WormBase Tree Display for Gene: WBGene00012832
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| WBGene00012832 | SMap | S_parent | Sequence | Y43F8C | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | dmd-3 | Person_evidence | WBPerson1375 | |||||
| Sequence_name | Y43F8C.10 | ||||||||
| Molecular_name | Y43F8C.10a | ||||||||
| Y43F8C.10a.1 | |||||||||
| CE39835 | |||||||||
| Y43F8C.10b | |||||||||
| CE44151 | |||||||||
| Y43F8C.10b.1 | |||||||||
| Other_name | CELE_Y43F8C.10 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | dmd-3 | ||||||||
| DB_info | Database | AceView | gene | 5U124 | |||||
| WormQTL | gene | WBGene00012832 | |||||||
| WormFlux | gene | WBGene00012832 | |||||||
| NDB | locus_tag | CELE_Y43F8C.10 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00012832|UniProtKB=Q9XWN9 | |||||||
| family | PTHR12322 | ||||||||
| NCBI | gene | 189878 | |||||||
| RefSeq | protein | NM_001269953.2 | |||||||
| NM_001269954.4 | |||||||||
| SwissProt | UniProtAcc | Q9XWN9 | |||||||
| UniProt_GCRP | UniProtAcc | Q9XWN9 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:54 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 18 Jul 2005 13:34:00 | WBPerson2970 | Name_change | CGC_name | dmd-3 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | dmd | ||||||||
| Allele (137) | |||||||||
| Strain | WBStrain00031959 | ||||||||
| WBStrain00029935 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (30) | |||||||||
| Ortholog (33) | |||||||||
| Paralog | WBGene00003100 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00003114 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00007058 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00007929 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00022060 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00019521 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00020708 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00017326 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00007776 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | dmd-3 encodes a transcription factor with two DNA-binding Zn finger DM domains that is homologous to vertebrate dmrt-1 (OMIM:154230); dmd-3 is necessary for male-specific morphogenesis of the tail tip; dmd-3 acts with mab-3 to coordinate both tail tip cell fusion and retraction; dmd-3::YFP was expressed in a number of sexually dimorphic or sex-specific cells, including the tail tip, hindgut, B lineage, ray RnA neurons and somatic gonad; dmd-3 expression parallels tail tip remodeling, consistent with a cell autonomous, instructive role for dmd-3 in the control of morphogenesis; dmd-3 is a direct target of repression by TRA-1A in hermaphrodite tail tip and hindgut; sexually dimorphic dmd-3 expression determines the sexual specificity of tail tip morphogenesis; tail tip dmd-3 expression is regulated in an initial Wnt-independent induction of dmd-3, followed by Wnt-dependent maintenance and amplification; maintenance phase expression of dmd-3 requires lin-44 and tlp-1. | Paper_evidence | WBPaper00031953 | |||||
| WBPaper00038232 | |||||||||
| Curator_confirmed | WBPerson12884 | ||||||||
| Date_last_updated | 02 Jun 2011 00:00:00 | ||||||||
| Automated_description | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including nematode male tail tip morphogenesis; neuron differentiation; and regulation of reproductive process. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in neuronal cell body. Expressed in several structures, including PHC; epithelial cell; gonad; ray neuron type A; and tail hypodermis. Is an ortholog of human DMRTB1 (DMRT like family B with proline rich C-terminal 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | Y43F8C.10a | |||||||
| Y43F8C.10b | |||||||||
| Corresponding_CDS_history | Y43F8C.10:wp154 | ||||||||
| Corresponding_transcript | Y43F8C.10a.1 | ||||||||
| Y43F8C.10b.1 | |||||||||
| Other_sequence (32) | |||||||||
| Associated_feature | WBsf653584 | ||||||||
| WBsf978455 | |||||||||
| WBsf1003327 | |||||||||
| WBsf1003328 | |||||||||
| WBsf1003329 | |||||||||
| WBsf1003330 | |||||||||
| WBsf1021795 | |||||||||
| WBsf1021796 | |||||||||
| WBsf1021797 | |||||||||
| WBsf1021798 | |||||||||
| Transcription_factor | WBTranscriptionFactor000791 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00092994 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00019982 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00056519 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00077518 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr8158 | ||||||||
| Expr14446 | |||||||||
| Expr14652 | |||||||||
| Expr1025148 | |||||||||
| Expr1159992 | |||||||||
| Expr2010954 | |||||||||
| Expr2029193 | |||||||||
| Drives_construct | WBCnstr00000509 | ||||||||
| WBCnstr00000513 | |||||||||
| WBCnstr00013145 | |||||||||
| Construct_product | WBCnstr00000512 | ||||||||
| WBCnstr00000513 | |||||||||
| WBCnstr00000515 | |||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (69) | |||||||||
| Interaction (98) | |||||||||
| Map_info | Map | V | Position | 22.6873 | Error | 0.033316 | |||
| Positive | Positive_clone | Y43F8C | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 5352 | |||||||
| Pseudo_map_position | |||||||||
| Reference (33) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
