WormBase Tree Display for Gene: WBGene00016643

WBGene00016643 SMap: S_parent: Sequence: C44C1
  Identity: Version: 2
    Name: CGC_name: vps-45 Person_evidence: WBPerson426
      Sequence_name: C44C1.4
      Molecular_name: C44C1.4
        C44C1.4.1
        CE04214
      Other_name: CELE_C44C1.4 Accession_evidence: NDB BX284606
      Public_name: vps-45
    DB_info: Database: AceView gene XB590
        WormQTL gene WBGene00016643
        WormFlux gene WBGene00016643
        NDB locus_tag CELE_C44C1.4
        Panther gene CAEEL|WormBase=WBGene00016643|UniProtKB=H2KYN0
          family PTHR11679
        NCBI gene 180449
        RefSeq protein NM_171622.6
        TrEMBL UniProtAcc H2KYN0
        UniProt_GCRP UniProtAcc H2KYN0
        OMIM gene 610035
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:57 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 17 Mar 2006 15:11:54 WBPerson2970 Name_change: CGC_name: vps-45
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: vps
    Allele (53)
    Strain: WBStrain00001664
      WBStrain00007582
    RNASeq_FPKM (74)
    GO_annotation (12)
    Ortholog (36)
    Paralog: WBGene00006757 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00009654 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00015130 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00020298 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00016960 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Automated_description: Involved in pinocytosis and receptor-mediated endocytosis. Predicted to be located in Golgi membrane. Expressed in several structures, including coelomocyte; head; hypodermis; intestine; and muscle cell. Human ortholog(s) of this gene implicated in severe congenital neutropenia 5. Is an ortholog of human VPS45 (vacuolar protein sorting 45 homolog). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Experimental_model: DOID:0112132 Homo sapiens Paper_evidence: WBPaper00066193
          Curator_confirmed: WBPerson324
          Date_last_updated: 20 Nov 2023 00:00:00
    Potential_model: DOID:0112132 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:14579)
  Models_disease_asserted: WBDOannot00001370
  Molecular_info: Corresponding_CDS: C44C1.4
    Corresponding_CDS_history: C44C1.4b:wp271
    Corresponding_transcript: C44C1.4.1
    Other_sequence (62)
    Associated_feature: WBsf653678
      WBsf1003908
      WBsf1022193
      WBsf236984
  Experimental_info: RNAi_result (12)
    Expr_pattern: Chronogram1749
      Expr177
      Expr4768
      Expr5498
      Expr1019066
      Expr1037156
      Expr1146433
      Expr2018031
      Expr2036168
    Drives_construct: WBCnstr00002503
      WBCnstr00012230
      WBCnstr00027918
    Construct_product: WBCnstr00004752
      WBCnstr00012230
      WBCnstr00020072
      WBCnstr00022652
      WBCnstr00027918
    Microarray_results (27)
    Expression_cluster (80)
    Interaction (346)
  Map_info: Map: X Position: -18.8773 Error: 0.001578
    Positive: Positive_clone: C44C1 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (13)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene