WormBase Tree Display for Variation: WBVar00000004
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| WBVar00000004 | Name | Public_name | ad418 | |||||
|---|---|---|---|---|---|---|---|---|
| Sequence_details | SeqStatus | Pending_curation | ||||||
| Variation_type | Allele | |||||||
| Origin | Species | Caenorhabditis elegans | ||||||
| Laboratory | DA | |||||||
| Status | Live | |||||||
| Affects | Gene | WBGene00000086 | ||||||
| Interactor | WBInteraction000052182 | |||||||
| Genetics | Mapping_data | In_2_point | 4467 | |||||
| 4570 | ||||||||
| In_multi_point | 1548 | |||||||
| 1549 | ||||||||
| 1586 | ||||||||
| Description | Phenotype | WBPhenotype:0000061 | Paper_evidence | WBPaper00024698 | ||||
| Curator_confirmed | WBPerson712 | |||||||
| Remark | Mean life-span extended by 16%. | Paper_evidence | WBPaper00024698 | |||||
| Curator_confirmed | WBPerson712 | |||||||
| WBPhenotype:0000204 | Paper_evidence | WBPaper00001709 | ||||||
| Curator_confirmed | WBPerson2021 | |||||||
| Remark | Defect in the anterior body wall muscle contraction step of the defecation cycle | Paper_evidence | WBPaper00001709 | |||||
| Curator_confirmed | WBPerson2021 | |||||||
| WBPhenotype:0000650 | Person_evidence | WBPerson261 | ||||||
| Curator_confirmed | WBPerson712 | |||||||
| Remark | defecation defective | Person_evidence | WBPerson261 | |||||
| Curator_confirmed | WBPerson712 | |||||||
| WBPhenotype:0000651 | Person_evidence | WBPerson261 | ||||||
| Curator_confirmed | WBPerson712 | |||||||
| Remark | slightly constipated | Person_evidence | WBPerson261 | |||||
| Curator_confirmed | WBPerson712 | |||||||
| WBPhenotype:0000996 | Paper_evidence | WBPaper00001709 | ||||||
| Curator_confirmed | WBPerson2021 | |||||||
| Remark | Defect in the expulsion step of the defecation cycle | Paper_evidence | WBPaper00001709 | |||||
| Curator_confirmed | WBPerson2021 | |||||||
| WBPhenotype:0001793 | Person_evidence | WBPerson261 | ||||||
| Curator_confirmed | WBPerson712 | |||||||
| Remark | anterior body contraction (aBoc) and expulsion muscle contraction (Exp) missing in five of six defecation cycles, adult males unaffected and mate well. | Person_evidence | WBPerson261 | |||||
| Curator_confirmed | WBPerson712 | |||||||
| Phenotype_not_observed | WBPhenotype:0001616 | Paper_evidence | WBPaper00024698 | |||||
| Curator_confirmed | WBPerson712 | |||||||
| Remark | Trimethadione significantly extended life-span of mutant animals (N=113)(2 ind.exp.), as observed for WT animals. | Paper_evidence | WBPaper00024698 | |||||
| Curator_confirmed | WBPerson712 | |||||||
| Phenotype_assay | Treatment | Lifespan analysis was performed on animals exposed to 4 mg/ml of the drug from fertilization until death. Animals were cultured on NGM plates containing the drug and seeded with OP50. | Paper_evidence | WBPaper00024698 | ||||
| Curator_confirmed | WBPerson712 | |||||||
| Temperature | 20°C | Paper_evidence | WBPaper00024698 | |||||
| Curator_confirmed | WBPerson712 | |||||||
| WBPhenotype:0001617 | Paper_evidence | WBPaper00024698 | ||||||
| Curator_confirmed | WBPerson712 | |||||||
| Remark | Ethosuximide significantly extended life-span of mutant animals (N=236)(4 ind.exp.), as observed for WT animals. | Paper_evidence | WBPaper00024698 | |||||
| Curator_confirmed | WBPerson712 | |||||||
| Phenotype_assay | Treatment | Lifespan analysis was performed on animals exposed to 4 mg/ml of the drug from fertilization until death. Animals were cultured on NGM plates containing the drug and seeded with OP50. | Paper_evidence | WBPaper00024698 | ||||
| Curator_confirmed | WBPerson712 | |||||||
| Temperature | 20°C | Paper_evidence | WBPaper00024698 | |||||
| Curator_confirmed | WBPerson712 | |||||||
| Reference | WBPaper00015225 | |||||||
| WBPaper00001709 | ||||||||
| WBPaper00014052 | ||||||||
| WBPaper00017299 | ||||||||
| WBPaper00024698 | ||||||||
| WBPaper00013858 | ||||||||
| Method | Allele |
