WormBase Tree Display for Gene: WBGene00016670

WBGene00016670 SMap: S_parent: Sequence: C45G7
  Identity: Version: 2
    Name: CGC_name: ilys-3 Person_evidence: WBPerson2531
      Sequence_name: C45G7.3
      Molecular_name: C45G7.3
        C45G7.3.1
        CE24850
      Other_name: CELE_C45G7.3 Accession_evidence: NDB BX284604
      Public_name: ilys-3
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:57 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 18 May 2007 16:58:23 WBPerson2970 Name_change: CGC_name: ilys-3
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: ilys
    Allele (30)
    Strain: WBStrain00037363
      WBStrain00004732
      WBStrain00004740
      WBStrain00004741
    RNASeq_FPKM (74)
    GO_annotation (26)
    Ortholog (26)
    Paralog: WBGene00016668 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00016669 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00017691 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00016958 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00020982 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
    Structured_description: Automated_description: Enables lysozyme activity. Involved in antibacterial innate immune response and defense response to Gram-positive bacterium. Located in late endosome lumen; lysosomal lumen; and recycling endosome lumen. Expressed in coelomocyte; hypodermis; intestinal cell; and terminal bulb. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C45G7.3
    Corresponding_transcript: C45G7.3.1
    Other_sequence (13)
    Associated_feature: WBsf228023
  Experimental_info: RNAi_result: WBRNAi00092215 Inferred_automatically: RNAi_primary
      WBRNAi00011984 Inferred_automatically: RNAi_primary
      WBRNAi00070080 Inferred_automatically: RNAi_primary
      WBRNAi00000480 Inferred_automatically: RNAi_primary
      WBRNAi00029837 Inferred_automatically: RNAi_primary
      WBRNAi00042538 Inferred_automatically: RNAi_primary
      WBRNAi00092218 Inferred_automatically: RNAi_primary
      WBRNAi00078253 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr9963
      Expr13079
      Expr13080
      Expr1014535
      Expr1146525
      Expr2030958
    Drives_construct: WBCnstr00014976
      WBCnstr00015097
      WBCnstr00027901
      WBCnstr00038029
      WBCnstr00038573
    Construct_product: WBCnstr00027901
    Microarray_results (16)
    Expression_cluster: WBPaper00027339:daf-12(rh273)_upregulated
      WBPaper00028802:intestine_unique
      WBPaper00031486:daf-16_downregulated
      WBPaper00032031:DConiospora_downregulated_cDNA_12h
      WBPaper00032031:DConiospora_downregulated_OligoArray_24h
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00033070:Elbe_upregulated
      WBPaper00033444:BacteriaDiet_regulated
      WBPaper00034636:heat_shock_upregulated
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_larva_enriched
      WBPaper00037950:dopaminergic-neurons_larva_SelectivelyEnriched
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00038168:lin-15B(n744)_downregulated
      WBPaper00038438:D.coniospora_12hr_upregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
      WBPaper00038438:Harposporium_24hr_downregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_downregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_downregulated_TilingArray
      WBPaper00038438:S.marcescens_24hr_downregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_downregulated_TilingArray
      WBPaper00040209:B.thuringiensis_downregulated_MY15
      WBPaper00040209:B.thuringiensis_downregulated_MY18
      WBPaper00042561:smgl-1(RNAi)_downregulated
      WBPaper00042561:smgl-2(RNAi)_upregulated
      WBPaper00044030:nhr-8(hd117)_downregulated
      WBPaper00044316:CH3HgCl_7.5uM_downregulated
      WBPaper00044578:reduced-humidity_downregulated_microarray
      WBPaper00045017:blmp-1(tm548)_upregulated
      WBPaper00045314:S.aureus-induced_N2
      WBPaper00045390:tunicamycin_downregulated
      WBPaper00045401:N.parisii_64h_downregulated
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045774:clk-1_downregulated
      WBPaper00045918:96h_infection_recovery_downregulated
      WBPaper00045918:120h_infection_recovery_downregulated
      WBPaper00045971:tunicamycin_upregulated_control
      WBPaper00046527:glucose_upregulated
      WBPaper00046741:Garlic-Extract_upregulated_mRNA
      WBPaper00048980:aging_upregulated
      WBPaper00049217:TCER-1_downregulated
      WBPaper00049334:CE_intestine_enriched
      WBPaper00049484:elt-2(RNAi)_downregulated_L1
      WBPaper00049498:npr-1(ur89)_regulated_4
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049920:Glucose-Diet_upregulated_N2
      WBPaper00050080:rbr-2(tm3141)_upregulated
      WBPaper00050344:ASER-neuron_enriched
      WBPaper00050370:dpy-21(e428)_L3_upregulated
      WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
      WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_adult_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_adult_25C
      WBPaper00050504:hrp-2(RNAi)_upregulated
      WBPaper00050712:RC301_vs_DA650_4h-PA_upregulated
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00051164:Nel-protein-infection_regulated
      WBPaper00051265:F1_hrde-1(tm1200)_upregulated
      WBPaper00051265:F1_morc-1(tm6048)_upregulated
      WBPaper00051352:Long-Term-Association-Memory_upregulated
      WBPaper00051388:Glucose-diet_upregulated
      WBPaper00051540:exc-7(csb29)_upregulated
      WBPaper00051555:atm-1(gk186)_regulated_protein
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053154:human-amyloid-beta_tau_regulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053295:lin-22(ot269)_upregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
      WBPaper00053318:mir-71(n4115)_upregulated_mRNA
      WBPaper00053388:dauer_regulated_Cluster2
      WBPaper00053402:cco-1(RNAi)_upregulated
      WBPaper00053771:up_at_24h-NaCl
      WBPaper00053771:up_at_dpy-7(e88)
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00053814:15C_downregulated_PY79
      WBPaper00053814:OP50_vs_PY79_downregulated_PY79
      WBPaper00054493:hpl-2(tm1489)_upregulated
      WBPaper00054796:cav-1(RNAi)_downregulated
      WBPaper00054810:deoxynivalenol_downregulated
      WBPaper00055013:hmg-4(RNAi)_upregulated
      WBPaper00055013:spt-16(RNAi)_upregulated
      WBPaper00055137:S.maltophilia_downregulated
      WBPaper00055354:eat-2(ad1116)_upregulated
      WBPaper00055354:Rapamycin-Psora_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055354:Rifampicin-Psora_upregulated
      WBPaper00055386:daf-2(e1370)_upregulated
      WBPaper00055827:pfd-6(gk493446)_downregulated
      WBPaper00055941:nuo-6(qm200);atfs-1(gk3094)_upregulated
      WBPaper00055941:nuo-6(qm200)_upregulated
      WBPaper00055969:electromagnetic-field_upregulated
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_upregulated_N2
      WBPaper00056139:soil-microbiota_upregulated
      WBPaper00056165:mina-1(ok1521)_downregulated_transcript
      WBPaper00056218:daf-16(mu86)_upregulated_Day7
      WBPaper00056284:ints-5(RNAi)_upregulated
      WBPaper00056290:hsp-6(mg585)_downregulated
      WBPaper00056443:DietaryRestriction_upregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056731:human-amylin_upregulated
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057006:DietaryRestriction_upregulated
      WBPaper00057041:spc-1(cas971)_upregulated
      WBPaper00057068:ints-4(RNAi)_upregulated_Cadmium
      WBPaper00058711:paraquat_downregulated
      WBPaper00058948:PA14_upregulated
      WBPaper00059117:B.subtilis_upregulated
      WBPaper00059253:sucrose_stearic-acid_upregulated
      WBPaper00059253:sucrose_upregulated
      WBPaper00059426:SiO2-nanoparticles_upregulated
      WBPaper00059609:malt-1_ilc-17.1_nfki-1_upregulated
      WBPaper00059754:C.neoformans_H99_upregulated
      WBPaper00059754:E.faecalis_OG1RF_upregulated
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00059839:S.maltophilia_regulated
      WBPaper00059895:wounding_upregulated
      WBPaper00059987:Wounding_upregulated
      WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060399:pqm-1(ok485)_downregulated_CoCl2_6hr
      WBPaper00060434:pH4.33_vs_pH6.33_uprgulated
      WBPaper00060703:nas-38(ok3407)_upregulated
      WBPaper00060764:swsn-9(ok1354)_upregulated
      WBPaper00060871:M.humicola-extract_4h_regulated
      WBPaper00060911:prx-5(RNAi)_upregulated_mRNA
      WBPaper00060921:cat-2(e1112)_upregulated
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061007:X.citri_upregulated
      WBPaper00061081:E.faecalis_upregulated_N2
      WBPaper00061081:E.faecalis_upregulated_skpo-1(ok1640)
      WBPaper00061274:hypergravity_10xg_downregulated
      WBPaper00061274:hypergravity_15xg_downregulated
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061424:Diet_MYb120_upregulated
      WBPaper00061424:Diet_MYb131_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
      WBPaper00061527:W01F3.2_1554-Y106G6D.8
      WBPaper00061572:oleic-acid-specific_mating_upregulated
      WBPaper00061590:CGP37157_downregulated
      WBPaper00061613:human-alpha-Synuclein(A53T)_upregulated
      WBPaper00061613:human-amyloid-beta_alpha-Synuclein(A53T)_upregulated
      WBPaper00061653:alh-4(hj221)_upregulated
      WBPaper00061753:csr-1(tor159)_upregulated_25C
      WBPaper00061952:daf-18(nr2037)_downregulated
      WBPaper00061952:daf-18(yh1)_downregulated
      WBPaper00062156:jmjd-5(zr1234)_upregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062347:blmp-1(tm548)_upregulated
      WBPaper00062354:H.zoospora_6h_regulated
      WBPaper00062440:crh-1(syb385)_downregulated
      WBPaper00062456:doxycycline_upregulated_N2_transcript
      WBPaper00062497:xpf-1(tm2842)_downregulated
      WBPaper00062585:hlh-26(ok1453)_downregulated_E.faecium
      WBPaper00062590:Aging_upregulated_neuron
      WBPaper00062672:let-418(n3536)dcp-66(RNAi)_upregulated
      WBPaper00062684:pathogen_upregulated_N2
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064130:Beta-Amyloid_24h_upregulated_mRNA
      WBPaper00064156:lbp-3(overexpress)_upregulated
      WBPaper00064156:lipl-4(overexpress)_upregulated
      WBPaper00064306:Agaro-oligosaccharides_upregulated
      WBPaper00064632:daf-2(e1370)_upregulated_intestine
      WBPaper00064661:lpd-3(ok2138)_upregulated
      WBPaper00064762:freezing-thaw_regulated
      WBPaper00064788:ketamine_upregulated
      WBPaper00064939:vit-5(RNAi)_upregulated
      WBPaper00065029:cadmium_upregulated
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065096:npr-8(ok1439)_downregulated_Day1_25C
      WBPaper00065392:Lb.rhamnosus_downregulated
      WBPaper00065392:P.pentosaceus_downregulated
      WBPaper00065581:hpk-1(pk1393)_upregulated
      WBPaper00065734:unc-25(e156)_upregulated
      WBPaper00065746:eat-2(ad1113)_downregulated
      WBPaper00065945:epidermis-rpoa-2(-)_upregulated_protein
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065995:M.humicola-extract_downregulated_N2
      WBPaper00065995:M.humicola-extract_downregulated_old-1(ok1273)
      WBPaper00066110:tetraploid_vs_diploid_upregulated
      WBPaper00066118:cyclobutrifluram_upregulated
      WBPaper00066232:ash-2(RNAi)_downregulated_WT
      WBPaper00066232:hsf-1(RNAi)_downregulated_WT
      cgc4489_group_12
      WBPaper00005124:progesterone_10-5M_regulated
      WBPaper00005124:progesterone_10-9M_regulated
      WBPaper00006465:IV_ethanol_late_repression
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026952:class_B
      WBPaper00027111:eri-1(mg366)_upregulated
      WBPaper00027342:alpha-Synuclein(A53T)_downregulated
      WBPaper00028482:PA14_downregulated
      WBPaper00029437:dcr-1_upregulated
      WBPaper00030985:Photorhabdus_luminescens_upregulated
      WBPaper00031832:slr-2_regulated
      WBPaper00032062:age_regulated_genes
      WBPaper00034661:AgNPs_downregulated
      WBPaper00034757:up_by_oxidative_stress
      WBPaper00035873:dpy-10_regulated
      WBPaper00035873:osm-7_regulated
      WBPaper00035873:osm-8_regulated
      WBPaper00035873:osm-11_regulated
      WBPaper00036286:Pattern_B
      WBPaper00036286:Pattern_F
      WBPaper00036464:S.aureus-RN6390_regulated
      WBPaper00039851:HK_C_albicans_vs_HK_OP50
      WBPaper00039851:Live_C_albicans_vs_HK_OP50
      WBPaper00040184:hcf-1down_sir-2.1down_daf-2down
      WBPaper00040808:1.1uM_ivermectin_upregulated
      WBPaper00040821:Au-NP_regulated
      WBPaper00040858:eQTL_age_regulated_aging
      WBPaper00040858:eQTL_regulated_aging
      WBPaper00040858:eQTL_regulated_old
      WBPaper00040858:eQTL_regulated_reproductive
      WBPaper00040963:Q50_up
      WBPaper00040963:Q100_down
      WBPaper00040998:nhr-80_regulated
      WBPaper00041002:HF_3d_0.2mM_Up
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041002:HF_11d_0.2mM_Down
      WBPaper00041002:HF_11d_2.0mM_Up
      WBPaper00041002:HQ_3d_2.0mM_Up
      WBPaper00041174:environmental
      WBPaper00041174:environmental_prime
      WBPaper00041211:RPW-24_Down
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041609:hpl-1_hpl-2_downregulated
      WBPaper00041906:I-4317_vs_OP50_10d
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_24h
      WBPaper00041960:daf-16_fasting_upregulated
      WBPaper00041960:jun-1_fasting_upregulated
      WBPaper00041960:kgb-1_fasting_upregulated
      WBPaper00041960:N2_fasting_upregulated
      WBPaper00041960:N2_fasting_upregulated_9hto12h
      WBPaper00041960:N2_fasting_upregulated_anytime
      WBPaper00042128:gei-8(ok1671)_downregulated
      WBPaper00042331:a-SWCNTs_downregulated
      WBPaper00044091:Bpseudomallei_repressed_4h
      WBPaper00044091:Bpseudomallei_repressed_8h
      WBPaper00045015:nhr-25(RNAi)_upregulated
      WBPaper00045673:colistin_upregulated
      WBPaper00046083:pmk-1(km25)_OP50_upregulated
      WBPaper00046548:dafachronic-acid_upregulated
      WBPaper00046853:AOBr_M.aeruginosa-batch-culture_downregulated
      WBPaper00047021:MWCNT_downregulated
      WBPaper00047070:N2_starvation_upregulated
      WBPaper00047070:xpa-1_UV_upregulated
      WBPaper00048624:hlh-25(ok1710)_downregulated
      WBPaper00048637:lin-35(n745)_starvation_upregulated
      WBPaper00049311:Ag-MNP_regulated
      WBPaper00049311:AgNO3_regulated
      WBPaper00050538:Fasting_upregulated
      WBPaper00050538:Fasting_upregulated_cholesterol-dependent
      WBPaper00050767:Octopamine_induced
      WBPaper00053550:daf-19(m86)_upregulated_L1
      WBPaper00053688:E.faecalis_upregulated
      WBPaper00055899:2,4-Dinitroanisole_regulated
      WBPaper00055899:nitroguanidine_regulated
      [cgc5376]:let-60(G12V)-regulated_genes
      [cgc5976]:class_1
    Interaction (23)
    WBProcess: WBbiopr:00000008
  Map_info: Map: IV Position: -7.42586 Error: 0.019843
    Positive: Positive_clone: C45G7 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (15)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene