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WormBase Tree Display for Variation: WBVar00088418

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Name Class

WBVar00088418NamePublic_nameky200
Other_nameky200ts
Sequence_detailsSeqStatusPending_curation
Variation_typeAllele
OriginSpeciesCaenorhabditis elegans
StrainWBStrain00005236
LaboratoryCX
StatusLive
AffectsGeneWBGene00004729
DescriptionPhenotypeWBPhenotype:0000002Paper_evidenceWBPaper00003665
Curator_confirmedWBPerson712
RemarkmildPaper_evidenceWBPaper00003665
Curator_confirmedWBPerson712
WBPhenotype:0000062Paper_evidenceWBPaper00003665
Curator_confirmedWBPerson712
Remarkanimals showed decreased viability at 25 deg C.Paper_evidenceWBPaper00003665
Curator_confirmedWBPerson712
Temperature_sensitiveHeat_sensitive25Paper_evidenceWBPaper00003665
Curator_confirmedWBPerson712
WBPhenotype:0000565Paper_evidenceWBPaper00003665
Curator_confirmedWBPerson712
RemarkmildPaper_evidenceWBPaper00003665
Curator_confirmedWBPerson712
Temperature_sensitiveHeat_sensitive25Paper_evidenceWBPaper00003665
Curator_confirmedWBPerson712
WBPhenotype:0000883Paper_evidenceWBPaper00035405
Curator_confirmedWBPerson2021
Remarksax-3 mutants had anteriorly displaced nerve ringsPaper_evidenceWBPaper00035405
Curator_confirmedWBPerson2021
Temperature_sensitiveHeat_sensitivePaper_evidenceWBPaper00035405
Curator_confirmedWBPerson2021
WBPhenotype:0001224Paper_evidenceWBPaper00003665
Curator_confirmedWBPerson712
RemarkOnly 20% of mutants showed wild-type ASI amphid neurons outgrowth at 25 deg C. At 20 deg C. over 95% animals were like wild-type. At 25 deg C. axons prematurely terminated (14%), grew laterally before turning dorsally (23%), or grew anteriorly (59%).Paper_evidenceWBPaper00003665
Curator_confirmedWBPerson712
PenetranceIncomplete74%Paper_evidenceWBPaper00003665
Curator_confirmedWBPerson712
EQ_annotationsAnatomy_termWBbt:0005666PATO:0000460Paper_evidenceWBPaper00003665
Curator_confirmedWBPerson712
Temperature_sensitiveHeat_sensitive25Paper_evidenceWBPaper00003665
Curator_confirmedWBPerson712
Phenotype_assayGenotypekyIs128[str-3::GFP]Paper_evidenceWBPaper00003665
Curator_confirmedWBPerson712
ReferenceWBPaper00018582
WBPaper00035405
WBPaper00003665
MethodAllele