WormBase Tree Display for Gene: WBGene00006814
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WBGene00006814 | SMap | S_parent | Sequence | B0496 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 3 | |||||||
Name | CGC_name | unc-82 | Person_evidence | WBPerson261 | |||||
Sequence_name | B0496.3 | ||||||||
Molecular_name (29) | |||||||||
Other_name | CELE_B0496.3 | Accession_evidence | NDB | BX284604 | |||||
Public_name | unc-82 | ||||||||
DB_info | Database (14) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:43 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
2 | 12 Jun 2007 15:08:34 | WBPerson2970 | Event | Acquires_merge | WBGene00015212 | ||||
3 | 27 Nov 2009 10:33:57 | WBPerson10213 | Event | Acquires_merge | WBGene00015213 | ||||
Acquires_merge | WBGene00015212 | ||||||||
WBGene00015213 | |||||||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | unc | ||||||||
Reference_allele | WBVar00143842 | ||||||||
Allele (253) | |||||||||
Possibly_affected_by | WBVar02153065 | ||||||||
Legacy_information | e1220 : slow good movement abnormal reduced muscle birefringence abnormal body muscle ultrastruture with enlarged thick filaments etc. ES2 ME2. NA9 (e1323 r194 etc. : all resemble e1220). | ||||||||
See also e1220, e1323 | |||||||||
[C.elegansII] e1220 : slow, good movement, abnormal reduced muscle birefringence; abnormal body muscle ultrastructure with enlarged thick filaments; weaker pharyngeal muscle abnormalities. ES2 ME2. OA>5: e1323, r194, st1323 etc. (all resemble e1220). [Waterston and Brenner 1980; RW] | |||||||||
Strain | WBStrain00033499 | ||||||||
WBStrain00033522 | |||||||||
WBStrain00033523 | |||||||||
WBStrain00037392 | |||||||||
WBStrain00004275 | |||||||||
WBStrain00004300 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (18) | |||||||||
Ortholog (45) | |||||||||
Paralog (19) | |||||||||
Structured_description | Concise_description | unc-82 encodes a serine/threonine kinase related to the human ARK5/SNARK (NUAK1/NUAK2) and the PAR-1 and SNF1/AMP-Activated kinase (AMPK) protein kinase families; during development, UNC-82 activity is required for proper organization of internal (membrane-distal) proteins of myosin thick filaments and M-lines in conjunction with embryonic elongation; an UNC-82::GFP reporter fusion is expressed in muscle cells and is associated with M lines; UNC-82::GFP expression is also seen in the pharynx. | Paper_evidence | WBPaper00035423 | |||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 04 Jan 2011 00:00:00 | ||||||||
Automated_description | A structural constituent of muscle. Involved in striated muscle myosin thick filament assembly and striated muscle paramyosin thick filament assembly. Located in M band. Expressed in body wall musculature. Human ortholog(s) of this gene implicated in anencephaly. Is an ortholog of human NUAK1 (NUAK family kinase 1) and NUAK2 (NUAK family kinase 2). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:0060668 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:29558) | ||||
DOID:13223 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:14311) | ||||||
Molecular_info | Corresponding_CDS | B0496.3a | |||||||
B0496.3b | |||||||||
B0496.3c | |||||||||
B0496.3d | |||||||||
B0496.3e | |||||||||
B0496.3f | |||||||||
B0496.3g | |||||||||
B0496.3h | |||||||||
B0496.3i | |||||||||
Corresponding_CDS_history | B0496.3a:wp187 | ||||||||
B0496.3a:wp209 | |||||||||
B0496.3b:wp187 | |||||||||
B0496.3b:wp209 | |||||||||
B0496.3c:wp209 | |||||||||
Corresponding_transcript (11) | |||||||||
Other_sequence (35) | |||||||||
Associated_feature (30) | |||||||||
Gene_product_binds | WBsf919647 | ||||||||
Experimental_info | RNAi_result | WBRNAi00098424 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00091772 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00090133 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00039121 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00090478 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00039122 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00091736 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00091706 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00092808 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00090525 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00091676 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00091721 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00009817 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00039120 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00090431 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00089755 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00089974 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00092809 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00091691 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00108368 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00091751 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00090292 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00009816 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00090384 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00039119 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr8836 | ||||||||
Expr1015480 | |||||||||
Expr1032879 | |||||||||
Expr1143277 | |||||||||
Expr2017911 | |||||||||
Expr2036047 | |||||||||
Drives_construct | WBCnstr00007842 | ||||||||
WBCnstr00013549 | |||||||||
WBCnstr00034140 | |||||||||
Construct_product | WBCnstr00007842 | ||||||||
WBCnstr00013549 | |||||||||
WBCnstr00034140 | |||||||||
WBCnstr00041813 | |||||||||
WBCnstr00041814 | |||||||||
Microarray_results (53) | |||||||||
Expression_cluster (211) | |||||||||
Interaction (55) | |||||||||
Map_info | Map | IV | Position | 3.33492 | Error | 0.000317 | |||
Positive | Positive_clone | B0496 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Mapping_data | 2_point | 108 | |||||||
Multi_point | 286 | ||||||||
912 | |||||||||
913 | |||||||||
914 | |||||||||
915 | |||||||||
Pos_neg_data | 3262 | ||||||||
8144 | |||||||||
8145 | |||||||||
Reference (40) | |||||||||
Method | Gene |