upregulated |
| | | WBPaper00061527:C25E10.11-F35H12.1 |
| | | WBPaper00061572:oleic-acid-specific_mating_downregulated |
| | | WBPaper00061651:AVL_enriched |
| | | WBPaper00061651:DVB_enriched |
| | | WBPaper00061651:RIA_enriched |
| | | WBPaper00061651:RIB_enriched |
| | | WBPaper00061651:RIS_enriched |
| | | WBPaper00061651:RMD_DV_enriched |
| | | WBPaper00061651:RME_DV_enriched |
| | | WBPaper00061651:RME_LR_enriched |
| | | WBPaper00061651:VD_DD_enriched |
| | | WBPaper00061902:camt-1(ok515)_regulated_RMG |
| | | WBPaper00061995:mter-4(syb3662syb3403)_downregulated |
| | | WBPaper00062103:neuron_enriched |
| | | WBPaper00062159:hda-2(ok1479)_upregulated |
| | | WBPaper00062325:muscle_depleted_coding-RNA |
| | | WBPaper00065096:25C_vs_20C_downregulated |
| | | WBPaper00065096:Day10_vs_Day1_downregulated |
| | | WBPaper00065096:npr-8(ok1439)_upregulated_Day1_25C |
| | | WBPaper00065623:43 |
| | | WBPaper00065749:Heat-Shock_downregulated_N2 |
| | | WBPaper00065841:10_0 |
| | | WBPaper00065841:52_0 |
| | | WBPaper00065841:68_0 |
| | | WBPaper00065841:68_1 |
| | | WBPaper00065841:75_0 |
| | | WBPaper00065841:83_0 |
| | | WBPaper00065841:86_0 |
| | | WBPaper00065841:109_0 |
| | | WBPaper00065841:118_0 |
| | | WBPaper00065841:121_0 |
| | | WBPaper00065841:144_0 |
| | | cgc4489_group_17 |
| | | WBPaper00025141:N2_Expressed_Genes |
| | | WBPaper00030839:Larval_Pan_Neuronal |
| | | WBPaper00031003:0hr_muscle_depleted |
| | | WBPaper00031003:total_muscle_depleted |
| | | WBPaper00031532:Larva_Pan_Neuronal_Enriched |
| | | WBPaper00034661:AgNPs_downregulated |
| | | WBPaper00040876:mir-35_downregulated |
| | | WBPaper00041939:control_vs_UVC-EtBr-exposed_51h |
| | | WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_51h |
| | | WBPaper00047070:N2_starvation_upregulated |
| | | WBPaper00048563:L1_DD_enriched |
| | | WBPaper00048989:N2_allantoin_downregulated |
| | | WBPaper00048989:N2_rapamycin_upregulated |
| | | WBPaper00057098:SiO2-nanoparticles_upregulated |
| | Interaction | WBInteraction000502940 |
| | | WBInteraction000502941 |
| | | WBInteraction000502942 |
| | | WBInteraction000518962 |
| | WBProcess | WBbiopr:00000010 |
| Map_info | Map | V | Position | -2.52065 | Error | 0.028521 |
| | Well_ordered |
| | Positive | Inside_rearr | nDf32 |
| | | | yDp1 |
| | | | nDf33 |
| | | | sDf26 |
| | | | rT1 |
| | | Positive_clone | C04F5 | Inferred_automatically | From sequence, transcript, pseudogene data |
| | Mapping_data | 2_point (27) |
| | | Multi_point (41) |
| | | Pos_neg_data | 845 |
| | | | 2134 |
| | | | 3076 |
| | | | 3259 |
| Reference (65) |
| Method | Gene |
