WormBase Tree Display for Gene: WBGene00006814
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| WBGene00006814 | SMap | S_parent | Sequence | B0496 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | unc-82 | Person_evidence | WBPerson261 | |||||
| Sequence_name | B0496.3 | ||||||||
| Molecular_name (29) | |||||||||
| Other_name | CELE_B0496.3 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | unc-82 | ||||||||
| DB_info | Database (14) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:43 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 12 Jun 2007 15:08:34 | WBPerson2970 | Event | Acquires_merge | WBGene00015212 | ||||
| 3 | 27 Nov 2009 10:33:57 | WBPerson10213 | Event | Acquires_merge | WBGene00015213 | ||||
| Acquires_merge | WBGene00015212 | ||||||||
| WBGene00015213 | |||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | unc | ||||||||
| Reference_allele | WBVar00143842 | ||||||||
| Allele (253) | |||||||||
| Possibly_affected_by | WBVar02153065 | ||||||||
| Legacy_information | e1220 : slow good movement abnormal reduced muscle birefringence abnormal body muscle ultrastruture with enlarged thick filaments etc. ES2 ME2. NA9 (e1323 r194 etc. : all resemble e1220). | ||||||||
| See also e1220, e1323 | |||||||||
| [C.elegansII] e1220 : slow, good movement, abnormal reduced muscle birefringence; abnormal body muscle ultrastructure with enlarged thick filaments; weaker pharyngeal muscle abnormalities. ES2 ME2. OA>5: e1323, r194, st1323 etc. (all resemble e1220). [Waterston and Brenner 1980; RW] | |||||||||
| Strain | WBStrain00033499 | ||||||||
| WBStrain00033522 | |||||||||
| WBStrain00033523 | |||||||||
| WBStrain00037392 | |||||||||
| WBStrain00004275 | |||||||||
| WBStrain00004300 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (18) | |||||||||
| Ortholog (45) | |||||||||
| Paralog (19) | |||||||||
| Structured_description | Concise_description | unc-82 encodes a serine/threonine kinase related to the human ARK5/SNARK (NUAK1/NUAK2) and the PAR-1 and SNF1/AMP-Activated kinase (AMPK) protein kinase families; during development, UNC-82 activity is required for proper organization of internal (membrane-distal) proteins of myosin thick filaments and M-lines in conjunction with embryonic elongation; an UNC-82::GFP reporter fusion is expressed in muscle cells and is associated with M lines; UNC-82::GFP expression is also seen in the pharynx. | Paper_evidence | WBPaper00035423 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 04 Jan 2011 00:00:00 | ||||||||
| Automated_description | A structural constituent of muscle. Involved in striated muscle myosin thick filament assembly and striated muscle paramyosin thick filament assembly. Located in M band. Expressed in body wall musculature. Human ortholog(s) of this gene implicated in anencephaly. Is an ortholog of human NUAK1 (NUAK family kinase 1) and NUAK2 (NUAK family kinase 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0060668 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:29558) | ||||
| DOID:13223 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:14311) | ||||||
| Molecular_info | Corresponding_CDS | B0496.3a | |||||||
| B0496.3b | |||||||||
| B0496.3c | |||||||||
| B0496.3d | |||||||||
| B0496.3e | |||||||||
| B0496.3f | |||||||||
| B0496.3g | |||||||||
| B0496.3h | |||||||||
| B0496.3i | |||||||||
| Corresponding_CDS_history | B0496.3a:wp187 | ||||||||
| B0496.3a:wp209 | |||||||||
| B0496.3b:wp187 | |||||||||
| B0496.3b:wp209 | |||||||||
| B0496.3c:wp209 | |||||||||
| Corresponding_transcript (11) | |||||||||
| Other_sequence (35) | |||||||||
| Associated_feature (30) | |||||||||
| Gene_product_binds | WBsf919647 | ||||||||
| Experimental_info | RNAi_result (25) | ||||||||
| Expr_pattern | Expr8836 | ||||||||
| Expr1015480 | |||||||||
| Expr1032879 | |||||||||
| Expr1143277 | |||||||||
| Expr2017911 | |||||||||
| Expr2036047 | |||||||||
| Drives_construct | WBCnstr00007842 | ||||||||
| WBCnstr00013549 | |||||||||
| WBCnstr00034140 | |||||||||
| Construct_product | WBCnstr00007842 | ||||||||
| WBCnstr00013549 | |||||||||
| WBCnstr00034140 | |||||||||
| WBCnstr00041813 | |||||||||
| WBCnstr00041814 | |||||||||
| Microarray_results (53) | |||||||||
| Expression_cluster (211) | |||||||||
| Interaction (55) | |||||||||
| Map_info | Map | IV | Position | 3.33492 | Error | 0.000317 | |||
| Positive | Positive_clone | B0496 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | 2_point | 108 | |||||||
| Multi_point | 286 | ||||||||
| 912 | |||||||||
| 913 | |||||||||
| 914 | |||||||||
| 915 | |||||||||
| Pos_neg_data | 3262 | ||||||||
| 8144 | |||||||||
| 8145 | |||||||||
| Reference | WBPaper00000461 | ||||||||
| WBPaper00000488 | |||||||||
| WBPaper00000536 | |||||||||
| WBPaper00000608 | |||||||||
| WBPaper00000769 | |||||||||
| WBPaper00000785 | |||||||||
| WBPaper00001230 | |||||||||
| WBPaper00001276 | |||||||||
| WBPaper00001344 | |||||||||
| WBPaper00001352 | |||||||||
| WBPaper00001394 | |||||||||
| WBPaper00001662 | |||||||||
| WBPaper00001724 | |||||||||
| WBPaper00001736 | |||||||||
| WBPaper00001894 | |||||||||
| WBPaper00012563 | |||||||||
| WBPaper00013649 | |||||||||
| WBPaper00013853 | |||||||||
| WBPaper00015332 | |||||||||
| WBPaper00015926 | |||||||||
| WBPaper00018834 | |||||||||
| WBPaper00023418 | |||||||||
| WBPaper00026475 | |||||||||
| WBPaper00026505 | |||||||||
| WBPaper00027258 | |||||||||
| WBPaper00028027 | |||||||||
| WBPaper00030705 | |||||||||
| WBPaper00033099 | |||||||||
| WBPaper00033478 | |||||||||
| WBPaper00034940 | |||||||||
| WBPaper00035031 | |||||||||
| WBPaper00035423 | |||||||||
| WBPaper00036199 | |||||||||
| WBPaper00038487 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00047354 | |||||||||
| WBPaper00050557 | |||||||||
| WBPaper00052005 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00066314 | |||||||||
| Method | Gene |
